POM-V Prescription Required

Pulmotil AC 250 mg/ml Concentrate for Oral Solution for Use in Drinking Water or Milk Replacer

Active ingredient: Tilmicosin

Form

Liquid

Species

Cattle Chickens Pigs Turkeys

Manufacturer

Elanco Europe Ltd

VMD MA No.

00879/5085

What it's used for

Pigs: For the treatment and metaphylaxis of respiratory disease in pig herds, associated with Mycoplasma hyopneumoniae, Pasteurella multocida, Actinobacill...

Full indications, dosage and side effects ↓

View official SPC (PDF)

The prescription itself has a price. See what practices near you charge for a consultation and the written prescription fee.

Paying less for Tilmicosin

1

Ask your vet for a written prescription

They must provide one on request. Under the CMA Order the fee is capped at £21 from 2027.
2

Fill it at a registered online retailer

The CMA found online pharmacies 50–60% cheaper than practice dispensing on common medicines — typically £200–£300 a year.

Your prescription rights → VMD register of retailers →

Prescription required

Your vet must provide a written prescription on request. You can then purchase from any licensed online retailer.

Clinical information

Pulmotil AC 250 mg/ml Concentrate for Oral Solution for Use in Drinking Water or Milk Replacer — SPC Details

Source: VMD Summary of Product Characteristics (SPC). Last updated 26 Mar 2026.

Pigs: For the treatment and metaphylaxis of respiratory disease in pig herds,
associated with Mycoplasma hyopneumoniae, Pasteurella multocida,
Actinobacillus pleuropneumoniae and other organisms susceptible to tilmicosin.
Chickens: For the treatment and metaphylaxis of respiratory disease in chicken
flocks, associated with Mycoplasma gallisepticum M. synoviae.
Turkeys: For the treatment and metaphylaxis of respiratory disease in turkey
flocks, associated with Mycoplasma gallisepticum M. synoviae.
Calves: For the treatment and metaphylaxis of bovine respiratory disease,
associated with Mannheimia haemolytica, Pasteurella multocida, Mycoplasma
bovis, M. dispar and other organisms susceptible to tilmicosin.
The presence of the disease in the group/flock must be established before the
product is used.

Revised: September 2020
AN: 00822/2020

For oral use only. Do not inject.
Pigs: To be included in the drinking water to provide a daily dose of 15-20 mg/kg
bodyweight for 5 days, which may be achieved by the inclusion of 200 mg
tilmicosin per litre (80 ml Pulmotil AC per 100 litres).
Chickens and Turkeys (except hens producing eggs for human consumption): To
be included in the drinking water at a daily dose of 15-20 mg/kg bodyweight in
chickens and 10-27 mg/kg bodyweight in turkeys for 3 days, which may achieved
by the inclusion of 75 mg tilmicosin per litre (30 ml Pulmotil AC per 100 litres).
Calves: To be included in milk replacer only, at a dose of 12.5 mg/kg bodyweight
and given twice daily for 3-5 consecutive days, which may be achieved by the
inclusion of 1 ml of product every 20 kg bodyweight.
One 240 ml bottle of Pulmotil AC is sufficient to medicate 300 litres of drinking
water for pigs or 800 litres of drinking water for chickens or turkeys. One 960 ml

Revised: September 2020
AN: 00822/2020
bottle is sufficient to medicate 1200 litres of drinking water for pigs or 3200 litres
of drinking water for chickens or turkeys.
One 240 ml bottle and 960 ml bottle of Pulmotil AC are sufficient to medicate in
milk replacer respectively 12 to 20 and 48 to 80 veal calves each of 40 kg
bodyweight depending on the duration of treatment.
The uptake of medicated water/milk replacer depends on the clinical condition of
the animals. In order to obtain the correct dosage, the concentration of Pulmotil
AC should be adjusted accordingly.
To ensure a correct dosage, bodyweight should be determined as accurately as
possible to avoid under-dosing.
The required dose should be measured using suitably calibrated measuring
equipment.
Only sufficient medicated drinking water should be prepared to cover the daily
requirements.

Do not allow horses and other equines access to drinking water containing
tilmicosin.
Do not use in case of hypersensitivity to tilmicosin or to any of the excipients.

In very rare cases (less than 1 animal in 10,000 animals treated , including
isolated reports), a decrease in water intake has been observed.

Important: Must be diluted before administration to animals.
Pigs, chickens and turkeys: Water consumption should be monitored in order to
guarantee adequate dosing. In case water consumption does not match
quantities for which recommended concentrations were calculated, the
concentration of Pulmotil AC has to be adapted in a way that the recommended
dosage will be taken up by the animals or different medication should be
considered.

i. Special precautions for use in animals
For oral use only. Contains disodium edetate; do not inject
Severely ill individuals tend to drink less and may need simultaneous
treatment, preferably by parenteral medication.
Inappropriate use of the product may increase the prevalence of bacteria
resistant to tilmicosin and may decrease the effectiveness of treatment with
tilmicosin-related substances.
The use of the product should be based on susceptibility testing of the
bacteria isolated from the animal. If this is not possible, therapy should be
based on local (regional, farm level) epidemiological information about
susceptibility of the target bacteria.
Medicated drinking water or milk replacer should be prepared fresh every 24
hours.
Official, national and regional antimicrobial policies should be taken into
account when the product is used.
ii. Special precautions to be taken by the person administering the veterinary
medicinal product to animals
- Tilmicosin may induce irritation. Macrolides, such as tilmicosin, may also
cause hypersensitivity (allergy) following injection, inhalation, ingestion or
contact with skin or eye. Hypersensitivity to tilmicosin may lead to cross
reactions to other macrolides and vice versa. Allergic reactions to these
substances may occasionally be serious and therefore direct contact
should be avoided.

Revised: September 2020
AN: 00822/2020
- To avoid exposure during preparation of the medicated drinking water,
wear overalls, safety glasses, and impervious gloves. Do not eat, drink or
smoke when handling this product. Wash hands after use.
- In the case of accidental ingestion, wash out mouth immediately with water
and seek medical advice. In the event of accidental skin contact, wash
thoroughly with soap and water. In case of accidental eye contact, flush
the eyes with plenty of clean, running water.
- Do not handle the product if you are allergic to ingredients in the product.
- If you develop symptoms following exposure, such as skin rash, you
should seek medical advice and show the physician this warning. Swelling
of the face, lips and eyes or difficulty in breathing are more serious
symptoms and require urgent medical attention.

None known.

Pigs: meat and offal: 14 days
Chickens: meat and offal: 12 days
Turkeys: meat and offal: 19 days
Calves: meat and offal: 42 days

Revised: September 2020
AN: 00822/2020
Not authorised for use in animals producing milk for human consumption.
Not authorised for use in birds producing eggs for human consumption.
Do not use within 2 weeks of the start of the laying period.
5.

This information is sourced from the official Summary of Product Characteristics (SPC) published by the Veterinary Medicines Directorate (VMD). It is provided for informational purposes only and does not replace professional veterinary advice. Always consult your vet before administering any medication.