Enovex 0.5% w/v Pour-on Solution for Cattle

Do not treat cattle when their hair or hide is wet. Do not treat cattle if rain is expected,
as rain within 2 hours of treatment may reduce efficacy. Do not apply to areas of skin
which have mange, scabs or other lesions or to areas contaminated with mud or
manure.
Care should be taken to avoid the following practices because they increase the risk of
development of resistance and could ultimately result in ineffective therapy:
•
extended period of time.
•
misadministration of the product, or lack of calibration of the dosing device (if
any).
Suspected clinical cases of resistance to anthelmintics should be further investigated
using appropriate tests (e.g. Faecal Egg Count Reduction Test). Where the results of
the test(s) strongly suggest resistance to a particular anthelmintic, an anthelmintic
belonging to another pharmacological class and having a different mode of action
should be used.
Resistance to ivermectin (an avermectin) has been reported in Cooperia onocophora in
cattle within the EU, in Teladorsagia in cattle in developed countries such as New
Zealand and Haemonochus in cattle outside the EU.

Amended pages: March 2025
AN: 02204/2022
Therefore the use of this product should be based on local (regional, farm)
epidemiological information about susceptibility of nematodes and recommendations on
how to limit further selection for resistance to anthelmintics.

Cases of intolerance with fatal outcome are reported in dogs, especially Collies, old
English Sheepdogs and related breeds or crosses, and also in turtles/tortoises.” Do not
allow these species to come in contact with this product.
Close container after use.
Special precautions for use in animals
As Ivermectin is extremely dangerous to fish and aquatic life, treated animals should not
have direct access to surface water and ditches during treatment.
To avoid secondary reactions due to the death of Hypoderma larvae in the oesophagus
or in the spine, it is recommended to administer the product at the end of warble fly
activity and before the larvae reach their resting sites.
It is recommended to treat all animals within a herd or group.
The shedding of nematode eggs can continue for some time after treatment.
Special precautions to be taken by the person administering the veterinary medicinal
product to animals
HIGHLY FLAMMABLE, keep away from heat, sparks, open flame or other sources of
ignition.
Use only in well ventilated areas or outdoors.
Do not smoke, eat or drink while handling the product.
May be irritating to human skin and eyes and the user should be careful not to apply it
to himself or other persons.
Operators should wear rubber gloves, boots, goggles and a waterproof coat when
applying the product. Protective clothing should be washed after use.
As absorption through skin can occur, in the event of accidental skin contact, wash the
affected area immediately with soap and water.
If accidental eye exposure occurs, flush the eyes immediately with water and get
medical attention.
Wash hands after use.