Maximec Plus 10 mg/ml + 100 mg/ml Solution for Injection for Cattle

For use only in beef cattle and non-lactating dairy cattle
Care should be taken to avoid the following practices because they increase the risk
of development of resistance and could ultimately result in ineffective therapy:
Too frequent and repeated use of anthelmintics from the same class, over an
extended period of time.
Underdosing, which may be due to underestimation of bodyweight, misadministration
of the product, or lack of calibration of the dosing device (if any).
Suspected clinical cases of resistance to anthelmintics should be further investigated
using appropriate tests (e.g. Faecal Egg Count Reduction Test). Where the results of
the test(s) strongly suggest resistance to a particular anthelmintic, an anthelmintic
belonging to another pharmacological class and having a different mode of action
should be used.
Resistance to macrocyclic lactones (which includes ivermectin) has been reported in
Ostertagia ostertagi and Cooperia species in cattle within the EU. Therefore, the use
of this product should be based on local (regional, farm) epidemiological information
about susceptibility of these helminth species and recommendations on how to limit
further selection for resistance to anthelmintics.

Special precautions for use in animals
This product does not contain any antimicrobial preservative.
Swab septum before removing each dose.
Special precautions to be taken by the person administering the veterinary medicinal
product to animals
This product may cause eye and skin irritation.
Avoid contact with skin or eyes.
In case of skin or eye contact, wash exposed area with plenty of clean water. If
symptoms persist, seek medical advice.
Do not eat or smoke while handling the product.
Take care to avoid accidental self-injection: the product may cause local irritation
and/or pain at the site of injection.
In case of accidental self-injection, seek immediate medical advice and show the
information leaflet or the label to the physician.
Wash hands after use.

Unlimited Renewal: May 2024
AN: 03561/2023 + 03700/2023
Other precautions
Ivermectin is highly toxic to aquatic organisms, dung beetles and sediment dwelling
insects. Long-term effects on dung insects caused by continuous or repeated use
cannot be excluded.
The risk to aquatic ecosystems and dung fauna can be reduced by avoiding too
frequent and repeated use of ivermectin and products of the same anthelmintic class
in cattle, sheep and pigs.
Therefore, the repetition of treatment in a pasture during a season should be
performed only in the absence of alternative treatment and on veterinary advice.
Treated cattle should not have direct access to ponds, streams or ditches for 14 days
after treatment.