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AVM-GSL Over the Counter Companion Animal

Johnson's 4 Fleas Protector 60 mg Spot-on Solution for Cats and Kittens

Active ingredient: Pyriproxyfen

Form

Spot-on

Species

Cats

Manufacturer

Alfamed

VMD MA No.

17902/4012

What it's used for

Prevention of flea multiplication (adult and larval stages of sensitive to pyriproxyfen) in cats by inhibiting egg development for 3 months.

Full indications, dosage and side effects ↓
View official SPC (PDF)

The prescription itself has a price. See what practices near you charge for a consultation and the written prescription fee.

Paying less for Pyriproxyfen

  1. 1

    Ask your vet for a written prescription

    They must provide one on request. Under the CMA Order the fee is capped at £21 from 2027.

  2. 2

    Fill it at a registered online retailer

    The CMA found online pharmacies 50–60% cheaper than practice dispensing on common medicines — typically £200–£300 a year.

Clinical information

Johnson's 4 Fleas Protector 60 mg Spot-on Solution for Cats and Kittens — SPC Details

Source: VMD Summary of Product Characteristics (SPC). Last updated 26 Mar 2026.

Prevention of flea multiplication (adult and larval stages of
sensitive to pyriproxyfen) in cats by inhibiting egg development for 3 months.
Single administration of one pipette per cat (equivalent to a minimal dosage of 10 mg
per kg of bodyweight). This dosage may be achieved by applying one pipette of 0.6
ml for a cat weighing between 1 kg and 6 kg.
Johnson’s 4 Fleas Protector 60 mg for Cats and Kittens should be administered
directly on the skin of the animal, at the base of the neck. Care should be taken to

Revised: July 2012
AN. 01668/2011
maintain contact between the pipette and skin during the administration of the
product. Apply the contents by carefully squeezing the bottom of the tube 4 times.
A second application can be made 3 months after the first one to prolong efficacy for
a further 3 months.
Do not use in kittens weighing less than 1 kg.
Do not use if your cat is unwell or recovering from an illness.
Among the rare suspected adverse reactions, transient cutaneous reactions on the
application site (squamosis, local alopecia, pruritus, erythema) and general pruritus
or alopecia have been reported after use. Exceptionally, hypersalivation or vomiting
have been observed after treatment.
Fleas should be removed from lactating females and young kittens by careful use of
a flea comb.
In case several animals are part of the same household, appropriate treatment
should be carried out for each animal. As for any parasiticidal product, its frequent

Revised: July 2012
AN. 01668/2011
and repeated use may cause the development of parasite resistance to the active
ingredient.
Infestations occurring during the initial administration or appearing during the
treatment period may be eliminated with appropriate medicinal insecticides.
The influence of bathing or wetting immediately after treatment has not been
evaluated. Therefore, it is likely that the efficacy will be reduced if the animal is
wetted or shampooed immediately after the treatment.

(i) Special precautions for use in animals
For external use only.
(ii) Special precautions to be taken by the person administering the veterinary
medicinal products to animals
Avoid contact with skin and eyes. In case of accidental contact, rinse abundantly with
water.
In case of eye irritation, seek medical attention.
Wash hands after use.
From clinical field studies, no interaction was observed between organophosphate or
pyrethroid compounds and pyriproxyfen.
No special precautions for storage.
Not applicable.
5.

This information is sourced from the official Summary of Product Characteristics (SPC) published by the Veterinary Medicines Directorate (VMD). It is provided for informational purposes only and does not replace professional veterinary advice. Always consult your vet before administering any medication.

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