POM-V Prescription Required

Powdox 100 mg/ml Oral Solution for Use in Drinking Water for Chickens and Pigs

Active ingredient: Doxycycline

Form

Liquid

Species

Chickens Pigs

Manufacturer

Vetpharma Animal Health, S.L

VMD MA No.

32509/4006

What it's used for

PIGS Prevention of clinical respiratory disease due to and Mycoplasma hyopneumoniae The presence of the disease in the herd should be established before tr...

Full indications, dosage and side effects ↓

View official SPC (PDF)

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Paying less for Doxycycline

1

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2

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Prescription required

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Clinical information

Powdox 100 mg/ml Oral Solution for Use in Drinking Water for Chickens and Pigs — SPC Details

Source: VMD Summary of Product Characteristics (SPC). Last updated 27 Mar 2026.

PIGS
Prevention of clinical respiratory disease due to
and Mycoplasma hyopneumoniae
The presence of the disease in the herd should be established before
treatment.

weight / day, corresponding to 0.1 -0.2 ml of POWDOX the veterinary
product per kg body weight, for 3-5 consecutive days.
- PIGS: 11.5 mg doxycycline hyclate/ kg body weight / day,
corresponding to 0.1 ml of the veterinary product per kg body weight,
for 5 consecutive days.
AN: 00668/2024 & 00982/2024
Based on the recommended dose, and the number and weight of the
animals to be treated, the exact daily amount of the veterinary product
should be calculated according to the following formula:
X ml veterinary
product/ kg
b.w./dayx
Mean body
weight (kg) of
animals to be
treated
=
X ml veterinary
product per l
drinking water
Mean daily water consumption (l) per animal
To ensure a correct dosage body weight should be determined as
accurately as possible to avoid underdosing. The uptake of medicated
water is dependant on the clinical condition of the animals. In order to
obtain the correct dosage, the concentration in drinking water may have
to be adjusted.
The use of suitably calibrated weighing equipment is recommended if
part packs are used. The daily amount is to be added to the drinking
water such that all medication will be consumed in 24 hours. Medicated
drinking water should be freshly prepared every 24 hours. It is
recommended to prepare a concentrated pre-solution – approximately
100 grams product per litre drinking water – and to dilute this further to
therapeutic concentrations if required. Alternatively, the concentrated
solution can be used in a proportional water medicator.
Medicated water should be the only drinking source.
The remaining medicated water should be disposed of in accordance
with local requirements.
If no improvement in clinical signs is seen within the treatment duration,
the diagnosis should be reviewed and treatment changed.

Do not use in case of hypersensitivity to tetracyclines.
Do not use in cases of resistance to tetracyclines.
AN: 00668/2024 & 00982/2024
Do not use in animals with hepatic dysfunction.

Allergic and photosensitivity reactions can occur. Intestinal flora may be
affected if treatment is very prolonged, and this may result in digestive
disturbance.
If suspected adverse reactions occur, treatment should be discontinued.

Sick animals may have a reduced appetite and altered drinking patterns
and should, if necessary, be medicated parenterally.
In cases of altered food or drinking water uptake, the concentrations
should be adjusted in such a way that the recommended dosage is
achieved.
Do not administer to laying hens.

