Ectoline Duo 100 mg / 120 mg Spot-on Solution for Very Large Cats

Wetting of the haircoat with water 2 hours before product application and twice during
the claimed period of efficacy against fleas (at two week intervals against adult fleas
or four week intervals against developing flea stages) was investigated during two
laboratory studies. Wetting of the haircoat with water as described did not adversely
affect product effectiveness.
The impact of shampooing on product effectiveness has not been investigated. If a cat
requires shampooing it is recommended that this is done before applying the
veterinary medicinal product.
At the beginning of the control measures, in the case of an infestation, the animal's
basket, bedding and regular resting areas such as carpets and soft furnishings should
be treated, with a suitable insecticide and vacuumed regularly.
To reduce environmental flea challenge, all animals living in the same household
should also be treated with a suitable flea control product.
The product does not prevent ticks from attaching to animals. If the animal has been
treated prior to exposure to the ticks, the ticks will be killed within 48 hours after
attachment. This will usually be prior to engorgement, minimising but not excluding the
risk of transmission of diseases.
Once dead, ticks will often drop off the animal. Any remaining ticks should be carefully
removed, ensuring that their mouth parts are not left within the skin.

Special precautions for use in animals:
For external use only. Do not administer orally.
Animals should be weighed accurately prior to treatment.
The safety of the product has not been established in cats younger than 10 weeks of
age or in cats weighing less than 1.0 kg.
Avoid contact with the animal’s eyes. In the case of accidental eye contact, flush the
eyes with water.
Care should be taken to apply the product correctly as described under section 4.9.
Do not apply the product on wounds or damaged skin. It is important to make sure
that the veterinary medicinal product is applied directly onto an area of dry skin
where the animal cannot lick it off and to make sure that animals do not lick each
other following treatment.
Consult your veterinary surgeon before using the product if your cat is unwell or
currently receiving any other veterinary treatment.
Inform your veterinary surgeon that you are using this product if s/he provides your cat
with any other medication.

Revised: June 2025
AN: 00430/2025
Seek veterinary advice if the product is accidentally ingested or comes into contact
with your animal’s eyes.
The use of the product has not been studied in sick or debilitated cats.
In the absence of additional safety studies, do not repeat the treatment at intervals of
less than 4 weeks.
Special precautions to be taken by the person administering the veterinary medicinal
product to animals:
The product may cause neurotoxicity.
The product may be harmful if swallowed.
Avoid ingestion including hand-to-mouth contact.
Do not smoke, drink or eat during application.
In the event of accidental ingestion, seek medical advice immediately and show the
package leaflet or the label to the physician.
This product can cause eye and mucous membrane irritation.
Avoid contact with skin, eye and mouth, including hand to eye contact.
In the case of accidental skin or eye contact, immediately and thoroughly flush with
water. If skin or eye irritation persists, seek medical advice and show the package
leaflet or the label to the physician.
Wash hands after use.
Treated animals should not be handled until the application site is dry, and children
should not be allowed to play with treated animals until the application site is dry. It is
therefore recommended that animals are not treated during the day, but should be
treated during the early evening, and that recently treated animals should not be
allowed to sleep with owners, especially children.
Keep the pipettes in the original packaging until ready for use and dispose of used
pipettes immediately.
Other precautions
The product may have adverse effects on painted, varnished or other household
surfaces or furnishings. Allow the application site to dry before permitting contact with
such materials.