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POM-V Prescription Required

Sureseal 2.6 g Intramammary Suspension for Cattle

Active ingredient: Bismuth Subnitrate

Form

Intramammary

Species

Cattle

Manufacturer

Norbrook Laboratories Limited

VMD MA No.

02000/5024

What it's used for

In cows considered likely to be free of sub-clinical mastitis, the veterinary medicinal product may be suitable for use on its own in dry cow management fo...

Full indications, dosage and side effects ↓
View official SPC (PDF)

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Paying less for Bismuth Subnitrate

  1. 1

    Ask your vet for a written prescription

    They must provide one on request. Under the CMA Order the fee is capped at £21 from 2027.

  2. 2

    Fill it at a registered online retailer

    The CMA found online pharmacies 50–60% cheaper than practice dispensing on common medicines — typically £200–£300 a year.

Prescription required

Your vet must provide a written prescription on request. You can then purchase from any licensed online retailer.

Clinical information

Sureseal 2.6 g Intramammary Suspension for Cattle — SPC Details

Source: VMD Summary of Product Characteristics (SPC). Last updated 27 Mar 2026.

In cows considered likely to be free of sub-clinical mastitis, the veterinary medicinal
product may be suitable for use on its own in dry cow management for mastitis control.
Selection of cows for treatment with the veterinary medicinal product should be based
on veterinary clinical judgement. Selection criteria may be based on the mastitis and
cell count history of individual cows, or recognised tests for the detection of sub-clinical
mastitis such as bacteriological sampling.
Infuse the content of one syringe of the veterinary medicinal product into each udder
quarter immediately after the last milking of the lactation (at drying off). Do not
massage the teat or udder after infusion of the product.
Care must be taken not to introduce pathogens into the teat in order to reduce the risk
of post-infusion mastitis (aseptic technique).
It is essential that the teat is thoroughly cleaned and disinfected, with surgical spirit or
alcohol-impregnated wipes. The teats should be wiped until the wipes are no longer
visibly dirty. Teats should be allowed to dry prior to infusion. Infuse aseptically and
avoid contamination of the syringe nozzle. Following infusion it is advisable to use an
appropriate teat dip or spray.
Under cold conditions the veterinary medicinal product may be warmed to room
temperature in a warm environment to aid syringeability.
See section 3.7. Do not use in lactating cows. Do not use the veterinary medicinal
product alone in cows with sub-clinical mastitis at drying off. Do not use in cows with
clinical mastitis at drying off.
Do not use in cases of hypersensitivity to the active substance or to any of the
excipients.
Very rare
(<1 animal / 10,000 animals treated,
including isolated reports):
Acute mastitis
1
Primarily due to the poor infusion technique and lack of hygiene. See sections 3.5
and 3.9 regarding the importance of aseptic technique.
Reporting adverse events is important. It allows continuous safety monitoring of a
veterinary medicinal product. Reports should be sent, preferably via a veterinarian, to
either the marketing authorisation holder or its local representative or the national
competent authority via the national reporting system. See the package leaflet for
respective contact details.
None.

Special precautions for safe use in the target species
It is good practice to observe dry cows regularly for signs of clinical mastitis. If a
sealed quarter develops clinical mastitis, the affected quarter should be stripped out
manually before appropriate therapy is instituted.
To reduce the risk of contamination, do not immerse the syringe in water.
Use the syringe only once
Since the veterinary medicinal product does not have antimicrobial activity, in order to
minimise the risk of acute mastitis due to poor infusion technique and lack of hygiene
(see section 3.6), it is crucial to follow the aseptic technique of administration
described in section 3.9.
Do not administer any other intramammary product following administration of the
veterinary medicinal product.
In cows that may have sub-clinical mastitis, the veterinary medicinal product may be
used following administration of a suitable dry cow antibiotic treatment to the infected
quarter.
Special precautions to be taken by the person administering the veterinary medicinal
product to animals
Avoid contact with skin or eyes.
Should skin or eye contact occur, wash the affected area thoroughly with water.
If irritation persists, seek medical advice and show the package leaflet or label to the
physician.
People with known hypersensitivity to the active substance should avoid contact with
the veterinary medicinal product.
Wash hands after use.
Special precautions for the protection of the environment:
Not applicable.
In clinical trials, the compatibility of the veterinary medicinal product has only been
shown with a cloxacillin-containing dry cow preparation.
This veterinary medicinal product does not require any special storage conditions.
Meat & offal: zero days.
Milk: zero hours.

This information is sourced from the official Summary of Product Characteristics (SPC) published by the Veterinary Medicines Directorate (VMD). It is provided for informational purposes only and does not replace professional veterinary advice. Always consult your vet before administering any medication.

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