Special precautions for use in animals
Prolonged or repeated use of this veterinary medicinal product is
discouraged. Attention should be paid to avoidance of stressful
conditions and improvement of management practices and hygiene
standards.
Avoid administration in oxidised drinking equipment.
Use of the product should be based on susceptibility testing of the
bacteria isolated from the animal. If this is not possible, therapy should
be based on local (regional and farm level) epidemiological information
about susceptibility of the target bacteria, taking into account official
national antimicrobial policies. Inappropriate use of the product may
increase the prevalence of bacteria resistant to doxycycline and may
decrease the effectiveness of treatment with tetracyclines, due to the
potential for cross-resistance.
Due to variability (time, geographical) in susceptibility of bacteria for
doxycycline, bacteriological sampling and susceptibility testing of micro-
organisms from diseased birds on farm are highly recommended.
A high resistance rate of
tetracyclines has been documented. Therefore the product should be
used for the treatment of infections caused by only after
susceptibility testing has been carried out.
As eradication of the target pathogens may not be achieved, medication
should therefore be combined with good management practices, e.g.
good hygiene, proper ventilation, no overstocking.
Special precautions to be taken by the person administering the
veterinary medicinal product to animals
Tetracyclines may – in very rare cases – induce photosensitivity and
allergic reactions.
Do not handle the product if you are hypersensitive to tetracyclines.
Wear gloves, work overall and approved safety glasses.
AN: 00668/2024 & 00982/2024
This product is acid and likely to be irritant. Avoid contact with skin and
eyes. In case of contact with skin, rinse immediately with plenty of water.
In case of contact with eyes, rinse immediately with copious amounts of
water and seek medical advice.
Do not smoke, eat or drink while handling this product.
The product can be harmful by skin contact and inhalation and may
cause eye irritation.
In case of accidental ingestion seek medical advise and show the label to
the doctor.
If any symptom should appear, such as a cutaneous eruption, seek
prompt medical advice. Swelling of the face, lips or eyes or respiratory
difficulties are the most serious signs which require urgent medical
attention.

interaction
Doxycycline absorption may be reduced by the presence of high
quantities of calcium, iron, magnesium or aluminium in the diet. Do not
administer together with antacids, kaolin and iron preparations.
Do not administer together with bactericidal antibiotics.
The solubility of the product is pH dependent and will precipitate if mixed
in alkaline solution
Do not administer with milk replacers

Do not store above 25ºC.
Protect from light.
AN: 00668/2024 & 00982/2024

Special precautions for use in animals
Prolonged or repeated use of this veterinary medicinal product is
discouraged. Attention should be paid to avoidance of stressful
conditions and improvement of management practices and hygiene
standards.
Avoid administration in oxidised drinking equipment.
Use of the product should be based on susceptibility testing of the
bacteria isolated from the animal. If this is not possible, therapy should
be based on local (regional and farm level) epidemiological information
about susceptibility of the target bacteria, taking into account official
national antimicrobial policies. Inappropriate use of the product may
increase the prevalence of bacteria resistant to doxycycline and may
decrease the effectiveness of treatment with tetracyclines, due to the
potential for cross-resistance.
Due to variability (time, geographical) in susceptibility of bacteria for
doxycycline, bacteriological sampling and susceptibility testing of micro-
organisms from diseased birds on farm are highly recommended.
A high resistance rate of
tetracyclines has been documented. Therefore the product should be
used for the treatment of infections caused by only after
susceptibility testing has been carried out.
As eradication of the target pathogens may not be achieved, medication
should therefore be combined with good management practices, e.g.
good hygiene, proper ventilation, no overstocking.
Special precautions to be taken by the person administering the
veterinary medicinal product to animals
Tetracyclines may – in very rare cases – induce photosensitivity and
allergic reactions.
Do not handle the product if you are hypersensitive to tetracyclines.
Wear gloves, work overall and approved safety glasses.
AN: 00668/2024 & 00982/2024
This product is acid and likely to be irritant. Avoid contact with skin and
eyes. In case of contact with skin, rinse immediately with plenty of water.
In case of contact with eyes, rinse immediately with copious amounts of
water and seek medical advice.
Do not smoke, eat or drink while handling this product.
The product can be harmful by skin contact and inhalation and may
cause eye irritation.
In case of accidental ingestion seek medical advise and show the label to
the doctor.
If any symptom should appear, such as a cutaneous eruption, seek
prompt medical advice. Swelling of the face, lips or eyes or respiratory
difficulties are the most serious signs which require urgent medical
attention.
4.

This information is sourced from the official Summary of Product Characteristics (SPC) published by the Veterinary Medicines Directorate (VMD). It is provided for informational purposes only and does not replace professional veterinary advice. Always consult your vet before administering any medication.