Stronghold Plus 15 mg/2.5 mg Spot-on Solution for Cats ≤2.5 kg

It is recommended, in accordance with good veterinary practice, that all animals 6
months of age or more, living in countries where a vector exists should be tested for
existing adult heartworm infections before beginning preventive use with the
veterinary medicinal product.
This veterinary medicinal product is not effective against adult D. immitis. The
administration to animals with adult heartworm infection did not pose safety
concerns.
Whilst not routinely indicated, the potential benefits of performing periodic testing for
heartworm infection in individual cases should be considered by the responsible
veterinarian.
Ticks need to start feeding on the host to become exposed to sarolaner; therefore,
the transmission of infectious tick-borne diseases cannot be excluded.

Amended pages: December 2025
AN: 03498/2024Page 3 of 9
The efficacy of the veterinary medicinal product has not been established in cats with
severe clinical signs of . Use of the veterinary medicinal product in such cases
should be based on the benefit-risk assessment of the responsible veterinarian.

Special precautions for use in animals
Use of this veterinary medicinal product is indicated in cats aged at least 8 weeks old
and weighing at least 1.25 kg bodyweight.
This veterinary medicinal product is to be applied to the skin surface only. Do not
administer orally or parenterally.
Do not apply when the animal’s hair coat is wet.
For ear mite treatment, do not apply directly to the ear canal.
It is important to apply the dose as indicated to prevent the animal from licking and
ingesting the product. If significant ingestion occurs, transient gastrointestinal effects
such as hypersalivation, emesis, soft faeces or reduced food consumption may be
observed and should normally resolve without treatment.
Keep treated animals away from fires and other sources of ignition for at least 30
minutes or until the hair coat is dry.
Special precautions to be taken by the person administering the veterinary medicinal
product to animals
The veterinary medicinal product is harmful after ingestion. Keep the veterinary
medicinal product in the original packaging until use, in order to prevent children from
getting direct access to the veterinary medicinal product. Used pipettes should be
disposed of immediately. In case of accidental ingestion, seek medical advice
immediately and show the package leaflet or the label to the physician.
The veterinary medicinal product may cause eye irritation. Avoid eye contact
including hand-to-eye-contact. Avoid direct contact with treated animals until the
application area is dry. Wash hands after use and wash off any veterinary medicinal
product in contact with the skin immediately with soap and water. In case of
accidental eye exposure, flush the eyes immediately with water, seek medical advice
immediately and show the package leaflet or the label to the physician.
Children are not allowed to play with treated cats for 4 hours after treatment. It is
recommended to treat animals in the evening. On the day of treatment, treated
animals should not be permitted to sleep in the same bed as their owner, especially
children.
People with sensitive skin or known allergy to veterinary medicinal products of this
type should handle the veterinary medicinal product with caution.
The veterinary medicinal product is highly flammable. Keep away from heat, sparks,
open flame or other sources of ignition.

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AN: 03498/2024Page 4 of 9
Special precautions for the protection of the environment
Not applicable.
Other precautions
Not applicable.