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POM-V Prescription Required

Linco-Spectin 100, 222/444.7 mg/g Powder for Use in Drinking Water for Pigs and Chickens

Active ingredients: Lincomycin, Spectinomycin

Form

Powder

Species

Chickens Pigs

Manufacturer

Phibro Animal Health (Poland) Sp z.o.o.

VMD MA No.

61652/3003

What it's used for

Chickens: For the treatment and metaphylaxis of chronic respiratory disease (CRD) caused by Mycoplasma gallisepticum and Escherichia coli susceptible to li...

Full indications, dosage and side effects ↓
View official SPC (PDF)

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Clinical information

Linco-Spectin 100, 222/444.7 mg/g Powder for Use in Drinking Water for Pigs and Chickens — SPC Details

Source: VMD Summary of Product Characteristics (SPC). Last updated 27 Mar 2026.

Chickens:
For the treatment and metaphylaxis of chronic respiratory disease (CRD) caused by
Mycoplasma gallisepticum and Escherichia coli susceptible to lincomycin and
spectinomycin, and associated with a low mortality rate.
The presence of the disease in the flock must be established before the veterinary
medicinal product is used.

Amended pages: January 2026
The recommended dosage rates are:
Pigs: 3.33 mg lincomycin and 6.67 mg spectinomycin/kg bw/day, for 7 days. This
amounts to 15 mg powder/kg bw/day for 7 days.
In pigs 150 g of the veterinary medicinal product corresponds to the dose for 10,000
kg of body weight per day.
Based on the recommended dose and the number and weight of animals to be
treated, the exact daily concentration of the veterinary medicinal product should be
calculated according to the following formula:
10,000 x [daily water consumption per animal
(L)]
Volume (L) for 150 g of the
veterinary medicinal
product
=
average body weight of one pig (kg)
As an indication, standard water intake varies around 0.15 L/kg bw/day. The table
below shows the volume of water to be used for dissolution of 150 g of the veterinary
medicinal product.

Amended pages: January 2026
Water
consumption
150 g of powder = 100 g antibiotic activity should be dissolved
in…
0.1 L/kg bw/day1,000 L of drinking water0.15 L/kg bw/day1,500 L of drinking water0.2 L/kg bw/day2,000 L of drinking water0.25 L/kg bw/day2,500 L of drinking water
Chickens: 16.65 mg lincomycin and 33.35 mg spectinomycin/kg bw/day, for 7 days.
This amounts to 75 mg powder/kg bw/day for 7 days.
In chickens 150 g of the veterinary medicinal product corresponds to the dose for
2,000 kg of body weight per day.
Based on the recommended dose and the number and weight of animals to be
treated, the exact daily concentration of the veterinary medicinal product should be
calculated according to the following formula:
2,000 x [daily water consumption per bird (L)]Volume (L) for 150 g of
the veterinary medicinal
product
=
average body weight of one bird (kg)
Treatment should be initiated as soon as first clinical signs occur.
For the preparation of drinking water, the incorporation rate of the veterinary
medicinal product in water will depend on the body weight of the animals and their
actual daily intake of water.
To ensure a correct dosage and avoid underdosing, mean body weights in the group
of animals and daily water consumption should be determined as accurately as
possible.
The medicated drinking water should be the sole source of drinking water for the
treatment duration. Any medicated water which is not consumed within 24 hours
should be discarded.
In case of disease accompanied with significant decrease in water intake, parenteral
treatment may have to be initiated.
Use the following indications as a basis for the precise calculation of incorporation
rate of the veterinary medicinal product in drinking water.
Do not use in cases of hypersensitivity to the active substances or to any of the
excipients.
Do not use in case of hepatic dysfunction.
Do not allow rabbits, rodents (e.g. chinchillas, hamsters, guinea pigs), horses or
ruminants to access to water or feeds containing lincomycin. Ingestion by these
species may result in severe gastrointestinal effects.
Do not use in laying hens.
Chickens:
Rare
(1 to 10 animals / 10,000
animals treated):
Allergic reaction
, Hypersensitivity reaction
1
Require stopping treatment with the veterinary medicinal product. Symptomatic
treatment must be implemented.
Pigs:
Very common
(>1 animal / 10 animals
treated):
Diarrhoea
, Loose stool
Skin inflammation
1,2
Rare
(1 to 10 animals / 10,000
animals treated):
Excitation, Irritability
Allergic reaction
, Hypersensitivity reaction
Pruritus, Rash
Usually self-correcting within 5-8 days without discontinuing the treatment.
Affecting perianal region.
Require stopping treatment with the veterinary medicinal product. Symptomatic
treatment must be implemented.
Reporting adverse events is important. It allows continuous safety monitoring of a
veterinary medicinal product. Reports should be sent, preferably via a veterinarian, to
either the marketing authorisation holder <or its local representative> or the national
competent authority via the national reporting system. See the package leaflet for
respective contact details.

