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NFA-VPS Over the Counter Companion Animal

Bob Martin Fipronil 402 mg Spot-on Solution for Extra Large Dogs

Active ingredient: Fipronil

Form

Spot-on

Species

Dogs

Manufacturer

Pets Choice Healthcare Limited

VMD MA No.

61560/3023

What it's used for

Treatment of flea (Ctenocephalides spp.) and tick (Rhipicephalus sanguineus and Ixodes ricinus) infestations. Fleas will be killed within 24 h. Insecticida...

Full indications, dosage and side effects ↓
View official SPC (PDF)

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Paying less for Fipronil

  1. 1

    Ask your vet for a written prescription

    They must provide one on request. Under the CMA Order the fee is capped at £21 from 2027.

  2. 2

    Fill it at a registered online retailer

    The CMA found online pharmacies 50–60% cheaper than practice dispensing on common medicines — typically £200–£300 a year.

Clinical information

Bob Martin Fipronil 402 mg Spot-on Solution for Extra Large Dogs — SPC Details

Source: VMD Summary of Product Characteristics (SPC). Last updated 26 Mar 2026.

Treatment of flea (Ctenocephalides spp.) and tick (Rhipicephalus sanguineus and
Ixodes ricinus) infestations.
Fleas will be killed within 24 h. Insecticidal efficacy against new infestations with adult
fleas persists for 8 weeks.
The product has a persistent acaricidal efficacy for 4 weeks against ticks
(Rhipicephalus sanguineus, Ixodes ricinus, Dermacentor reticulatus).
Ticks will usually be killed within 48 h after contact with Fipronil. However, if ticks of
some species (Dermacentor reticulatus) are already present when the product is
applied, all of the ticks may not be killed within the first 48 hours.
The product can be used as part of a treatment strategy for the control of Flea Allergy
Dermatitis (FAD), where this has been previously diagnosed by a veterinary surgeon.

Revised: November 2025
AN: 02315/2025
Route of administration and dosage:
External use only. Administer by topical application to the skin according to the
bodyweight as follows: 1 pipette of 4.02 ml per dog weighing over 40 kg and up to 60
kg bodyweight.
For dogs over 60 kg, use two pipettes of 2.68 ml.
Method of administration:
Remove the pipette from the blister packaging. Hold the pipette in an upright position
and snap off the top section of the cap, thereby opening the pipette.
Part your dog’s coat until the skin is visible. Place the tip of the pipette directly
against the bared skin and squeeze gently. Empty approximately half the contents at
each of two points along the dog’s back, preferably at the base of the head and
between the shoulder blades. Squeeze the pipette several times to ensure dosing is
complete. Avoid applying the solution onto the fur and do not rub into the skin.
Application of the solution as directed minimises the possibility that the animal will lick
the solution off. Do not allow pets to lick each other after treatment.
Care should be taken to avoid excessive wetting of the hair with the product since
this will cause a sticky appearance of hairs at the treatment spot. However, should
this occur, it will usually disappear within 24-48 hours post application. Crystals may
be seen on the hair and slight scaling may occur within 24-48 hours after application.

Revised: November 2025
AN: 02315/2025
Treatment schedule:
For optimal control of flea and/or tick infestation the treatment schedule can be based
on the local epidemiological situation.
The minimum interval between two treatments is 4 weeks.
Do not use on puppies less than 2 months old and /or weighing less than 2kg. Do not
use on sick (e.g. systemic diseases, fever…) or convalescent animals.
Do not use in rabbits, as adverse reactions and even death could occur.
This product is specifically developed for dogs. Do not use in cats, as this could lead
to overdosing.
Do not use on animals with known hypersensitivity to the active substance or to any
of the excipients.
If licking occurs, a brief period of hypersalivation may be observed due mainly to the
nature of the carrier.
Among the extremely rare suspected adverse reactions, transient cutaneous
reactions on the application site (skin discoloration, local alopecia, pruritus,
erythema) and general pruritus or alopecia have been reported after use.
Exceptionally, hypersalivation, reversible neurologic symptoms (hyperesthesia,
depression, nervous symptoms), vomiting or respiratory symptoms have been
observed after use.
The frequency of adverse reactions is defined using the following convention:
- very common (more than 1 in 10 animals displaying adverse reactions during the
course of one treatment)
- common (more than 1 but less than 10 animals in 100 animals)
- uncommon (more than 1 but less than 10 animals in 1,000 animals)
- rare (more than 1 but less than 10 animals in 10,000 animals)
- very rare (less than 1 animal in 10,000 animals, including isolated reports).

Revised: November 2025
AN: 02315/2025
Avoid frequent swimming or shampooing the animal because the maintenance of
effectiveness of the product in these cases has not been tested.
The product does not prevent ticks from attaching to the animals. If the animal has
been treated prior to exposure to the ticks, the ticks will be killed in the first 24-48
hours after attachment. This will usually be prior to engorgement, minimising but not
excluding the risk of transmission of diseases. Once dead, ticks will often drop off
the animal, but any remaining ticks may be removed with a gentle twist.
Fleas from pets often infest the animal's basket, bedding and regular resting areas
such as carpets and soft furnishings which should be treated, in case of massive
infestation and at the beginning of the control measures, with a suitable insecticide
and vacuumed regularly.
For optimal control of flea infestation in multi-pet household, all dogs and cats in the
household should be treated with a suitable insecticide.
When used as part of a strategy for the treatment of Flea Allergy Dermatitis, monthly
applications to the allergic patient and to other dogs and cats in the household are
recommended.

i) Special precautions for use in animals
Animals should be weighed accurately prior to treatment.
Avoid contact with the animal’s eyes. In the case of accidental eye contact,
immediately and thoroughly flush the eyes with water.
It is important to make sure that the product is applied to an area where the animal
cannot lick it off, and to make sure that animals do not lick each other following
treatment.
Do not apply the product on wounds or damaged skin.

Revised: November 2025
AN: 02315/2025
ii) Special precautions to be taken by the person administering the
veterinary medicinal product to animals
This product can cause mucous membrane and eye irritation. Therefore, contact
between the product and the mouth or eyes should be avoided.
In the case of accidental eye contact, immediately and thoroughly flush the eyes with
water. If eye irritation persists seek medical advice and show the package leaflet or
the label to the physician.
Do not smoke, drink or eat during application.
Avoid contents coming into contact with the fingers. If this occurs, wash hands with
soap and water. Wash hands after use.
Animals or people with a known hypersensitivity to fipronil or any of the other
ingredients should avoid contact with the product.
Treated animals should not be handled until the application site is dry, and children
should not be allowed to play with treated animals until the application site is dry. It is
therefore recommended that animals are not treated during the day, but should be
treated during the early evening, and that recently treated animals should not be
allowed to sleep with owners, especially children.
Keep pipettes in the original packaging and dispose of used pipettes immediately.
iii) Environmental warning
Fipronil may adversely affect aquatic organisms. Dogs should not be allowed to swim
in water courses for 2 days after application.
iv) Other precautions
The product may have adverse effects on painted, varnished or other household
surfaces or furnishings.
None known.
Store below 25C, in a dry place in the original packaging.
Not applicable.
5.

This information is sourced from the official Summary of Product Characteristics (SPC) published by the Veterinary Medicines Directorate (VMD). It is provided for informational purposes only and does not replace professional veterinary advice. Always consult your vet before administering any medication.

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