POM-V Prescription Required

Lyncoo 400 mg/g Powder for Use in Drinking Water for Pigs and Chickens

Active ingredient: Lincomycin

Form

Powder

Species

Chicken Pigs

Manufacturer

Endectovet EOOD

VMD MA No.

60125/3000

What it's used for

The presence of the disease in the group must be established before the veterinary medicinal product is used. Chickens Treatment and metaphylaxis of necrot...

Full indications, dosage and side effects ↓

View official SPC (PDF)

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Paying less for Lincomycin

1

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They must provide one on request. Under the CMA Order the fee is capped at £21 from 2027.
2

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The CMA found online pharmacies 50–60% cheaper than practice dispensing on common medicines — typically £200–£300 a year.

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Prescription required

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Clinical information

Lyncoo 400 mg/g Powder for Use in Drinking Water for Pigs and Chickens — SPC Details

Source: VMD Summary of Product Characteristics (SPC). Last updated 27 Mar 2026.

The presence of the disease in the group must be established before the veterinary
medicinal product is used.
Chickens
Treatment and metaphylaxis of necrotic enteritis caused by Clostridium perfringens.
The presence of the disease in the flock must be established before the veterinary
medicinal product is used.

The recommended dosage rates are:
Pigs:
Enzootic pneumonia: 10 mg lincomycin per kg of body weight (corresponding to 25
mg veterinary medicinal product per kg bodyweight) for 21 consecutive days.
Chickens:
Necrotic enteritis: 5 mg lincomycin per kg of body weight (corresponding to 12.5 mg
veterinary medicinal product per kg bodyweight) for 7 consecutive days.
To ensure a correct dosage, body weights should be determined as accurately as
possible.
The intake of medicated water depends on the clinical condition of the animals. In
order to obtain the correct dosage, the concentration of lincomycin may need to be
adjusted accordingly.
The use of suitably calibrated weighing equipment is recommended. The uptake of
water should be monitored frequently.
Based on the recommended dose and the number and weight of animals to be
treated, the exact daily concentration of the veterinary medicinal product should be
calculated according to the following formula:
mg veterinary medicinal
product / kg body weight
per dayX
average body weight
(kg) of animals to be
treated
average daily water intake (L/animal)
= mg of veterinary
medicinal product per
litre of drinking water
Complete dissolution of the veterinary medicinal product should be ensured.
The maximum solubility of the veterinary medicinal product in soft/hard water is 50
g/L at 20°C and 15 g/L at 5°C.
For stock solutions and when using a proportioner, take care not to exceed the
maximum solubility which can be achieved under the given conditions. Adjust the
flow rate setting of the dosing pump according to concentration of the stock solution
and water intake of the animals to be treated.
The medicated water should be the only source of drinking water for the animals for
the entire duration of the treatment period.
The daily amount is to be added to the drinking water in such a way that all medication
will be consumed within 24 hours. Medicated drinking water should be freshly
prepared every 24 hours. No other source of drinking water should be available.
After the end of the medication period, the water supply system should be cleaned
appropriately to avoid intake of sub-therapeutic amounts of the active substance.
In regards to biocide compatibility, please see section 5.1.

Do not use in cases of hypersensitivity to the active substance or to any of the
excipient.
Do not administer, and do not allow access to water containing lincomycin, to
rabbits, hamsters, guinea pigs, chinchillas, horses or ruminants as this could result in
severe gastro-intestinal disturbance.
Do not use in cases of known resistance to lincosamides.
Do not use in cases of hepatic dysfunction.
AN: 02055/2024 & 02058/2024

Pigs:
Rare
(1 to 10 animals / 10,000 animals
treated):
Irritability
1, 2
Diarrhoea
Hypersensitivity reaction, Anal oedema
(swelling)
3, 4
Reddening of the skin
1
Usually self-correcting within 5-8 days without discontinuing the lincomycin
treatment
Mild, behavioural.
Within the first 2 days after onset the treatment.
Mild
Chickens:
None known.
Reporting adverse events is important. It allows continuous safety monitoring of a
veterinary medicinal product. Reports should be sent, preferably via a veterinarian,
to either the marketing authorisation holder or its local representative or the national
competent authority via the national reporting system. See the package leaflet for
respective contact details.

