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Powdox Doxycycline 500 mg/g Powder for Use in Drinking Water for Pigs, Chickens and Turkeys

Active ingredient: Doxycycline

Form

Powder

Species

Chickens Pigs Turkeys

Manufacturer

Vetpharma Animal Health, S.L

VMD MA No.

32509/4009

What it's used for

Pigs: treatment of clinical respiratory infections caused by hyopneumoniae and Pasteurella multocida strains susceptible to doxycycline. Chickens and turke...

Full indications, dosage and side effects ↓

View official SPC (PDF)

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Paying less for Doxycycline

1

Ask your vet for a written prescription

They must provide one on request. Under the CMA Order the fee is capped at £21 from 2027.
2

Fill it at a registered online retailer

The CMA found online pharmacies 50–60% cheaper than practice dispensing on common medicines — typically £200–£300 a year.

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Prescription required

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Clinical information

Powdox Doxycycline 500 mg/g Powder for Use in Drinking Water for Pigs, Chickens and Turkeys — SPC Details

Source: VMD Summary of Product Characteristics (SPC). Last updated 26 Mar 2026.

Pigs: treatment of clinical respiratory infections caused by
hyopneumoniae and Pasteurella multocida strains susceptible to doxycycline.
Chickens and turkeys: treatment of clinical respiratory infections associated with
Mycoplasma gallisepticum susceptible to doxycycline.

In drinking water use.
In pigs and chickens, 23.1 mg doxycycline hyclate per kg of body weight daily
(equivalent to 40.0 mg product per kg of body weight), administered in the
drinking water for 5 consecutive days.
In turkeys, 28.8 mg doxycycline hyclate per kg of body weight daily (equivalent
to 50.0 mg product per kg of body weight), administered in the drinking water for
5 consecutive days.
Based on the recommended dose, and the number and weight of the animals to
be treated, the exact daily amount of the veterinary product should be
calculated according to the following formula:
mg product / kg body weight /
day
x Mean body weight (kg) of
animals to be treated
Mean daily water consumption (l) per animal = .... mg
product
per l
drinking
water

Revised: July 2024
AN: 00573/2024 & 00999/2024
To ensure a correct dosage body weight should be determined as accurately as
possible. The uptake of medicated water is dependent on the clinical condition
of the animals. In order to obtain the correct dosage, the concentration in
drinking water may have to be adjusted.
The use of suitably calibrated weighing equipment is recommended if part
packs are used. The daily amount is to be added to the drinking water such that
all medication will be consumed in 24 hours. It is recommended to prepare a
concentrated pre-solution and to dilute this further to therapeutic concentrations
if required. Alternatively, the concentrated solution can be used in a proportional
water medicator.
Medicated water should be refreshed every 24 hours. The medicated water
should be the only source of drinking water, throughout the treatment period.
The medicated water must not be prepared or stored in a metal container.
The maximum solubility of the product in water is 72 g/L. Solubility of the
product is pH dependent and it will precipitate if it is mixed in an alkaline
solution.

Do not use in cases of hypersensitivity to the active substance or to any
excipient.
Do not use in animals with hepatic dysfunction.

On rare occasions allergic reactions and photosensitivity may occur. If
suspected adverse re-actions occur, treatment should be discontinued.

Revised: July 2024
AN: 00573/2024 & 00999/2024
The frequency of adverse reactions is defined using the following convention:
- very common (more than 1 in 10 animals treated displaying adverse
reaction(s))
- common (more than 1 but less than 10 animals in 100 animals treated)
- uncommon (more than 1 but less than 10 animals in 1,000 animals treated)
- rare (more than 1 but less than 10 animals in 10,000 animals treated)
- very rare (less than 1 animal in 10,000 animals treated, including isolated
reports).

The uptake of medication by animals can be altered as a consequence of
illness. In case of insufficient uptake of drinking water, animals should be
treated parenterally.
Under-dosing and/or treating for an insufficient length of time are considered to
promote the development of resistance in bacteria and should be avoided.

Revised: July 2024
AN: 00573/2024 & 00999/2024

Special precautions for use in animals
Inappropriate use of the product may increase the prevalence of bacteria
resistant to tetracycline due to the potential for cross resistance.
Use of the product should be based on susceptibility testing of the bacteria
isolated from the animal. If this is not possible, therapy should be based on local
(regional, farm level) epidemiological information about susceptibility of the
target bacteria.
The safety of the product has not been established in piglets before weaning.
Avoid administration in oxidised drinking equipment.
Do not use when tetracycline resistance has been detected in the herd/flock
due to the potential for cross resistance.
Due to the likely variability (time, geographical) in the occurrence of resistance
of bacteria for doxycycline, bacteriological sampling and susceptibility testing
are highly recommended.
A high resistance rate of , isolated from chickens, against tetracyclines
has been documented. Therefore the product should be used for the treatment
of infections caused by only after susceptibility testing has been carried
out.
As eradication of the target pathogens may not be achieved, medication should
therefore be combined with good management practices, e.g. good hygiene,
proper ventilation, no overstocking.
Special precautions to be taken by the person administering the veterinary
medicinal product to animals
During preparation and administration direct contact of the product with the skin,
eyes and mucous membranes and inhalation of dust particles should be
avoided.People with known hypersensitivity to tetracyclines should avoid
contact with the veterinary medicinal product.
Personal protective equipment consisting of protective gloves (e.g. rubber or
latex), goggles and an appropriate dust mask (either a disposable half-mask
respirator conforming to European Standard EN 149 or a non-disposable
respirator to European Standard EN 140 with a filter to EN 143) should be worn
when handling the veterinary medicinal product. Wash exposed skin after
preparation. In case of accidental projection into the eyes, rinse abundantly with
water. Do not smoke, eat or drink when handling the product.
In case of accidental ingestion, seek medical advice immediately and show the
package leaflet or the label to the physician. Inflammation of the face, lips or
eyes or respiratory difficulties are the most serious signs which require urgent
medical attention.

Do not administer concurrently with feed overloaded with polyvalent cations
such as Ca
2+
, Mg
2+
, Zn
2+
and Fe
3+
because the formation of doxycycline
complexes with these cations is possible.
administration of other products containing polyvalent cations should be 1-2
hours because they limit the absorption of tetracycline.
Do not administer together with antacids, kaolin or iron preparations.
Do not administer in conjunction with bactericidal antibiotics such as beta-
lactams as tetracyclines are bacteriostatic antimicrobials
Doxycycline increases the action of anticoagulants.

Do not store above 25ºC.

Pigs:
Meat and offal:4 days
Chickens:
Meat and offal:5 days
Turkeys:
Meat and offal:12 days
Not for use in birds producing or intended to produce eggs for human
consumption.
5.

This information is sourced from the official Summary of Product Characteristics (SPC) published by the Veterinary Medicines Directorate (VMD). It is provided for informational purposes only and does not replace professional veterinary advice. Always consult your vet before administering any medication.