Pulmovet 250 mg/ml Solution for Use in Drinking Water/Milk for Cattle, Pigs, Chickens and Turkeys

chickens, turkeys) or milk replacer (calves) before administration.
Calves: 12.5 mg tilmicosin/kg body weight (i.e.1 ml of veterinary medicinal product per 20
kg BW), twice daily, for 3-5 consecutive days.
Pigs: 15-20 mg tilmicosin/kg body weight/day (i.e. 6-8 ml of veterinary medicinal product
per 100 kg of BW per day), for 5 consecutive days, which may be achieved by the
inclusion of 200 mg of tilmicosin per litre (80 ml of veterinary medicinal product per 100
litres).
Chickens: 15-20 mg tilmicosin/kg body weight/day (i.e. 6-8 ml of veterinary medicinal
product per 100 kg of BW per day), for 3 consecutive days, which may be achieved by the
inclusion of 75 mg of tilmicosin per litre (30 ml of veterinary medicinal product per 100
litres).
Turkeys: 10-27 mg tilmicosin/kg body weight/day (i.e. 4-11 ml of veterinary medicinal
product per 100 kg of BW per day), for 3 consecutive days, which may be achieved by the
inclusion of 75 mg of tilmicosin per litre (30 ml of veterinary medicinal product per 100
litres).
Based on the recommended dose and the number and weight of animals to be treated, the
exact daily concentration of the veterinary medicinal product should be calculated
according to the following formula:
ml veterinary medicinal product per litre of drinking water = [ml veterinary medicinal
product per kg body weight per day x average body weight (kg) of animals to be treated] /
average daily water intake (l/animal).
One 960 ml bottle of veterinary medicinal product is sufficient to medicate 1200 litres of
drinking water for pigs or 3200 litres of drinking water for chickens or turkeys. One 5040 ml
can is sufficient to medicate 6300 litres of drinking water for pigs or 16800 litres of drinking
water for chickens or turkeys.
One 960 ml bottle and 5040 ml can of veterinary medicinal product are sufficient to
medicate in milk replacer respectively 48 to 80 and 252 to 420 veal calves each of 40 kg
body weight depending on the duration of treatment.
To ensure a correct dosage, body weight should be determined as accurately as possible.
The required dose should be measured using suitably calibrated measuring equipment.
Only sufficient medicated drinking water should be prepared to cover the daily
requirements.
The medicated water should be the only source of drinking water for the animals for the
entire duration of the treatment period.
Water intake should be monitored at frequent intervals during medication.
After the end of the medication period, the water supply system should be cleaned
appropriately to avoid intake of sub-therapeutic amounts of the active substance.
Medicated drinking water should be prepared fresh every 24 hours. Medicated milk
replacer should be prepared fresh every 6 hours.
The veterinary medicinal product should be diluted with water or milk replacer prior to its
use and the concentration of the prediluted solution should not exceed 200 ml of veterinary
medicinal product/litre (i.e. 1 in 5). The lowest concentrations of the veterinary medicinal
product at which stability can be assured are 0.3 ml veterinary medicinal product/litre
drinking water and 0.7 ml veterinary medicinal product/litre milk replacer.
The intake of medicated water/milk replacer depends on the clinical condition of the
animals. In order to obtain the correct dosage, the concentration of tilmicosin may need to
be adjusted accordingly.