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POM-V Prescription Required

Rispoval 4

Active ingredients: Bovine parainfluenza virus 3, Bovine respiratory syncytial virus, Bovine viral diarrhoea virus, Infectious bovine rhinotraceitis virus

Form

Injection

Species

Cattle

Manufacturer

Zoetis Belgium S.A.

VMD MA No.

60021/3018

What it's used for

Duration of immunity: at least 6 months.

Full indications, dosage and side effects ↓
View official SPC (PDF)

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Prescription required

Your vet must provide a written prescription on request. You can then purchase from any licensed online retailer.

Clinical information

Rispoval 4 — SPC Details

Source: VMD Summary of Product Characteristics (SPC). Last updated 27 Mar 2026.

Duration of immunity: at least 6 months.
When the lyophilised plug and liquid fraction are filled in equally sized vials:
•
When the lyophilised fraction is filled in a smaller vial size than the liquid fraction, the
reconstitution of the vaccine is carried out in 2 steps:
•
vial.
•
freeze-dried vial and mix with the liquid fraction in the liquid fraction vial.
Shake well before use.
Vaccination programme:
For cattle over 3 months of age:
Two doses of 5ml of reconstituted vaccine should be given three to four weeks apart
to cattle over the age of 3 months, via the intramuscular route.
Ideally, calves should be vaccinated at least 2 weeks before transport, mixing of
animals of different origins, housing, or any other event which may cause the animals
to be stressed or exposed to new infections. Calves are usually most susceptible
during early autumn. The vaccine will protect animals against BRSV, PI3, IBR and
BVD for at least 6 months, which will cover the period of risk from respiratory
infections.
Should cattle be at risk from these respiratory diseases at a subsequent time, the
same vaccination scheme is recommended at least 14 days prior to the period of
expected disease challenge.
For cattle over 3 weeks of age:
For cattle from 3 weeks of age, vaccination leads to seroconversion of seronegative
calves vaccinated at 3 and 6 weeks of age. The influence of maternally derived
antibodies has not been studied in detail and it is therefore recommended that calves
vaccinated before 12 weeks of age are re-vaccinated at 12 weeks of age.
None.
Cattle:
Very rare
(<1 animal / 10,000 animals
treated, including isolated
reports):
Injection site reaction
1
Mild, transient. Up to 0,5cm and completely resolved within 15days.
Reporting adverse events is important. It allows continuous safety monitoring of a
veterinary medicinal product. Reports should be sent, preferably via a veterinarian, to
either the marketing authorisation holder or the national competent authority via the
national reporting system. See the package leaflet for respective contact details.
Vaccinate healthy animals only.

Special precautions for safe use in the target species:
Not applicable.
Special precautions to be taken by the person administering the veterinary medicinal
product to animals:
Not applicable.
Special precautions for the protection of the environment:
Not applicable.
Safety and efficacy data are available which demonstrate that this vaccine can be
administered on the same day but not mixed with Rispoval Pasteurella.
No information is available on the safety and efficacy of this vaccine when used with
any other veterinary medicinal product except the product mentioned above. A
decision to use this vaccine before or after any other veterinary medicinal product
therefore needs to be made on a case-by-case basis.
Store and transport refrigerated (2 C – 8 C).
Do not freeze.
Protect from light.
Zero days.

This information is sourced from the official Summary of Product Characteristics (SPC) published by the Veterinary Medicines Directorate (VMD). It is provided for informational purposes only and does not replace professional veterinary advice. Always consult your vet before administering any medication.

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