Bimectin 18.7 mg/g Oral Paste for Horses

Revised: November 2021
AN: 00980/2021Page 4 of 6
4.8 Interaction with other medicinal products and other forms of
interaction
The effects of GABA agonists are increased by ivermectin.
4.9 Amounts to be administered and administration route
Administer orally as a single dose rate to horses at the recommended dose level
of 0.2mg ivermectin per kilogram of bodyweight. The smaller syringe delivers
120mg ivermectin, sufficient to treat 600kg of bodyweight. The bigger syringe
delivers 160mg ivermectin, sufficient to treat 800kg of bodyweight.
To ensure administration of the correct dose, body weight should be determined
as accurately as possible.
If animals are to be treated collectively rather than individually, they should be
grouped according to their bodyweight and dosed accordingly, in order to avoid
under- or over-dosing.
This is a single dose product. Discard after use.
Dosing Instructions:
Each weight marking on the syringe plunger will deliver sufficient paste to treat
100kg bodyweight. Unlock the knurled ring by making ¼ turn and slide the
knurled ring up the plunger shaft so that the side nearest the barrel is at the
prescribed weight marking. Turn the knurled ring ¼ turn to lock in place. Make
sure the horse’s mouth contains no feed. Remove the plastic cap from the tip of
the nozzle. Insert the syringe into the horse’s mouth at the interdental space.
Advance the plunger as far as it will go, depositing the medication on the base of
the tongue. Immediately raise the horse’s head for a few seconds after dosing.
The treatment schedule should be based on the local epidemiological situation.
4.10 Overdose (symptoms, emergency procedures, antidotes), if
necessary
Mild transitory signs (slowed pupillary light response and depression) have been
seen at a dose of 1.8mg/kg (9 times the recommended dose level). Other signs
seen at higher doses includes mydriasis, ataxia, tremors, stupor, coma and
death. The less severe signs have been transitory. No antidote has been
identified; however, symptomatic therapy may be beneficial.
4.11 Withdrawal period(s)
Meat and offal: 34 days.
Do not use in mares producing milk for human consumption.
5.