POM-V Prescription Required

Ocnil 400 mg/g Powder for Use in Drinking Water

Active ingredient: Lincomycin

Form

Powder

Species

Chickens Pigs

Manufacturer

Vetpharma Animal Health, S.L

VMD MA No.

32509/4021

What it's used for

Pigs Treatment and metaphylaxis of enzootic pneumonia caused by hyopneumoniae. The presence of the disease in the group must be established before the prod...

Full indications, dosage and side effects ↓

View official SPC (PDF)

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Paying less for Lincomycin

1

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They must provide one on request. Under the CMA Order the fee is capped at £21 from 2027.
2

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The CMA found online pharmacies 50–60% cheaper than practice dispensing on common medicines — typically £200–£300 a year.

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Clinical information

Ocnil 400 mg/g Powder for Use in Drinking Water — SPC Details

Source: VMD Summary of Product Characteristics (SPC). Last updated 26 Mar 2026.

Pigs
Treatment and metaphylaxis of enzootic pneumonia caused by
hyopneumoniae.
The presence of the disease in the group must be established before the product is
used.
Chickens:
perfringens.
The presence of the disease in the group must be established before the product is
used.

In drinking water use
Dosing guidance and recommended doses:
To ensure a correct dosage, body weight should be determined as accurately as
possible to avoid underdosing.

Revised January 2025
AN: 00963/2024 + 01298/2024Page 4 of 7
The intake of medicated water depends on the physiological and clinical condition of
the animals. In order to obtain the correct dosage, the concentration of the
lincomycin has to be adjusted accordingly.
The uptake of water should be monitored frequently.
The medicated water should be the only source of drinking water for the animals for
the entire duration of the treatment period.
After the end of the medication period, the water supply system should be cleaned
appropriately to avoid intake of sub-therapeutic amounts of the active substance.
Dosage:
Pigs:
Enzootic pneumonia: 10 mg lincomycin per kg of body weight (corresponding to 25
mg product per kg bodyweight) for 21 consecutive days.
Chickens:
Necrotic enteritis: 5 mg of lincomycin per kg body weight (corresponding to 12.5 mg
product per kg body weight) for 7 consecutive days.
The concentration to be used depends on the actual body weight and the water
consumption of the animals and can be calculated according to the following formula:
Dose (mg product per kg
body weight per day)X
mean body weight (kg)
of animals to be
treated
Average daily water intake (litre/animal)
= ___ mg product per
litre drinking water
The use of suitably calibrated weighing equipment is recommended if part packs are
used. The daily amount is to be added to the drinking water in such a way that all
medication will be consumed within 24 hours. Medicated drinking water should be
freshly prepared every 24 hours. No other source of drinking water should be
available.
The maximum solubility of finished product is 50 g/l in soft and hard water. For stock
solutions and when using a dosing pump, take care not to exceed the maximum
solubility which can be achieved under the given conditions. Adjust flow rate settings
of the dosing pump according to concentration of the stock solution and water intake
of the animals to be treated.

Do not use in cases of hypersensitivity to the active substance or to any of the
excipients.
Do not administer, and do not allow access to water containing lincomycin, to rabbits,
hamsters, guinea pigs, chinchillas, horses or ruminants as this could result in severe
gastrointestinal disturbances.

Revised January 2025
AN: 00963/2024 + 01298/2024Page 2 of 7
Do not use in cases of resistance to lincosamides.
Do not use in cases of hepatic dysfunction.

Pigs given lincomycin-medicated water may develop diarrhoea/soft stools and/or
mild swelling of the anus within the first 2 days after onset of treatment on rare
occasions. Some pigs may show reddening of the skin and mild irritable behaviour
on rare occasions. These conditions are usually self-correcting within 5-8 days
without discontinuing the lincomycin treatment. Allergic/hypersensitive reactions
occur on rare occasions.
The frequency of adverse reactions is defined using the following convention:

reactions)




reports).

Medicated drinking water uptake can be affected by the severity of the disease. In
case of insufficient uptake of water, pigs should be treated parenterally.
The susceptibility of to antimicrobial agents is difficult
to test owing to technical constraints. In addition, there is a lack of clinical
breakpoints for both and . Where possible, therapy
should be based on local (regional, farm level) epidemiological information
concerning the response of enzootic pneumonia/necrotic enteritis to treatment with
lincomycin

Special precautions for use in animals
Use of the veterinary medicinal product preferably should be based on identification
of the target pathogen and susceptibility testing
animal. However, also see text under section 4.4.
Official, national and regional antimicrobial policies should be taken into account
when the veterinary medicinal product is used.
Use of the veterinary medicinal product deviating from the instructions given in the
SPC may increase the prevalence of bacteria resistant to lincomycin and may
decrease the effectiveness of treatment with other lincosamides, macrolides or
streptogramin B due to potential for cross-resistance.
Repeated or prolonged use should be avoided by improving the farm management
and hygiene practices.
Special precautions to be taken by the person administering the veterinary
medicinal product to animals
This product contains lincomycin and lactose monohydrate, either of which can
cause allergic reactions in some people. People with known hypersensitivity to
lincomycin or any other lincosamide, or to lactose monohydrate, should avoid
contact with the veterinary medicinal product.
Care should be taken not to raise and inhale any dust.
Contact with skin and eyes should be avoided.
Personal protective equipment consisting of approved dust masks (either a
disposable half-mask respirator conforming to European Standard EN 149 or a non-
disposable respirator conforming to European Standard EN 140 with a filter to EN
143), gloves and safety glasses should be worn when handling and mixing the
product. If respiratory symptoms develop following exposure, seek medical advice
and show this warning to the physician.
In case of accidental exposure to the skin, eyes or mucous membranes, wash the
affected area
persistent eye irritation appear after exposure, seek medical advice immediately and
show the package leaflet or label to the physician.
Wash hands and any exposed skin with soap and water immediately after use.

Revised January 2025
AN: 00963/2024 + 01298/2024Page 3 of 7
Do not eat, drink or smoke while handling the product.
Other precautions
Lincomycin is known to be toxic to terrestrial plants, cyanobacteria and
groundwater bacteria.

interaction
Antagonism may exist between lincomycin and macrolides such as erythromycin
and other bactericidal antibiotics; concurrent use is therefore not recommended due
to competitive binding at the 50S ribosomal subunit of the bacterial cell.
The bioavailability of lincomycin may decrease in the presence of gastric antacids or
activated charcoal, pectin or kaolin.
Lincomycin can potentiate neuromuscular effects of anaesthetic and muscle
relaxants.

This veterinary medicinal product does not require any special storage conditions.

Pigs
Meat and offal: 1 day.

Revised January 2025
AN: 00963/2024 + 01298/2024Page 5 of 7
Chickens
Meat and offal: 5 days
Not authorised for use in laying birds producing eggs for human consumption.
5.

This information is sourced from the official Summary of Product Characteristics (SPC) published by the Veterinary Medicines Directorate (VMD). It is provided for informational purposes only and does not replace professional veterinary advice. Always consult your vet before administering any medication.