Amflee 268 mg Spot-on Solution for Large Dogs

Bathing/immersion in water within two days after application of the veterinary
medicinal product should be avoided. After weekly immersions in water for one
minute the period of persistent insecticidal efficacy against fleas was 7 weeks.
The veterinary medicinal product does not prevent ticks from attaching to the
animals. If the animal has been treated prior to exposure to the ticks, the ticks will be
killed in the first 24-48 hours after attachment. This will usually be prior to
engorgement, minimising but not excluding the risk of transmission of diseases.
Once dead, ticks will often drop off the animal, but any remaining ticks may be
removed with a gentle pull.
Fleas from pets often infest the animal's basket, bedding and regular resting areas
such as carpets and soft furnishings which should be treated, in case of massive
infestation and at the beginning of the control measures, with a suitable insecticide
and vacuumed regularly.
When used as part of a strategy for the treatment of Flea Allergy Dermatitis, monthly
applications to the allergic patient and to other dogs and cats in the household are
recommended.
For optimal control of flea infestation in multi-pet household, all dogs and cats in the
household should be treated with a suitable insecticide.

Special precautions for safe use in the target species:
Avoid contact with the animal's eyes. In the case of accidental eye contact,
immediately and thoroughly flush the eyes with water.
It is important to make sure that the veterinary medicinal product is applied to an area
where the animal cannot lick it off and to make sure that animals do not lick each
other following treatment.
Do not apply the veterinary medicinal product on wounds or damaged skin.
AN: 00885/2025 & 00893/2025
Special precautions to be taken by the person administering the veterinary medicinal
product to animals:
This veterinary medicinal product can cause mucous membrane and eye irritation.
Therefore, contact between the veterinary medicinal product and the mouth or eyes
should be avoided.
In the case of accidental eye contact, immediately and thoroughly flush the eyes with
water. If eye irritation persists seek medical advice immediately and show the
package leaflet or the label to the physician.
Do not smoke, drink or eat during application.
Avoid contents coming into contact with the fingers. If this occurs, wash off
immediately with soap and water.
Wash hands after use.
People with known hypersensitivity to fipronil or dimethyl sulfoxide or other excipients
should avoid contact with the veterinary medicinal product.
Treated animals should not be handled until the application site is dry, and children
should not be allowed to play with treated animals until the application site is dry. It is
therefore recommended that animals are not treated during the day, but should be
treated during the early evening, and that recently treated animals should not be
allowed to sleep with owners, especially children.
Keep pipettes in original packaging and dispose of used pipettes immediately.
Special precautions for the protection of the environment:
Fipronil may adversely affect aquatic organisms. Dogs should not be allowed to swim
in water courses for 2 days after application.