Dectomax 5 mg/ml Pour-on Solution for Cattle

For external use only.
Care should be taken to avoid the following practices because they increase the
risk of development of resistance and could ultimately result in ineffective therapy:
- too frequent and repeated use of anthelmintics from the same class, over an
extended period of time.
- under dosing, which may be due to underestimation of bodyweight,
misadministration of the product, or lack of calibration of a dosing device (if any).
Resistance to doramectin and other avermectins has been reported in gastro-
intestinal nematodes, especially Cooperia oncophera and Ostertagia ostertagi
in cattle. Therefore, the use of this product should be based on local (regional,
farm) epidemiological information about susceptibility of the target nematodes
and recommendations on how to limit further selection for resistance to
anthelmintics.
Suspected clinical cases of resistance to anthelmintics should be further
investigated using appropriate tests (e.g. faecal egg count reduction test). Where
the results of the test(s) strongly suggest resistance to a particular anthelmintic,
an anthelmintic belonging to a different pharmacological class and having a
different mode of action should be used.
Do not apply to areas of skin that are contaminated with mud or manure.
Therapeutic efficacy for internal and external parasites is not affected by heavy
rainfall (2 cm in 1 hour) either before (20 minutes) or after (20 and 40 minutes)
treatment. The influence of extreme weather conditions on efficacy is unknown.

Special precautions for use in animals
Avermectins may not be well tolerated in all non-target species. Cases of
intolerance with fatal outcome are reported in dogs, especially Collies, old English
Sheepdogs and related breeds or crosses, and also in turtles/tortoise. Care
should be taken to avoid ingestion of spilled product or access to containers by
these other species.
To avoid secondary reactions due to death of Hypoderma
oesophagus or the spine, it is recommended to administer the product at the end
of the period of warble fly activity and before the larvae reach their resting sites.
Consult your veterinary surgeon on the correct timing of treatment.
Disease associated with warble fly is notifiable in some regions.

Issued: August 2023
AN: 02094/2022
Special precautions to be taken by the person administering the veterinary
medicinal product to animals
People with known hypersensitivity to the doramectin should avoid contact with
the product. Do not smoke or eat while handling the product. Wash hands after
use. The product may be irritating to human skin and eyes and users should be
careful not to apply it to themselves or to other people. Operators should wear
impermeable rubber gloves and boots with a waterproof coat when applying the
product. Protective clothing should be washed after every use. If accidental skin
contact occurs, wash the affected area immediately with soap and water. If
irritation persists, seek medical attention. If accidental eye exposure occurs, flush
the eyes immediately with clean water and seek medical attention immediately.
Avoid accidental inhalation of this product, as this may cause drowsiness and
dizziness. Use only in well ventilated areas or outdoors.
Highly Flammable - Keep away from heat, sparks, open flame or other sources
of ignition.
Special precautions for the protection of the environment
Doramectin is very toxic to dung fauna and aquatic organisms and may
accumulate in sediments.
The risk to aquatic ecosystems and dung fauna can be reduced by avoiding too
frequent and repeated use of doramectin (and products of the same anthelmintic
class) in cattle.
The risk to aquatic ecosystems will be reduced by keeping treated cattle away
from water bodies for five weeks after treatment.
Other precautions
Not applicable