Norofol 10 mg/ml Emulsion for Injection for Cats and Dogs

The product is indicated for intravenous administration to dogs and cats. The vial
should be shaken thoroughly before opening. The product should be inspected
visually for the absence of visible droplets or extraneous foreign particles and
discarded if present.
Induction: The induction dose is calculated according to bodyweight and may be
administered to effect over a period of 10 to 40 seconds. The induction dose is
reduced by the use of premedicants.
Where animals have been premedicated with an -2 agonist such as medetomidine,
the dose of propofol (as with any other intravenous anaesthetic agent) should be
reduced by up to 85% (e.g. from 6.5 mg/kg for unpremedicated dogs to 1.0 mg/kg for
dogs premedicated with an 
The following dose rates are for guidance and in practice the dose rate should be
based on response. The average induction dose for dogs and cats, either
unpremedicated or when premedicated with a
acepromazine or an α-2
Dose
(mg/kg bodyweight)
Dose Volume
(ml/kg bodyweight)
DogsUnpremedicated6.5 mg/kg0.65 ml/kgPremedicated With non-α-2 4.0 mg/kg0.40 ml/kg With α-2 agonist1.0 mg/kg0.10 ml/kgCatsUnpremedicated8.0 mg/kg0.8 ml/kgPremedicated With non-α-2 6.0 mg/kg0.60 ml/kg With α-2 agonist1.2 mg/kg0.12 ml/kg
Maintenance: Where anaesthesia is maintained by incremental injections, the dose
rate will vary between animals. Incremental doses should be given to effect. Doses of
approximately 1.25 – 2.5mg (0.125 – 0.25ml) per kg bodyweight sustain anaesthesia
for periods of up to 5 minutes.
Maintenance by inhalation agents: Where inhalation agents are used to maintain
general anaesthesia, clinical experience indicates that there may be a need to use a
higher initial concentration of inhalation agent than is normally the case following
induction with barbiturate agents such as thiopentone.
Continuous and prolonged exposure may lead to slower recovery, particularly in cats.