Alfamed Fipronil 402 mg Spot-on Solution for Very Large Dogs

Shampooing an hour prior to treatment does not affect the efficacy of the veterinary
medicinal product against fleas.
Bathing/immersion in water within two days after application of the veterinary
medicinal product should be avoided. Weekly immersion in water for one minute
reduces the period of persistent insecticidal efficacy against fleas by one week and
therefore it is advisable to avoid frequent swimming and shampooing.
The veterinary medicinal product does not prevent ticks from attaching to the
animals. If the animal has been treated prior to exposure to the ticks, the ticks will be
killed in the first 24-48 hours after attachment. This will usually be prior to
engorgement, minimising but not excluding the risk of transmission of diseases.
Once dead, ticks will often drop off the animal, but any remaining ticks may be
removed with a gentle pull.
Fleas from pets often infest the animal's basket, bedding and regular resting areas
such as carpets and soft furnishings which should be treated, in case of massive
infestation and at the beginning of the control measures, with a suitable insecticide
and vacuumed regularly.
When used as part of a strategy for the treatment of Flea Allergy Dermatitis, monthly
applications to the allergic patient and to other dogs in the household are
recommended.
For optimal control of flea infestation in multi-pet household, all dogs and cats in the
household should be treated with a suitable insecticide.

Special precautions for safe use in the target species:
Animals should be weighed accurately prior to treatment.
Avoid contact with the animal’s eyes. In case of accidental eye contact, immediately
and thoroughly flush the eyes with water.
It is important to make sure that the veterinary medicinal product is applied to an area
where the animal cannot lick it off and to make sure that animals do not lick each
other following treatment.
Do not apply the veterinary medicinal product on wounds or damaged skin.
Special precautions to be taken by the person administering the veterinary medicinal
product to animals:
This veterinary medicinal product can cause mucous membrane and eye irritation.
Therefore, contact between the veterinary medicinal product and the mouth or eyes
should be avoided.
In case of accidental eye contact, immediately and thoroughly flush the eyes with
water. If eye irritation persists seek medical advice immediately and show the
package leaflet or the label to the physician.
Do not smoke, drink or eat during application.
Avoid contents coming into contact with the fingers. If this occurs, wash hands with
soap and water. Wash hands after use.
People with known hypersensitivity to fipronil or excipients should avoid contact with
the veterinary medicinal product.
Treated animals should not be handled until the application site is dry, and children
should not be allowed to play with treated animals until the application site is dry. It is
therefore recommended that animals are not treated during the day, but should be
treated during the early evening, and that recently treated animals should not be
allowed to sleep with owners, especially children.
Special precautions for the protection of the environment:
Fipronil may adversely affect aquatic organisms. Dogs should not be allowed to swim
in water courses for 2 days after application.
Other precautions:
The veterinary medicinal product may have adverse effects on painted, varnished or
other household surfaces or furnishings.