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AVM-GSL Over the Counter Companion Animal

Fleasolve 50 mg Spot-on Solution for Cats

Active ingredient: Fipronil

Form

Spot-on

Species

Cats

Manufacturer

Naqua Ltd

VMD MA No.

49507/5000

What it's used for

Treatment of flea (Ctenocephalides spp.) and tick (Dermacentor reticulatus) infestations. The product has a persistent insecticidal efficacy for up to 5 we...

Full indications, dosage and side effects ↓
View official SPC (PDF)

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Paying less for Fipronil

  1. 1

    Ask your vet for a written prescription

    They must provide one on request. Under the CMA Order the fee is capped at £21 from 2027.

  2. 2

    Fill it at a registered online retailer

    The CMA found online pharmacies 50–60% cheaper than practice dispensing on common medicines — typically £200–£300 a year.

Clinical information

Fleasolve 50 mg Spot-on Solution for Cats — SPC Details

Source: VMD Summary of Product Characteristics (SPC). Last updated 26 Mar 2026.

Treatment

of

flea

(Ctenocephalides

spp.)

and

tick

(Dermacentor

reticulatus) infestations.
The product has a persistent insecticidal efficacy for up to 5 weeks against fleas
(Ctenocephalides felis).
The product has a persistent acaricidal efficacy for up to 2 weeks against ticks
(Rhipicephalus sanguineus, Ixodes ricinus, Dermacentor reticulatus). If ticks of
some species (Rhipicephalus sanguineus ) are present when
the product is applied, all the ticks may not be killed within the first 48 hours but
they may be killed within a week.

Revised: October 2025
MA split from NI Expiry following AN: 02210/2025Page 2 of 8
Route of administration and dosage:
External use only.
Administer by topical application to the skin 1 pipette of 0.5 ml per animal.
Method of administration:
Thermoformed pipettes:
Hold the pipette upright. Tap the narrow part of the pipette to ensure that the
contents are within the main body of the pipette. Break the snap-off top of the
spot-on pipette along the scored line.
Part the pet’s coat until its skin is visible. Place the tip of the pipette directly
against the bared skin and squeeze gently several times to empty its contents
Repeat this procedure at one or two different points along the cat’s back,
preferably at the base of the head and between the shoulders.
(Note: the shape of the marketed pipettes can be different as well as the
pictures on the marketed boxes/package leaflets.)
Polypropylene pipettes:
Remove the pipette from the blister packaging. Hold the pipette in an upright

Revised: October 2025
MA split from NI Expiry following AN: 02210/2025Page 5 of 8
position, twist and pull the cap off. Turn the cap around and place the other end
of the cap back on the pipette. Twist the cap to break the seal, then remove the
cap from the pipette.
Part the pet’s coat until its skin is visible. Place the tip of the pipette directly
against the bared skin and squeeze gently several times to empty its contents.
Repeat this procedure at one or two points along the cat’s back, preferably at
the base of the head and between the shoulders.
It is important to make sure that the product is applied to an area where the
animal cannot lick it off, and to make sure that animals do not lick each other
following treatment.
Care should be taken to avoid excessive wetting of the hair with the product
since this will cause a sticky appearance of hairs at the treatment spot.
However, should this occur, it will disappear within 24 hours post application.
White deposits may also be seen at the site for up to 48 hours after
application. Treatment schedule:
For optimal control of flea and/or tick infestation the treatment schedule can be
based on the local epidemiological situation.
In the absence of safety studies, the minimum treatment interval is 4 weeks.
In the absence of available data, the product should not be used on kittens less
than 2 months old and/or weighing less than 1 kg.
Do not use on sick (systemic diseases, fever…) or convalescent
animals. Do not use in rabbits, due to a risk of adverse drug reactions
or even death.
Do not use in known cases of hypersensitivity to the active substance or to any
of excipients.
If licking occurs, a brief period of hypersalivation may be observed due mainly to
the nature of the carrier.
A Very rarely transient cutaneous reactions at the application site (squamosis,
local alopecia, pruritus, erythema) and general pruritus or alopecia have been
reported after use. Hypersalivation, reversible neurologic symptoms
(hyperesthesia, depression, nervous symptoms) or vomiting have also been
observed very rarely after use.
The frequency of adverse reactions is defined using the following convention:
- very common (more than 1 in 10 animals treated displaying
adverse

reaction(s))
- common (more than 1 but less than 10 animals in 100 animals treated)
- uncommon (more than 1 but less than 10 animals in 1,000 animals treated)
- rare (more than 1 but less than 10 animals in 10,000 animals treated)
- very rare (less than 1 animal in 10,000 animals treated, including
isolated reports).
Fleas from pets often infest the animal's basket, bedding and regular resting
areas such as carpets and soft furnishings which should be treated, in case of
massive infestation and at the beginning of the control measures, with a suitable
insecticide and vacuumed regularly.
The product does not prevent ticks from attaching to the animals. If the animal
has been treated prior to exposure to the ticks, the ticks will be killed in the first
24-48 hours after attachment. This will usually be prior to engorgement,
minimising but not excluding the risk of transmission of diseases. Once dead,
ticks will often drop off the animal, but any remaining ticks may be removed with
a gentle pull.
No data on the effect of bathing/shampooing on the efficacy of the product in
cats are available. However, based on information available for dogs,
shampooing an hour prior to treatment does not affect the efficacy of the
product against fleas.
For optimum control of flea problems in a multi-pet household, all dogs and cats
in the household should be treated with a suitable insecticide.

in animals
Avoid contact with the animal’s eyes. In the case of accidental eye contact,
immediately rinse the eyes with clean water.
Do not apply the product on wounds or damaged skin.
Special precautions to be taken by the person administering the
veterinary medicinal product to animals
Keep pipettes in original packaging until ready to use.
People with a known hypersensitivity to fipronil or excipients (see section 6.1.)

Revised: October 2025
MA split from NI Expiry following AN: 02210/2025Page 3 of 8
should avoid contact with the veterinary medicinal product.
This product can cause mucous membrane and eye irritation. Therefore,
contact between the product and the mouth or eyes should be avoided.
In the case of accidental eye contact, immediately rinse the eyes with clean
water. If eye irritation persists seek medical advice and show the package
leaflet or the label to the physician.
Avoid contents coming into contact with the skin. If this occurs, wash hands with
soap and water.
Ingestion of the product is harmful. Prevent children getting access to the
pipettes and discard the used pipettes immediately after applying the product.
In case of accidental ingestion of product seek medical advice immediately.
Treated animals should not be handled until the application site is dry, and
children should not be allowed to play with treated animals until the application
site is dry. It is therefore recommended that animals are not treated during the
day, but should be treated during the early evening, and that recently treated
animals should not be allowed to sleep with owners, especially children.
Do not smoke, drink or eat during application. Wash hands after use.
Other precautions
The alcohol carrier may have adverse effects on painted, varnished or
other household surfaces or furnishings.
None known.
Store below C. Store in a dry place. Store in the original package.
Not applicable.
5.

This information is sourced from the official Summary of Product Characteristics (SPC) published by the Veterinary Medicines Directorate (VMD). It is provided for informational purposes only and does not replace professional veterinary advice. Always consult your vet before administering any medication.

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