POM-V Prescription Required

Parofor Crypto 140 000 IU/ml Oral Solution for Pre-Ruminant Cattle

Active ingredient: Paromomycin

Form

Liquid

Species

Cattle

Manufacturer

Huvepharma N.V.

VMD MA No.

30282/3014

What it's used for

Calves should only receive the veterinary medicinal product upon confirmation of cryptosporidial oocysts in their faeces and before the onset of diarrhoea....

Full indications, dosage and side effects ↓

View official SPC (PDF)

The prescription itself has a price. See what practices near you charge for a consultation and the written prescription fee.

Paying less for Paromomycin

1

Ask your vet for a written prescription

They must provide one on request. Under the CMA Order the fee is capped at £21 from 2027.
2

Fill it at a registered online retailer

The CMA found online pharmacies 50–60% cheaper than practice dispensing on common medicines — typically £200–£300 a year.

Your prescription rights → VMD register of retailers →

Prescription required

Your vet must provide a written prescription on request. You can then purchase from any licensed online retailer.

Clinical information

Parofor Crypto 140 000 IU/ml Oral Solution for Pre-Ruminant Cattle — SPC Details

Source: VMD Summary of Product Characteristics (SPC). Last updated 27 Mar 2026.

Calves should only receive the veterinary medicinal product upon confirmation of
cryptosporidial oocysts in their faeces and before the onset of diarrhoea.
Paromomycin reduces faecal oocyst shedding.

Dose rate: 35 000 IU of paromomycin/kg BW/day for 7 consecutive days, i.e. 2.5 ml
of veterinary medicinal product / 10 kg BW/day for 7 consecutive days.
To ensure a correct dosage, the use of either a syringe or an appropriate device for
oral administration is necessary and the veterinary medicinal product should be
administered directly in the mouth of the animal.
To ensure a correct dosage, bodyweight should be determined as accurately as possible.

Do not use in cases of hypersensitivity to the active substance, to other
aminoglycosides or to any of the excipients.
Do not use in cases with impaired function of the kidneys or liver.
Do not use in ruminating animals.

Cattle:
Undetermined frequency
(cannot be estimated from
available data)
Nephropathy (nephrotoxicity)
Internal ear disorder (ototoxicity)
1
can be caused by aminoglycoside antibiotics such as paromomycin
Reporting adverse events is important. It allows continuous safety monitoring of a
veterinary medicinal product. Reports should be sent, preferably via a veterinarian, to
either the marketing authorisation holder or its local representative or the national
competent authority via the national reporting system. See the package leaflet for
respective contact details.

In field studies investigating the effect of the veterinary medicinal product on
diarrhoea associated with cryptosporidiosis, 23% to 32% of calves in treated groups
presented with diarrhoea, in comparison to 53% to 73% of calves in untreated
groups, during the 7-day treatment period.

Special precautions for safe use in the target species:
The use of the veterinary medicinal product should be combined with good
management practices e.g. good hygiene, proper ventilation and no overstocking.
Repeated use of the veterinary medicinal product on farms should be avoided by
improving management practices and through cleaning and disinfection.
Aminoglycosides are considered as critically important in human medicine. Use of the
veterinary medicinal product deviating from the instructions given in the SPC may
increase the prevalence of bacteria resistant to paromomycin and may decrease the
effectiveness of treatment with aminoglycosides due to the potential for cross-
resistance.
The safety of the veterinary medicinal product has not been investigated in animals
less than 3 days of age.
Special precautions to be taken by the person administering the veterinary medicinal
product to animals
This veterinary medicinal product contains paromomycin, which can cause allergic
reactions in some people.
People with known hypersensitivity to paromomycin or any other aminoglycoside
should avoid contact with the veterinary medicinal product.
Avoid contact with the skin and eyes.
In the event of accidental contact with the skin or eyes, rinse with plenty of clean
water.
If you develop symptoms following exposure, such as skin rash, you should seek
medical advice and show the package leaflet or the label to the physician. Swelling of
the face, lips and eyes or difficulty in breathing are more serious symptoms and
require urgent medical attention.
Personal protective equipment consisting of protective clothing and impervious
gloves should be worn when handling the veterinary medicinal product.
Do not eat, drink and smoke when handling the veterinary medicinal product.
Do not ingest. In case of accidental ingestion, seek medical advice immediately and
show the package leaflet or the label to the physician.
Wash hands after use.
Special precautions for the protection of the environment:
Not applicable.

General anaesthetics and muscle relaxing products increase the neuro-blocking
effect of aminoglycosides. This may cause paralysis and apnoea.
Do not use concurrently with strong diuretics and potentially oto- or nephrotoxic
substances.

Do not store above 25°C.

Due to accumulation of paromomycin in the liver and kidneys, any repeated course of
treatment during the withdrawal period must be avoided.
Meat and offal: 62 days

This information is sourced from the official Summary of Product Characteristics (SPC) published by the Veterinary Medicines Directorate (VMD). It is provided for informational purposes only and does not replace professional veterinary advice. Always consult your vet before administering any medication.