Advantage Chewable 112 mg Chewable Tablets for Dogs (>2.5–5.5 kg)

Parasites need to start feeding on the host to become exposed to lotilaner;
therefore, the risk of the transmission of parasite borne diseases cannot be
completely excluded.
The possibility that other animals in the same household can be a source of re-
infection with fleas should be considered, and these should be treated as
necessary with an appropriate product.
All stages of fleas can infest the dog’s bedding and regular resting areas such
as carpets and soft furnishings. In case of massive flea infestation and at the
beginning of the control measures, these areas should be treated with a
suitable environmental product and then vacuumed regularly.

i). Special precautions for use in animals
All safety and efficacy data have been acquired from dogs and puppies 8
weeks of age and older and 1.3 kg of body weight and greater. In the absence
of available data, a veterinarian should be consulted before treatment in
puppies younger than 8 weeks of age or less than 1.3 kg of body weight.
Inform your veterinary surgeon that you are using this product if s/he provides
your dog with any other medication.
ii). Special precautions to be taken by the person administering the veterinary
medicinal product to animals
Wash hands after handling the product.
Special precautions for the protection of the environment:
The active substance is mostly excreted in the faeces (poo) and may be toxic to
non-target organisms. In order to avoid contamination of the environment,
ensure that dog faeces are bagged up and disposed of safely.
iii) Other precautions
Not applicable

Revised: December 2025
AN: 02790/2025