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POM-V Prescription Required

Linco-Sol 400 mg/g Powder for Use in Drinking Water for Pigs and Chickens

Active ingredient: Lincomycin

Form

Powder

Species

Chickens Pigs

Manufacturer

Lavet Pharmaceuticals Ltd

VMD MA No.

32823/4005

What it's used for

Pigs Treatment and metaphylaxis of enzootic pneumonia caused by Mycoplasma hyopneumoniae. The presence of the disease in the group must be established befo...

Full indications, dosage and side effects ↓
View official SPC (PDF)

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Prescription required

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Clinical information

Linco-Sol 400 mg/g Powder for Use in Drinking Water for Pigs and Chickens — SPC Details

Source: VMD Summary of Product Characteristics (SPC). Last updated 26 Mar 2026.

Pigs
Treatment and metaphylaxis of enzootic pneumonia caused by Mycoplasma
hyopneumoniae.
The presence of the disease in the group must be established before the product is used.
Chickens
Treatment and metaphylaxis of necrotic enteritis caused by Clostridium perfringens.
The presence of the disease in the group must be established before the product is used.
For use in drinking water.
Dosage:
Swine:
Enzootic pneumonia: 10 mg lincomycin per kg of body weight for 21 consecutive days.
Chicken (boiler)
Necrotic enteritis:
consecutive days.
Administration:
To be administered orally, in the drinking water.
Swine:
The product should be administered continuously in the drinking water. In pigs,
administration of 33 mg lincomycin per litre containing to the completion of drinking water
by dissolving 100 g of product in 1200 litres of water. When using a water proportioner,
prepare a stock solution by dissolving 100 g of product in 12 litres of water. Set the
proportioner to deliver 10 ml of stock solution per litre of drinking water.
Chicken (broiler):
The concentration to be used depends on the actual body weight and the water
consumption of the animals and can be calculated as follows:
.....mg product
per kg body weight and dayx
Average chicken
body weight (kg)Average daily water intake (litre/animal)=....mg product per litre of
drinking water
To ensure a correct dosage body weight should be determined as accurately as possible
to avoid underdosing. The intake of medicated water depends on the physiological and
clinical condition of the animals. In order to obtain the correct dosage the concentration of

Revised: July 2021
AN: 00290/2021 and 00292/2021
Lincomycin has to be adjusted accordingly. The uptake of water should be monitored
frequently.
The medicated water should be the only source of drinking water, throughout the treatment
period. Medicated water should be refreshed every 24 hours. After the end of the
medication period, the water supply system should be cleaned appropriately to avoid
intake of sub-therapeutic amounts of the active substance.
Do not use in cases of hypersensitivity to the active substance or to any of the excipients.
Do not use if resistance to lincosamides has been detected.
Do not administer to horses, ruminants, guinea pigs, hamsters, chinchilla and rabbits.
Ingestion by these species may result in severe gastrointestinal effects.
Do not use in cases of hepatic dysfunction.
On rare occasions Lincomycin may cause transient soft stools and/or mild swelling of the
anus within the first two days of treatment in pigs. On rare occasions some pigs may show
reddening of skin and mild irritable behaviour. These conditions are usually self-correcting
within 5-8 days without discontinuing lincomycin treatment. Allergic/hypersensitive
reactions occur on rare occasions.
The frequency of adverse reactions is defined using the following convention:
- very common (more than 1 in 10 animals treated displaying adverse reactions)
- common (more than 1 but less than 10 animals in 100 animals treated)

Revised: July 2021
AN: 00290/2021 and 00292/2021
- uncommon (more than 1 but less than 10 animals in 1,000 animals treated)
- rare (more than 1 but less than 10 animals in 10,000 animals treated)
- very rare (less than 1 animal in 10,000 animals treated, including isolated reports).
Medicated drinking water uptake can be affected by the severity of the disease. In case of
insufficient uptake of water, animals should be treated parenterally.
The susceptibility of
in vitro

Revised: July 2021
AN: 00290/2021 and 00292/2021
both . Where possible, therapy should be based on
local (regional, farm level) epidemiological information concerning the response of
enzootic pneumonia/necrotic enteritis to treatment with lincomycin.

Special precautions for use in animals
Use of the veterinary medicinal product preferably should be based on identification of the
target pathogen and susceptibility testing of the bacteria isolated from the animal.
However, also see text under section 4.4. Official, national and regional antimicrobial
policies should be taken into account when the veterinary medicinal product is used.
Use of the veterinary medicinal product deviating from the instructions given in the
summary of product characteristics may increase the prevalence of bacteria resistant to
the lincomycin and may decrease the effectiveness of treatment with other lincosamides,
macrolides and streptogramin B due to the potential for cross-resistance.
Repeated or prolonged use should be avoided by improving the farm management and
hygiene practices.
Special precautions to be taken by the person administering the veterinary medicinal
product to animals
This product contains lincomycin and lactose monohydrate, either of which can cause
allergic reactions in some people. People with known hypersensitivity to lincomycin or any
other lincosamide or to lactose monohydrate, should avoid contact with the veterinary
medicinal product.
Care should be taken not to raise and inhale any dust. The wearing of approved dust
masks (either a disposable half-mask respirator conforming to European Standard EN 149
or a non-disposable respirator to European Standard EN 140 with a filter to EN 143),
gloves and safety glasses are recommended whilst reconstituting or administering the
solution.
Direct contact of the product with the skin, eyes and mucous membranes should be
avoided.
In case of accidental exposure to the skin, eyes or mucous membranes, rinse abundantly
with water. In case of allergic reaction (inflammation of the face, lips or eyes or respiratory
difficulties) during reconstituting or administering of the product, seek medical advice
immediately and show the package leaflet or the label to the physician.
Do not smoke, eat or drink when handling the product.
Wash hands and any exposed skin with soap and water immediately after use.
Antagonism may exist between lincomycin and macrolides such as erythromycin and other
bactericidal antibiotics; concurrent use is therefore not recommended due to competitive
binding at the 50S ribosomal subunit of the bacterial cell.
The bioavailability of lincomycin may decrease in the presence of gastric antacids or
activated charcoal, pectin or kaolin.
Lincomycin can potentiate neuromuscular effects of anaesthetics and muscle relaxants.
Do not store above 25C.

Revised: July 2021
AN: 00290/2021 and 00292/2021
Store in the original container tightly closed in order to protect from moisture.
Meat and offal of swine: 1 day
Meat and offal of chicken (broiler): 5 days
Not authorised for use in laying birds producing eggs for human consumption.
5.

This information is sourced from the official Summary of Product Characteristics (SPC) published by the Veterinary Medicines Directorate (VMD). It is provided for informational purposes only and does not replace professional veterinary advice. Always consult your vet before administering any medication.

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