Ivomec Super Injection for Cattle (Ivermectin and Clorsulon)

Care should be taken to avoid the following practices because they increase the risk of
development of resistance and could ultimately result in ineffective therapy:
- Too frequent and repeated use of anthelmintics from the same class, over an extended
period of time.
- Underdosing, which may be due to underestimation of body weight, misadministration of
the product, or lack of calibration of the dosing device (if any).
AN: 02205/2023 & 01184/2023
Suspected clinical cases of resistance to anthelmintics should be further investigated using
appropriate tests (e.g. Faecal Egg Count Reduction Test). Where the results of the test(s)
strongly suggest resistance to a particular anthelmintic, an anthelmintic belonging to
another pharmacological class and having a different mode of action should be used.

Special precautions for safe use in the target species:
Divide doses greater than 10 ml between two injection sites to reduce occasional
discomfort or site reaction.
Frequent and repeated use may lead to the development of resistance.
The timing of treatment for the parasitic stages of warbles should be chosen carefully. The
best time to treat against infections with is immediately after the end of the
swarming of the warbles, before the larvae cause damage in the body of the animal
(October to November). If larvae of are killed during migration through
the spine, this may induce posterior paralysis and recumbency. These reactions occur
mainly when animals are treated between December and March.
Special precautions to be taken by the person administering the veterinary medicinal
product to animals:
In case of accidental self-injection, seek medical advice immediately and show the
package leaflet or the label to the physician.
Do not smoke, drink or eat while handling the product.
Wash hands after use.
Avoid contact with skin and eyes.
Take care to avoid self-administration, the product may cause irritation and/or pain at the
site of injection.
Special precautions for the protection of the environment:
Not applicable.
Other precautions:
Avermectins may not be well tolerated in non-target species. Cases of intolerance
resulting in fatalities have been reported in dogs, especially Collies, Old English Sheep
Dogs and related breeds or crosses, and also in turtles/tortoises.