Amended pages: January 2026
In Escherichia coli, a significant part of the strains show high MIC values (minimum
inhibitory concentrations) against the lincomycin-spectinomycin combination and may
be clinically resistant, although no breakpoint is defined.
Due to technical constraints the susceptibility of Lawsonia intracellularis is difficult to
test in vitro, and data about the lincomycin-spectinomycin resistance status in that
species are lacking.

Special precautions for safe use in the target species:
It is sound clinical practice to base treatment on susceptibility testing of the bacteria
isolated from the animal. If this is not possible, therapy should be based on local
(regional, farm level) epidemiological information about susceptibility of target
bacteria.
Use of the veterinary medicinal product deviating from the instructions in the SPC
may increase the risk of development and selection of resistant bacteria and
decrease the effectiveness of treatment with macrolides due to the potential for
cross-resistance.
The oral use of preparations containing lincomycin is only indicated in swine and
chickens.
Do not leave access to the medicated water for other animals. Lincomycin may lead
to severe gastrointestinal disturbances in other animal species.
The repeated or prolonged use should be avoided, by improving the farm
management and disinfection practices.
Diagnosis should be reconsidered if improvement is not seen after 5 days.
Sick animals have a reduced appetite and an altered drinking pattern, and severely
affected animals may therefore require parenteral treatment.
This powder is for use in drinking water only and should be dissolved before use.

Amended pages: January 2026
Special precautions to be taken by the person administering the veterinary medicinal
product to animals:
People with known hypersensitivity to lincomycin, spectinomycin or soybean millfeed
should avoid contact with the veterinary medicinal product. Care should be taken not
to raise and inhale any dust.
Contact with skin and eyes should be avoided.
Personal protective equipment consisting of approved dust masks (either a
disposable half mask respirator conforming to European Standard EN149 or a non-
disposable respirator conforming to European Standard EN 140 with a filter EN 143),
gloves and safety glasses should be worn when handling and mixing the veterinary
medicinal product.
Wash hands and any exposed skin with soap and water immediately after use.
If symptoms such as skin rash or persistent eye irritation appear after exposure, seek
medical advice immediately and show the package leaflet or label to the physician.
Special precautions for the protection of the environment:
Not applicable.
In general mixture with other medicines should be avoided.
The combination of lincosamides and macrolides is antagonistic, due to competitive
binding to their target sites. Combination with anaesthetics may lead to possible
neuromuscular blocking.
Do not administer with kaolin or pectin as they impair lincomycin absorption. If co-
administration is mandatory, respect a delay of two hours between intakes.
This veterinary medicinal product does not require any special storage conditions.

Amended pages: January 2026
Pigs:
Meat and offal: Zero days.
Chickens:
Meat and offal: 5 days.
Not for use in birds producing or intended to produce eggs for human consumption.

This information is sourced from the official Summary of Product Characteristics (SPC) published by the Veterinary Medicines Directorate (VMD). It is provided for informational purposes only and does not replace professional veterinary advice. Always consult your vet before administering any medication.

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