Taurador 5 mg/ml Pour-on Solution for Cattle

For external use only.

Revised: February 2019
AN: 02494/2017
Care should be taken to avoid the following practices because they increase
the risk of development of resistance and could ultimately result in
ineffective therapy:
- too frequent and repeated use of anthelmintics from the same class, over
an extended period of time.
- under dosing, which may be due to underestimation of bodyweight,
misadministration of the product, or lack of calibration of a dosing device (if
any).
Resistance to doramectin and other avermectins has been reported in
gastro-intestinal nematodes, especially
ostertagi, in cattle. Therefore, the use of this product should be based on
local (regional, farm) epidemiological information about susceptibility of the
target nematodes and recommendations on how to limit further selection for
resistance to anthelmintics.
Suspected clinical cases of resistance to anthelmintics should be further
investigated using appropriate tests (e.g. faecal egg count reduction test).
Where the results of the test(s) strongly suggest resistance to a particular
anthelmintic, an anthelmintic belonging to a different pharmacological class
and having a different mode of action should be used.
Do not apply to areas of skin that are contaminated with mud or manure.
Therapeutic efficacy for internal and external parasites is not affected by
heavy rainfall (2 cm in 1 hour) either before (20 minutes) or after (20 and 40
minutes) treatment. The influence of extreme weather conditions on efficacy
is unknown.

i. Special precautions for use in animals.
Avermectins may not be well tolerated in all non-target species. Cases of
intolerance with fatal outcome have been reported in dogs, especially
Collies, old English Sheepdogs and related breeds or crosses, and also in
chelonia (turtles andtortoises). Care should be taken to avoid ingestion of
spilled product or access to containers by these other species.
To avoid secondary reactions due to death of larvae in the
oesophagus or the spine, it is recommended to administer the veterinary
product at the end of the period of warble fly activity and before the larvae
reach their resting sites. Consult your veterinary surgeon on the correct
timing of treatment.
ii. Special precautions to be taken by the person administering the
veterinary medicinal product to animals.

Revised: February 2019
AN: 02494/2017
Persons with known hypersensitivity to the active substance should avoid
contact with the product. Do not smoke or eat while handling the product.
Wash hands after use. The veterinary product may be irritating to human
skin and eyes and users should be careful not to apply it to themselves or to
other persons. Operators should wear rubber gloves and boots with a
waterproof coat when applying the product. Protective clothing should be
washed after use. If accidental skin contact occurs, wash the affected area
immediately with soap and water. If accidental eye exposure occurs, flush
the eyes immediately with water and get medical attention. Use only in well
ventilated areas or outdoors.
Highly Flammable - Keep away from heat, sparks, open flame or other
sources of ignition.
iii. Other precautions
Doramectin is very toxic to dung fauna and aquatic organisms and may
accumulate in sediments.
The risk to aquatic ecosystems and dung fauna can be reduced by avoiding
too frequent and repeated use of doramectin (and products of the same
anthelmintic class) in cattle and sheep.
The risk to aquatic ecosystems will be further reduced by keeping treated
cattle away from water bodies for two to five weeks after treatment