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NFA-VPS Over the Counter Companion Animal

Fiproclear 268 mg Spot-on Solution for Large Dogs

Active ingredient: Fipronil

Form

Spot-on

Species

Dogs

Manufacturer

Norbrook Laboratories Limited

VMD MA No.

02000/4352

What it's used for

For the treatment of infestations by fleas (Ctenocephalides ). The product shows immediate insecticidal effect and persistent insecticidal activity against...

Full indications, dosage and side effects ↓
View official SPC (PDF)

The prescription itself has a price. See what practices near you charge for a consultation and the written prescription fee.

Paying less for Fipronil

  1. 1

    Ask your vet for a written prescription

    They must provide one on request. Under the CMA Order the fee is capped at £21 from 2027.

  2. 2

    Fill it at a registered online retailer

    The CMA found online pharmacies 50–60% cheaper than practice dispensing on common medicines — typically £200–£300 a year.

Clinical information

Fiproclear 268 mg Spot-on Solution for Large Dogs — SPC Details

Source: VMD Summary of Product Characteristics (SPC). Last updated 26 Mar 2026.

For the treatment of infestations by fleas (Ctenocephalides ). The product
shows immediate insecticidal effect and persistent insecticidal activity against
new infestations by adult fleas for up to 8 weeks.
The product has a persistent acaricidal efficacy against for up to
2 weeks,
reticulatus for up to 4 weeks. If ticks of these species are present when the
product is applied, all ticks will not be killed within the first 48 hours but they
may be killed within a week.
The product can be used as part of a treatment programme for Flea Allergy
Dermatitis where this has been previously diagnosed by a Veterinary Surgeon.
Route of administration: By topical application to the skin.
For external use only. Apply the product directly to the skin based on weight
of the animal.
Animals should be weighed accurately prior to treatment.
Dosage –
1 pipette of 2.68 ml per dog weighing over 20 kg and up to 40 kg bodyweight
corresponding to a minimum recommended dose of 6.7 mg/kg of fipronil.
.
Method of Administration: Hold upright. Tap the narrow part of the pipette to
ensure the contents are within the main body of the pipette. Break back the
snap-off top from the spot-on pipette along the scored line. Part the coat
between the shoulder blades until the skin is visible. Place the tip of the
pipette on the skin and squeeze gently at one or two spots to empty its
contents onto the skin.
It is important to make sure that the product is applied to an area where the
animal cannot lick it off, and to make sure that the animals do not lick each
other following treatment.

Revised: May 2018
AN: 01363/2017
Care should be taken to avoid excessive wetting of the hair with the product
since this will cause a sticky appearance of hairs at the treatment spot.
However, should this occur, it will disappear within 48 hours post application.
For the optimal control of infestation by flea and or/tick the treatment schedule
can be based on local epidemiological situation.
In the absence of safety studies, the minimum treatment interval is 4 weeks.
Do not use in dogs weighing less than 20 kg.

Revised: May 2018
AN: 01363/2017
In the absence of available data, the product should not be used in puppies
less than 8 weeks old.
Do not use in sick (systemic diseases, fever…) or convalescent animals.
Do not use in rabbits, as adverse reactions and even death could occur.
This product is specifically developed for dogs. Do not use in cats, as this
could lead to overdosing.
Do not use in cases of known hypersensitivity to fipronil or to any of the
excipients.
If licking occurs, a brief period of hypersalivation may be observed due mainly
to the nature of the carrier.
The following adverse reactions are reported very rarely:
•
local alopecia, pruritus, erythema)
•
•
•
•
•
•

Revised: May 2018
AN: 01363/2017
The frequency of adverse reactions is defined using the following convention:
-
reports)
The product does not prevent ticks from attaching to the animals, but ticks
may be killed in the first 24-48 hours after attachment prior to full engorgement
and therefore minimising but not excluding the risk of transmission of
diseases. Once dead, ticks will often drop off the animal, but any remaining
ticks may easily be removed by a gentle pull.
When used as part of a strategy for the treatment of Flea Allergy Dermatitis,
monthly applications to the allergic patient and to other dogs in the household
are recommended.
For optimal control of flea infestation in multi-pet household, all dogs and cats
in the house should be treated with a suitable insecticide.
Fleas from pets often infest the animal’s basket, bedding and regular resting
areas such as carpets and soft furnishings which should be treated, in case of
massive infestation and at the beginning of the control measures, with a
suitable insecticide and vacuumed regularly.
Avoid frequent swimming or shampooing of the animal because the
maintenance of effectiveness of the product in these cases has not been
tested.

(i) Special precautions for use in animals
Avoid contact with the animal’s eyes. In the case of accidental eye contact
immediately and thoroughly flush the eyes with water.
It is important to make sure that the product is applied to an area where the
animal cannot lick it off, and to make sure that animals do not lick each other
following treatment.
Do not apply the product on wounds or damaged skin.

Revised: May 2018
AN: 01363/2017
(ii) Special precautions to be taken by the person administering the
veterinary medicinal product to the animals
This product can cause mucous membrane and eye irritation. Therefore,
contact of the product with the mouth and eyes should be avoided.
In cases of accidental eye contact, immediately and thoroughly rinse the eye
with plain water. If eye irritation persists seek medical advice and show the
package leaflet or the label to a physician.
People with a known hypersensitivity to fipronil or excipients (section 6.1)
should avoid contact with the veterinary product.
Avoid contents coming into contact with the fingers. If this occurs, wash
hands with soap and water.
Wash hands after use. Do not smoke, drink or eat during application.
Treated animals should not be handled until this application site is dry, and
children should not be allowed to play with treated animals until the application
site is dry. It is therefore recommended that animals are not treated during the
day, but should be treated during the early evening, and that recently treated
animals should not be allowed to sleep with owners, especially children.
Keep pipettes in original packaging and dispose of used pipettes immediately.
This product is flammable. Keep away from heat, sparks, open flame or other
sources of ignition.
(iii) Other precautions
Fipronil may adversely affect aquatic organisms. Dogs should not be allowed
to swim in watercourses for 2 days after application.
The alcohol carrier may have adverse effect on painted, varnished or other
household surfaces or furnishings.
None known.
This medicinal product does not require any special temperature storage
conditions.
Store in the original container in order to protect from light and moisture.
Not applicable.
5.

This information is sourced from the official Summary of Product Characteristics (SPC) published by the Veterinary Medicines Directorate (VMD). It is provided for informational purposes only and does not replace professional veterinary advice. Always consult your vet before administering any medication.

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