Virbamec Super 10 mg/ml, 100 mg/ml Solution for Injection

Care should be taken to avoid the following practices because they increase the
risk of development of resistance and could ultimately result in ineffective
therapy:
•
extended period of time.
•
misadministration of the product, or lack of calibration of the dosing device (if
any).

Revised: April 2024
AN: 01199/2023 & 01201/2023Page 3 of 7
Suspected clinical cases of resistance to anthelmintics should be further
investigated using appropriate tests (e.g. Faecal Egg Count Reduction Test).
Where the results of the test(s) strongly suggest resistance to a particular
anthelmintic, an anthelmintic belonging to another pharmacological class and
having a different mode of action should be used”.
Resistance to macrocyclic lactones (which includes ivermectin) has been
reported in , in cattle within the EU.
Therefore the use of this product should be based on local (regional, farm)
epidemiological information about susceptibility of nematodes and
recommendations on how to limit further selection for resistance to
anthelmintics.

i) Special precautions for use in animals
Divide doses greater than 10 ml between two injection sites to reduce
occasional discomfort or site reaction.
The timing of treatment for the parasitic stages of warbles should be
chosen carefully. The best time to treat against infections with
is immediately after the end of the swarming of the warbles, before the
larvae cause damage in the body of the animal (October to November). If
larvae of
this may induce posterior paralysis and recumbency. These reactions
occur mainly when animals are treated between December and March.
Avermectins may not be well tolerated in non-target species. Cases of
intolerance resulting in fatalities have been reported in dogs, especially
collies, old English sheep dogs and related breeds or crosses and also in
turtles/tortoises.
ii) Special precautions to be taken by the person administering the
veterinary medicinal product to animals
Do not smoke, drink or eat while handling the product.
Wash hands after use.
Avoid contact with skin and eyes.
Take care to avoid self-administration, the product may cause irritation
and/or pain at the site of injection. In case of accidental self-injection,
seek medical advice and show the label to the doctor.
iii) Other precautions
Ivermectin is highly toxic to aquatic invertebrates. Treated cattle should
not have direct access to ponds, streams or ditches for 14 days after
treatment to avoid adverse effects on aquatic organisms.

Revised: April 2024
AN: 01199/2023 & 01201/2023Page 4 of 7