Animec 18.7 mg/g Oral Paste for Horses

Some horses with heavy infections of Onchocerca spp. microfilariae have
experienced oedema and pruritus following treatment, such reactions are
assumed to be the result of death of large numbers of microfilariae. These signs
resolve within a few days but symptomatic treatment may be advisable.
Care should be taken to avoid the following practices because they increase the
risk of development of resistance and could ultimately result in ineffective therapy:
•
an extended period of time,
•
misadministration of the product.
Suspected clinical cases of resistance to anthelmintics should be further
investigated using appropriate tests (e.g. Faecal Egg Count Reduction Test).
Where the results of the test(s) strongly suggest resistance to a particular
anthelmintic, an anthelmintic belonging to another pharmacological class and
having a different mode of action should be used.
Veterinary advice should be given on appropriate dosing programs and stock
management to achieve adequate parasite control and reduce the likelihood of
anthelmintic resistance developing. In the event that a product is suspected of
being ineffective, the animal owner is advised to seek veterinary advice.
Resistance to ivermectin has been reported in Parascaris equorum. Therefore, the
use of this product should be based on local farm epidemiological information
about susceptibility of nematodes and recommendations on how to limit further
selection for resistance to anthelmintics

i. Special precautions for use in animals
Since ivermectin is highly bound to plasma proteins, special care should be
taken in cases of sick animals or in nutritional conditions associated with
low plasma protein levels.
Dogs and cats should not be allowed to ingest spilled gel or have access to
used packaging due to the potential for adverse effects related to
ivermectin toxicity

Revised: August 2025
AN: 01416/2025Page 3 of 6
The product has been formulated for use in horses only. Cats, dogs
(especially Collies, Old English Sheepdogs and related breeds or crosses)
and also turtles and tortoises may be adversely affected by the
concentration of ivermectin in this product if they are allowed to ingest
spilled paste or have access to used syringes.
ii. Special precautions to be taken by the person administering the veterinary
medicinal product to animals
Do not smoke, eat or drink while handling the product.
Wash hands after use.
This product may cause skin and eye irritation. Therefore, the user should
avoid contact of the product with the skin and the eyes. In case of contact,
rinse immediately with plenty of water.
In the case of accidental ingestion or eye irritation after contact seek
medical advice immediately and show the package insert or the label to the
physician