Mastic Seal 2.6 Intramammary Suspension for Cattle
Active ingredient: Bismuth Subnitrate
Form
Intramammary
Species
Manufacturer
Bioveta, a.s.
VMD MA No.
46608/3003
What it's used for
In cows considered likely to be free of subclinical mastitis, the veterinary medicinal product can be used on its own in dry cow management and mastitis co...
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Prescription required
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Mastic Seal 2.6 Intramammary Suspension for Cattle — SPC Details
Source: VMD Summary of Product Characteristics (SPC). Last updated 27 Mar 2026.
product can be used on its own in dry cow management and mastitis control.
into each udder quarter immediately after the last milking of the lactation (at drying-
off). Do not massage the teat or udder after infusion of the product because it is
important that the sealant stays in the teat itself and does not enter the udder. It is
recommended to compress the teat at its base during application.
Care must be taken not to introduce pathogens into the teat in order to reduce the risk
of post-infusion mastitis.
As the veterinary medicinal product does not have antimicrobial activity, it is essential
that the teat is thoroughly cleaned and disinfected before infusion with the alcohol-
impregnated wipes provided or other suitable technique. The teats should be wiped
until there is no visible dirt collected on the wipe. The teats should be allowed to dry
prior to infusion. Infuse aseptically and take care to avoid contamination of the
intramammary syringe nozzle. Following infusion, it is advisable to use an appropriate
teat dip or spray.
Under cold conditions the veterinary medicinal product may be warmed to room
temperature in a warm environment without the risk of its contamination, to aid
syringeability.
Do not use the veterinary medicinal product alone in cows with sub-clinical mastitis at
drying off.
Do not use in cows with clinical mastitis at drying off.
Do not use in cases of hypersensitivity to the active substances or to any of the
excipients.
Very rare
(<1 animal / 10,000 animals
treated, including isolated
reports):
acute mastitis*
* these symptoms are mainly caused by poor infusion technique and poor hygiene.
The importance of aseptic technique is described in sections 3.5 and 3.9.
Reporting adverse events is important. It allows continuous safety monitoring of a
veterinary medicinal product. Reports should be sent, preferably via a veterinarian, to
either the marketing authorisation holder or its local representative or the national
competent authority via the national reporting system. See the package leaflet for
respective contact details.
management to prevent new intramammary infections. Selection of cows for treatment
with the veterinary medicinal product should be based on veterinary clinical judgement.
Selection criteria may be based on the mastitis and somatic cells count history in
individual cows or recognised tests for the detection of subclinical mastitis or
bacteriology sampling.
Special precautions for safe use in the target species:
It is advisable to observe dry cows regularly for possible signs of clinical mastitis. If a
sealed quarter develops clinical mastitis, the affected quarter should be stripped out
manually before appropriate antibiotic therapy is instituted.
To avoid contamination, do not immerse the intramammary syringe in water. Use the
intramammary syringe only once.
Since the veterinary medicinal product does not have antimicrobial activity, in order to
minimize the risk of acute mastitis due to poor infusion technique and lack of hygiene
(see section 3.6), it is crucial to follow the aseptic technique of administration described
in section 3.9.
Do not administer any other intramammary product following administration of the
veterinary medicinal product. In cows that may have sub-clinical mastitis, the veterinary
medicinal product may be used following administration of a suitable dry cow antibiotic
treatment to the infected quarter.
Special precautions to be taken by the person administering the veterinary medicinal
product to animals:
People with known hypersensitivity to bismuth salts or paraffin should avoid contact
with the veterinary medicinal product.
This veterinary medicinal product may cause skin and eye irritation. Avoid contact with
skin or eyes.
Personal protective equipment consisting of rubber gloves should be worn when
handling the veterinary medicinal product.
Should skin or eye contact occur, wash the affected area thoroughly with water. If
irritation persists, seek medical advice and show the package leaflet or the label to the
physician.
Cleaning wipes: contain isopropyl alcohol and may therefore cause skin and eye
irritation. Avoid contact with eyes. Avoid prolonged contact with skin.
Wash hands after use.
Special precautions for the protection of the environment:
Not applicable.
demonstrated with a cloxacillin-containing dry cow veterinary medicinal product. See
also section 3.5 “Special precautions for safe use in the target species”.
Protect from light.
Milk: Zero hours.
This information is sourced from the official Summary of Product Characteristics (SPC) published by the Veterinary Medicines Directorate (VMD). It is provided for informational purposes only and does not replace professional veterinary advice. Always consult your vet before administering any medication.
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Other Products Containing Bismuth Subnitrate
These products share the same active ingredient and may be suitable alternatives. Always consult your vet.
Cepralock 2.6 g Intramammary Suspension for Dry Cows
POM-VIntervet International B.V.
Cepralock 2.6 g Intramammary Suspension for Dry Cows
POM-VIntervet International B.V.
DrySeal 2.6 g Intramammary Suspension for Cattle
POM-VElanco GmbH
DrySeal 2.6 g Intramammary Suspension for Cattle
POM-VElanco Europe Ltd
Fatroseal 2.6 g Intramammary Suspension for Dry Cows
POM-VFatro S.p.A.
Fatroseal 2.6 g Intramammary Suspension for Dry Cows
POM-VFatro S.p.A.
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