Rispoval IBR-Marker Inactivated Suspension for Injection for Cattle

The vaccination scheme consists of basic immunisation and booster vaccinations.
Basic immunisation:
Cattle at 3 months of age or older at first vaccination
Two doses, each of 2 ml, 3-5 weeks apart.
Booster vaccinations:
Booster vaccinations of cattle having been administered the primary vaccination
scheme using Rispoval IBR-Marker Inactivatum:
One dose of 2 ml at 6 month intervals.
Booster Vaccinations of cattle having been administered the primary vaccination
scheme using Rispoval IBR-Marker Vivum*:
Cattle having been administered the primary vaccination scheme using Rispoval
IBR-Marker Vivum* (according to the product information for this veterinary medicinal
product) may be given booster vaccinations with Rispoval IBR-Marker Inactivatum.
These animals should be given a single dose booster vaccination with Rispoval IBR-
Marker Inactivatum 6 months after their initial vaccination course with Rispoval IBR-
Marker Vivum*. Thereafter, single dose booster vaccinations with Rispoval IBR-
Marker Inactivatum should be administered every 12 months.
If calves under the age of 3 months should be vaccinated the development of
immunity may be impaired by maternal antibodies. These calves should be
revaccinated when they are over 3 months of age.
It is recommended to vaccinate all cattle of a herd.
For female cattle for protection against abortion:
To prevent abortions associated with BoHV-1 female cattle require a primary course
of two subcutaneous doses of vaccine 3-5 weeks apart, or alternatively a primary
course of a single intramuscular dose of Rispoval IBR-Marker Vivum* followed 6
months later by a single dose booster using Rispoval IBR-Marker Inactivatum. In
order to cover the main abortion risk period, it is recommended that the second dose
of the primary course of two subcutaneous doses or the single dose booster using
Rispoval IBR-Marker Inactivatum is administered no later than by the start of the
second trimester of each pregnancy.
Method of administration:
Shake the vaccine well before use. Use only sterile needles and syringes for
administration. Avoid the introduction of contamination during use. The liquid
suspension is injected aseptically via the subcutaneous route.
Vaccination schemes summary:
From 2 weeks to 3 months of age
Rispoval IBR-Marker vaccine usedPrimary VaccinationRevaccination IntervalsFirst dose
(vaccine, route of
administration)
Second dose
(vaccine, route
of
administration)
Interval to next
booster
vaccination
(vaccine, route of
administration)
All subsequent
booster
vaccinations
(vaccine, route of
administration)
2 weeks (Vivum*,
intranasal)
3 months
(Vivum*,
intramuscular)
6 months (Vivum*,
intramuscular)
6 months (Vivum*,
intramuscular)
2 weeks (Vivum*,
intranasal)
3 months
(Vivum*,
intramuscular)
6 months
(Inactivatum,
subcutaneous)
12 months
(Inactivatum,
subcutaneous)
From 3 months of ageRispoval IBR-Marker vaccine usedRevaccination IntervalsPrimary Vaccination
(number of doses, route of
administration)
Interval to first
booster vaccination
(vaccine, route of
administration)
All subsequent
booster vaccinations
(vaccine, route of
administration)
Vivum* (one dose, intramuscular
or intranasal)
6 months (Vivum*,
intramuscular)
6 months (Vivum*,
intramuscular)
Vivum* (one dose,
intramuscular)
6 months
(Inactivatum,
subcutaneous)
12 months
(Inactivatum,
subcutaneous)
Inactivatum (two doses,
subcutaneous, with 3-5 week
interval)
6 months
(Inactivatum,
subcutaneous)
6 months (Inactivatum,
subcutaneous)
For female cattle for protection against abortion
Rispoval IBR-Marker vaccine usedPrimary Vaccination
(number of doses, route
of administration)
recommended to be
applied no later than by
the start of second
trimester of pregnancy
Revaccination
Vivum* (two doses,
intramuscular, with 3-5 weeks
interval)
Vivum* (one dose, intramuscular)
followed by Inactivatum (one
dose, subcutaneous), with 6
months interval
Inactivatum (two doses,
subcutaneous, with 3-5 week
interval)
Inactivatum (one dose, subcutaneous)
recommended to be applied no later than by
the start of the second trimester of each
pregnancy
For vaccination in known high BoHV-1 infection pressure
Rispoval IBR-Marker vaccine usedRevaccination IntervalsPrimary Vaccination
(number of doses,
route of
administration)
Interval to first
booster
vaccination
(vaccine, route of
administration)
All subsequent
booster
vaccinations
(vaccine, route of
administration)
Vivum* (one dose,
intranasal), followed by
Vivum* (one dose,
6 months (Vivum*,
intramuscular, OR
Inactivatum,
subcutaneous)
6 months (Vivum*,
intramuscular) OR 12
months (Inactivatum,
subcutaneous)
intramuscular) with 3-5
weeks interval
* Where this veterinary medicinal product is authorised.