DIXIE 268 mg Spot-on Solution for Large Dogs

The product does not prevent ticks from attaching to the animals. Therefore, the
transmission of infectious diseases by ticks cannot be excluded. There is no data
available on the effect of bath / shampoo on the efficacy of the veterinary drug in dogs.
Bathing / shampoo applied before or often after treatment may reduce the
effectiveness of the product.
Fleas from pets often infest the animal's basket, bedding and regular resting areas
such as carpets and soft furnishings which should be treated, in case of massive
infestation and at the beginning of the control measures, with a suitable insecticide and
vacuumed regularly.
When used as part of a strategy for the treatment of Flea Allergy Dermatitis, monthly
applications to the allergic patient and to other dogs in the household are
recommended.
To reduce re-infestation from emergence of new fleas, it is recommended that all dogs
in a household be treated. Other animals living in the same household should also be
treated with a suitable product.
The product will prevent new tick infestations from day 9 to day 23 after application of
the product. Considering that it takes 9 days to reach sufficient efficacy, there may be
gaps in the prevention of re-infestations after subsequent applications of the product.

Special precautions for use in animals
For external use only. Do not apply the product on wounds or damaged skin.
Avoid contact with the animal’s eyes. In case of accidental eye contact immediately
and thoroughly flush the eyes with water.

Animals should be weighed accurately prior to treatment (see section 4.3).
It is important to make sure that the product is applied to an area where the animal
cannot lick it off, and to make sure that animals do not lick each other following
treatment.

Revised: November 2023
AN: 02034/2023
The potential toxicity of the product for puppies less than 8 weeks of age in contact
with a treated bitch is not documented. Special care should be taken in this case.
Special precautions to be taken by the person administering the veterinary medicinal
product to animals
This product may cause neurotoxicity. Keep stored pipettes in the original packaging
until ready to use. In order to prevent children from getting access to used pipettes,
dispose of used pipettes immediately.
People with a known hypersensitivity to fipronil or any of the excipients should avoid
contact with the veterinary medicinal product.
This product can cause mucous membrane and eye irritation. Therefore, contact of the
product with mouth and eyes should be avoided. In case of accidental ocular exposure
or irritation of the eyes during administration, these should be rinsed immediately and
thoroughly with plain water. If eye irritation persists, seek medical advice immediately
and show the package leaflet or the label to the physician.
Avoid contents coming into contact with the fingers. In case of dermal exposure, wash
immediately with soap and water.
Wash hands after use.
Do not smoke, drink or eat during application.
Treated animals should not be handled, and children should not be allowed to play
with them until the application site is dry. It is therefore recommended that animals are
not treated during the day, but should be treated during the early evening, and that
recently treated animals should not be allowed to sleep with owners, especially
children.
Other precautions
Fipronil may adversely affect aquatic organisms. Dogs should not be allowed to swim
in watercourses for 2 days after application.