Medicated drinking water uptake can be affected by the severity of the disease. In
case of insufficient uptake of water, pigs should be treated parenterally.
Cross-resistance has been shown between lincomycin and different antimicrobials
including other lincosamides, macrolides and streptogramin B antibiotics. Use of the
veterinary medicinal product should be carefully considered when susceptibility testing
has shown resistance to lincosamides, macrolides and streptogramin B because its
effectiveness may be reduced.

Special precautions for safe use in the target species:
Use of the veterinary medicinal product should be based on identification and
susceptibility testing of the target pathogen(s). The susceptibility of
hyopneumoniae to antimicrobial agents is difficult to test owing to technical
constraints. In addition, there is a lack of clinical breakpoints for both
hyopneumoniae and . Thus, if this is not possible, therapy should be
based on epidemiological information and knowledge of susceptibility of the target
pathogens at farm level, or at local/regional level. Use of the veterinary medicinal
product should be in accordance with official, national and regional antimicrobial
policies.
An antibiotic with a lower risk of antimicrobial resistance selection (lower AMEG
category) should be used for first line treatment where susceptibility testing suggests
the likely efficacy of this approach. Repeated or prolonged use should be avoided by
improving the farm management and hygiene practices.
Antimicrobial medicinal products shall be used for metaphylaxis only when the risk of
spread of an infection or of an infectious disease in the group of animals is high and
where no other appropriate alternatives are available.
Special precautions to be taken by the person administering the veterinary medicinal
product to animals:
This veterinary medicinal product contains lincomycin and lactose monohydrate, either
of which can cause allergic reactions in some people. People with known
hypersensitivity to lincomycin or any other lincosamide, or to lactose monohydrate,
should avoid contact with the veterinary medicinal product.
Care should be taken not to raise and inhale any dust.
Contact with skin and eyes should be avoided.
Personal protective equipment consisting of approved dust masks (either a disposable
half mask respirator conforming to European Standard EN149 or a non-disposable
respirator conforming to European Standard EN140 with a filter EN143), gloves and
safety glasses should be worn when handling and mixing the veterinary medicinal
product. If respiratory symptoms develop following exposure,
seek medical advice and show this warning to the physician.
In case of accidental exposure to the skin, eyes or mucous membranes, wash the
affected area thoroughly with plenty of water.
If symptoms such as skin rash or persistent eye irritation appear after exposure, seek
medical advice immediately and show the package leaflet or label to the physician.
Wash hands and any exposed skin with soap and water immediately after use.
AN: 02055/2024 & 02058/2024
Do not eat, drink or smoke while handling the veterinary medicinal product. In case
of accidental ingestion, seek medical advice immediately and show the package
leaflet or the label to the physician.
Special precautions for the protection of the environment:
Not applicable.

Antagonism may exist between lincomycin and macrolides such as erythromycin and
other bactericidal antibiotics; concurrent use is therefore not recommended due to
competitive binding at the 50S ribosomal subunit of the bacterial cell.
The bioavailability of lincomycin may decrease in the presence of gastric antacids or
activated charcoal, pectin or kaolin.
Lincomycin can potentiate neuromuscular effects of anaesthetics and muscle
relaxants.

This veterinary medicinal product does not require any special storage conditions.

Pigs:
Meat and offal: 1 day.
Chickens:
Meat and offal: 5 days.
Not for use in birds producing or intended to produce eggs for human consumption.

This information is sourced from the official Summary of Product Characteristics (SPC) published by the Veterinary Medicines Directorate (VMD). It is provided for informational purposes only and does not replace professional veterinary advice. Always consult your vet before administering any medication.