Eficur 50 mg/ml Suspension for Injection for Pigs and Cattle
Active ingredient: Ceftiofur
Form
Injection
Species
Manufacturer
Laboratorios Hipra SA
VMD MA No.
17533/5027
What it's used for
Infections associated with bacteria sensitive to ceftiofur: Pigs: - Treatment of bacterial respiratory disease associated with multocida, and Streptococcus...
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Prescription required
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Eficur 50 mg/ml Suspension for Injection for Pigs and Cattle — SPC Details
Source: VMD Summary of Product Characteristics (SPC). Last updated 26 Mar 2026.
Pigs:
- Treatment of bacterial respiratory disease associated with
multocida, and Streptococcus suis.
Cattle:
- For the treatment of bacterial respiratory disease associated with
haemolytica, Pasteurella multocida and Histophilus somni.
- For the treatment of acute interdigital necrobacillosis (panaritium, foot rot)
associated with and
(Porphyromonas asaccharolytica).
- For the treatment of the bacterial component of acute post-partum (puerperal)
metritis within 10 days after calving associated with Escherichia coli,
Arcanobacterium pyogenes
cases where treatment with another antimicrobial has failed).
Revised: November 2025
MA split from NI MA following AN: 00096/2025
3 mg ceftiofur/kg bw/day for 3 days by intramuscular injection, i.e. 1 ml of the
product /16 kg bw/day.
Cattle:
Treatment of respiratory disease: 1 mg ceftiofur/kg bw/day for 3 to 5 days by
subcutaneous injection, i.e. 1 ml of the product /50 kg bw/day.
Treatment of acute interdigital necrobacillosis: 1 mg ceftiofur/kg bw/day for 3
days by subcutaneous injection, i.e. 1 ml of the product/50 kg bw/day.
Acute post-partum metritis within 10 days after calving: 1 mg ceftiofur/kg
bw/day for 5 consecutive days by subcutaneous injection, i.e. 1 ml of the
product /50 kg bw/day.
Subsequent injections must be given at different sites.
In case of acute post-partum metritis, additional supportive therapy might be
required in some cases.
To ensure a correct dosage, body weight should be determined as accurately
as possible to avoid underdosing.
Shake well before use.
Revised: November 2025
MA split from NI MA following AN: 00096/2025
and other -lactam antibiotics.
Do not inject intravenously.
Do not use in poultry (including eggs) due to risk of spread of antimicrobial
resistance to humans.
skin reactions, anaphylaxia) may occasionally occur.
In pigs, mild reactions at the injection site, such as discoloration of the fascia or
fat, have been observed in some animals for up to 20 days after injection.
In cattle, mild inflammatory reactions at the injection site, such as tissue
oedema and discoloration of the subcutaneous tissue and/or fascial surface of
the muscle may be observed. Clinical resolution is reached in most animals by
10 days after injection although slight tissue discoloration may persist for 28
days or more.
Special precautions for use in animals
Shake the bottle well before use to bring the product back into suspension.
In case of the occurrence of allergic reaction the treatment should be
withdrawn.
Ceftiofur selects for resistant strains such as bacteria carrying extended
spectrum betalactamases (ESBL) and may constitute a risk to human health if
these strains disseminate to humans e.g. via food. For this reason, ceftiofur
should be reserved for the treatment of clinical conditions which have
responded poorly, or are expected to respond poorly (refers to very acute cases
when treatment must be initiated without bacteriological diagnosis) to first line
treatment. Official, national and regional antimicrobial policies should be taken
into account when the product is used. Increased use, including use of the
product deviating from the instructions given in the SPC, may increase the
prevalence of such resistance. Whenever possible, ceftiofur should only be
based on susceptibility testing.
Ceftiofur is intended for treatment of individual animals. Do not use for disease
prevention or as a part of heard health programmes. Treatment of groups of
animals should be strictly restricted to ongoing disease outbreaks according to
the approved conditions of use (see section 4.2 Indications for use, specifying
the target species).
Do not use as prophylaxis in case of retained placenta.
Special precautions to be taken by the person administering the veterinary
medicinal product to animals
Penicillins and cephalosporins may cause hypersensitivity (allergy) following
injection, inhalation, ingestion or skin contact. Hypersensitivity to penicillins may
lead to cross reactions to cephalosporins and vice versa. Allergic reactions to
these substances may occasionally be serious.
People with known hypersensitivity to penicillins or cephalosporins should avoid
contact with the product.
In the case of accidental self-injection or following exposure, if you develop
symptoms such as a skin rash, seek medical advice immediately and show the
package leaflet or the label to the physician.
Swelling of the face, lips or eyes or difficulty with breathing are more serious
symptoms and require urgent medical attention.
Revised: November 2025
MA split from NI MA following AN: 00096/2025
The bactericidal properties of –lactams are neutralised by simultaneous use of
bacteriostatic antibiotics (macrolides, sulphonamides and tetracyclines).
- Meat and offal: 5 days.
Cattle:
- Meat and offal: 8 days
- Milk: zero days.
5.
This information is sourced from the official Summary of Product Characteristics (SPC) published by the Veterinary Medicines Directorate (VMD). It is provided for informational purposes only and does not replace professional veterinary advice. Always consult your vet before administering any medication.
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Related Conditions
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Cemay 50 mg/ml Suspension for Injection for Pigs and Cattle
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