Supremadex 10 mg/ml / 100 mg/ml Solution for Injection
Active ingredients: Clorsulon, Ivermectin
Form
Injection
Species
Manufacturer
Virbac
VMD MA No.
05653/5059
What it's used for
For the treatment of mixed trematode and nematode or arthropod infestations, due to adult and immature roundworms, lungworms, warbles, mites, lice and live...
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Prescription required
Your vet must provide a written prescription on request. You can then purchase from any licensed online retailer.
Supremadex 10 mg/ml / 100 mg/ml Solution for Injection — SPC Details
Source: VMD Summary of Product Characteristics (SPC). Last updated 26 Mar 2026.
to adult and immature roundworms, lungworms, warbles, mites, lice and liver fluke
in cattle.
Gastro-intestinal roundworms (adult and fourth-stage larvae):
Ostertagia ostertagi (including inhibited larval stages)
O. lyrata
Haemonchus placei
Trichostrongylus axei
Trichostrongylus colubriformis
Cooperia oncophora
Cooperia punctata
Cooperia pectinata
Bunostomum phlebotomum
Oesophagostomum radiatum
Strongyloides papillosus (adult)
Nematodirus helvetianus (adult)
Revised: July 2024
AN: 00683/2024
Nematodirus spathiger (adult)
Lungworms (adult and fourth-stage larvae):
Dictyocaulus
viviparus Liver fluke
(adult): Fasciola
hepatica
Warbles (parasitic stages):
Hypoderma bovis
Hypoderma
lineatum
Mange mites:
Psoroptes bovis
Sarcoptes scabiei var. bovis
Sucking lice:
Linognathus vituli
Haematopinus
eurysternus
The product may also be used as an aid in the control of the mange mite
Chorioptes bovis, but complete elimination may not occur.
dosage level of 200 mcg ivermectin and 2 mg clorsulon per kilogram of
bodyweight.
Each ml contains 10 mg of ivermectin and 100 mg of clorsulon, sufficient to treat
50 kg of bodyweight. Subcutaneous injection only.
To ensure administration of a correct dose, body weight should be determined as
accurately as possible.
Divide doses greater than 10 ml between two injection sites.
Inject under the loose skin behind the shoulder. Use of a 17 gauge, ½ inch (15-20
mm) needle is suggested. The injection may be given with any standard
automatic, multidose or single-dose hypodermic syringe. If using a hypodermic
syringe, use a separate sterile needle to withdraw the dose from the pack.
This product does not contain an antimicrobial preservative. Swab septum before
removing each dose. Use a dry, sterile needle and syringe.
For 200, 500 and 1000 ml pack sizes, use only automatic syringe
equipment. Injection on animals with wet or dirty hides is not
recommended.
When the temperature of the product is below 5°C, difficulty in administration may
be encountered due to increased viscosity. Warming the product and injection
equipment to about 15°C will greatly increase the ease with which the product can
be injected. Different injection sites should be used for other parenteral products.
The timing for treatment should be based on epidemiological factors and should
be customised for each individual farm. A dosing programme should be
established by the veterinary surgeon.
Do not use in non-lactating dairy cows including pregnant heifers within 60 days of
calving.
Not for use in species other than cattle as severe adverse reactions, including
fatalities, may occur in dogs for example.
Do not use by the intravenous or intramuscular route.
Do not use in animals known to be hypersensitive to the active substance.
administration. Soft-tissue swelling and/or slight pain at the injection site has also
been observed. These reactions have disappeared without treatment.
In case of hypersensitivity reactions a symptomatic treatment should be applied.
risk of development of resistance and could ultimately result in ineffective therapy:
- Too frequent and repeated use of anthelmintics from the same class, over
an extended period of time.
- Underdosing, which may be due to underestimation of body weight,
misadministration of the product, or lack of calibration of the dosing device (if
any).
Suspected clinical cases of resistance to anthelmintics should be further
investigated using appropriate tests (e.g. Faecal Egg Count Reduction
Test).
Revised: July 2024
AN: 00683/2024
Where the results of the test(s) strongly suggest resistance to a particular
anthelmintic, an anthelmintic belonging to another pharmacological class
and having a different mode of action should be used.
i. Special precautions for use in animals
Divide doses greater than 10 ml between two injection sites to reduce occasional
discomfort or site reaction.
Frequent and repeated use may lead to the development of resistance.
The timing of treatment for the parasitic stages of warbles should be chosen
carefully. The best time to treat against infections with
after the end of the swarming of the warbles, before the larvae cause damage in
the body of the animal (October to November). If larvae of
killed during migration through the spine, this may induce posterior paralysis and
recumbency. These reactions occur mainly when animals are treated between
December and March.
Avermectins may not be well tolerated in non-target species. Cases of intolerance
resulting in fatalities have been reported in dogs, especially Collies, Old English
Sheep Dogs and related breeds or crosses, and also in turtles/tortoises.
ii. Special precautions to be taken by the person administering the
veterinary medicinal product to animals
Do not smoke, drink or eat while handling the
product. Wash hands after use.
Avoid contact with skin and eyes.
Take care to avoid self-administration, the product may cause irritation and/or
pain at the site of injection.
Revised: July 2024
AN: 00683/2024
Store in the original container.
Following withdrawal of the first dose, use the product within 28 days.
consumption. Do not use in non-lactating dairy cows including pregnant heifers
within 60 days of calving.
5.
This information is sourced from the official Summary of Product Characteristics (SPC) published by the Veterinary Medicines Directorate (VMD). It is provided for informational purposes only and does not replace professional veterinary advice. Always consult your vet before administering any medication.
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Other Products Containing Clorsulon
These products share the same active ingredient and may be suitable alternatives. Always consult your vet.
Animec Super 10 mg/ml / 100 mg/ml Solution for Injection for Cattle
POM-VPSChanelle Pharmaceuticals Manufacturing Ltd
Animec Super 10 mg/ml / 100 mg/ml Solution for Injection for Cattle
POM-VPSChanelle Pharmaceuticals Manufacturing Ltd
Bimectin Plus, 10/100 mg/ml Solution for Injection for Cattle
POM-VPSBimeda Animal Health Limited
Ivermectin and Clorsulon 10 mg/ml / 100 mg/ml Solution for Injection for Cattle Virbac
POM-VPSVIRBAC
Ivomec Super Injection for Cattle (Ivermectin and Clorsulon)
POM-VPSBoehringer Ingelheim Vetmedica GmbH
Ivomec Super Injection for Cattle (Ivermectin and Clorsulon)
POM-VPSBoehringer Ingelheim Vetmedica GmbH
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