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POM-V Prescription Required

Cepralock 2.6 g Intramammary Suspension for Dry Cows

Active ingredient: Bismuth Subnitrate

Form

Intramammary

Species

Cattle

Manufacturer

Intervet International B.V.

VMD MA No.

06376/5048

What it's used for

In cows considered likely to be free of sub-clinical mastitis, the veterinary medicinal product can be used on its own in dry cow management and mastitis c...

Full indications, dosage and side effects ↓
View official SPC (PDF)

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Paying less for Bismuth Subnitrate

  1. 1

    Ask your vet for a written prescription

    They must provide one on request. Under the CMA Order the fee is capped at £21 from 2027.

  2. 2

    Fill it at a registered online retailer

    The CMA found online pharmacies 50–60% cheaper than practice dispensing on common medicines — typically £200–£300 a year.

Prescription required

Your vet must provide a written prescription on request. You can then purchase from any licensed online retailer.

Clinical information

Cepralock 2.6 g Intramammary Suspension for Dry Cows — SPC Details

Source: VMD Summary of Product Characteristics (SPC). Last updated 27 Mar 2026.

In cows considered likely to be free of sub-clinical mastitis, the veterinary medicinal
product can be used on its own in dry cow management and mastitis control.
The veterinary medicinal product has a dual tip nozzle. The cap of the syringe can be
partially or fully removed. It is recommended to pinch the teat at the teat base as it
aids in positioning the paste in the teat cistern, sealing the teat canal from the top.
Short tip option: The short tip option allows for a partial insertion technique so that
the syringe only needs to be inserted in the teat end.
Long tip option: The long tip option may be used for treatment convenience for
example to prevent the tip from flipping out due to a moving or nervous cow.
Step 1: Removal of the breakable cap Step 2: Long or short tip insertion
Infuse the content of one syringe of the veterinary medicinal product into each udder
quarter immediately after the last milking of the lactation (at drying off). Do not
massage the teat or udder after infusion of the veterinary medicinal product because
it is important that the sealant stays in the teat itself and does not enter the udder.
Care must be taken not to introduce pathogens into the teat in order to reduce the
risk of post-infusion mastitis.
It is essential that the teat is thoroughly cleaned with the alcoholic disinfectant wipes
provided.
The teats should be wiped until there is no visible dirt collected on the wipe. Teats
should be allowed to dry prior to infusion. Infuse aseptically and take care to avoid
contamination of the syringe nozzle. Following infusion, it is advisable to use an
appropriate teat dip or spray.
Under cold conditions the veterinary medicinal product may be warmed to room
temperature in a warm environment, to aid syringeability.
Do not use the veterinary medicinal product alone in cows with sub-clinical mastitis at
drying off.
Do not use in cows with clinical mastitis at drying off.
Do not use in lactating cows. See section 3.7.
Do not use in cases of hypersensitivity to the active substance or to any of the
excipients.
None known.
Reporting adverse events is important. It allows continuous safety monitoring of a
veterinary medicinal product. Reports should be sent, preferably via a veterinarian, to
either the marketing authorisation holder or the national competent authority via the
national reporting system. See the package leaflet for respective contact details.
Selection of cows for treatment with the veterinary medicinal product should be
based on veterinary clinical judgement. Selection criteria may be based on the
mastitis and cell count history of individual cows, or recognized tests for the detection
of sub-clinical mastitis or bacteriological sampling.

Special precautions for safe use in the target species:
It is good practice to observe dry cows regularly for signs of clinical mastitis. If a
sealed quarter develops clinical mastitis, the affected quarter should be stripped out
manually before appropriate therapy is instituted.
To reduce the risk of contamination, do not immerse the syringe in water.
Use the syringe only once.
It is important to observe strict aseptic technique for the administration of the
veterinary medicinal product, because the veterinary medicinal product does not
have antimicrobial activity.
Do not administer any other intramammary product following administration of the
veterinary medicinal product.
In cows that may have sub-clinical mastitis, the veterinary medicinal product may be
used following administration of a suitable dry cow antibiotic treatment to the infected
quarter.
Special precautions to be taken by the person administering the veterinary medicinal
product to animals:
This veterinary medicinal product may cause skin and eye irritation. Avoid contact
with skin or eyes.
Should skin or eye contact occur, wash the affected area thoroughly with water.
Bismuth salts have been associated with hypersensitivity reactions. People with
known hypersensitivity to bismuth salts should avoid contact with the veterinary
medicinal product. If you develop symptoms following exposure, seek medical advice
and show the package leaflet or the label to the physician.
Wash hands after use.
Disinfectant wipes:
The disinfectant wipes may cause skin and eye irritation due to the presence of
isopropyl alcohol. Avoid eye contact. Avoid prolonged contact with skin. Avoid
inhalation of the vapour.
The wearing of gloves may prevent skin irritation.
Wash hands after use.
Special precautions for the protection of the environment:
Not applicable.
In clinical trials, the compatibility of a comparable teat seal formulation containing
bismuth subnitrate has only been shown with a cloxacillin-containing dry cow
preparation.
See also section 3.5.
This veterinary medicinal product does not require any special storage conditions.
Meat and offal: Zero days.
Milk: Zero hours.

This information is sourced from the official Summary of Product Characteristics (SPC) published by the Veterinary Medicines Directorate (VMD). It is provided for informational purposes only and does not replace professional veterinary advice. Always consult your vet before administering any medication.

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