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AVM-GSL Over the Counter Companion Animal

Johnson's 4 Fleas Protector 12 mg Spot-on Solution for Puppies and Small Dogs

Active ingredient: Pyriproxyfen

Form

Spot-on

Species

Dogs

Manufacturer

Alfamed

VMD MA No.

17902/4013

What it's used for

Prevention of flea multiplication (adult and larval stages of sensitive to pyriproxyfen) in dogs weighing from 0.6 kg up to 6 kg by inhibiting egg developm...

Full indications, dosage and side effects ↓
View official SPC (PDF)

The prescription itself has a price. See what practices near you charge for a consultation and the written prescription fee.

Paying less for Pyriproxyfen

  1. 1

    Ask your vet for a written prescription

    They must provide one on request. Under the CMA Order the fee is capped at £21 from 2027.

  2. 2

    Fill it at a registered online retailer

    The CMA found online pharmacies 50–60% cheaper than practice dispensing on common medicines — typically £200–£300 a year.

Clinical information

Johnson's 4 Fleas Protector 12 mg Spot-on Solution for Puppies and Small Dogs — SPC Details

Source: VMD Summary of Product Characteristics (SPC). Last updated 26 Mar 2026.

Prevention of flea multiplication (adult and larval stages of
sensitive to pyriproxyfen) in dogs weighing from 0.6 kg up to 6 kg by inhibiting egg
development for 3 months.
Single administration of one pipette per dog (equivalent to a minimal dosage of 2 mg
per kg of bodyweight). This dosage may be achieved by applying one pipette of 0.6
ml for a dog weighing from 0.6 kg up to 6 kg.
Johnson’s 4 Fleas Protector 12 mg for Puppies and Small Dogs should be
administered directly on the skin of the animal, at the base of the neck. Care should
be taken to maintain contact between the pipette and skin during the administration
of the product. Apply the contents by carefully squeezing the bottom of the tube 4
times.
A second application can be made 3 months after the first one to prolong efficacy for
a further 3 months.
Do not use in puppies less than 1 month of age.
Do not use if your dog is unwell or recovering from an illness.
Among the very rare suspected adverse reactions, transient cutaneous reactions
such as pruritus, erythema have been observed after use in dogs.
Fleas should be removed from lactating females and young puppies by careful use of
a flea comb.

Revised: July 2012
AN. 01671/2011
In case several animals are part of the same household, appropriate treatment
should be carried out for each animal. As for any parasiticidal product, its frequent
and repeated use may cause the development of parasite resistance to the active
ingredient.
Infestations occurring during the initial administration or appearing during the
treatment period may be eliminated with appropriate medicinal insecticides.
The influence of bathing or wetting immediately after treatment has not been
evaluated. Therefore, the efficacy may be reduced if the animal is wetted or
shampooed up to 3 days after the treatment.

(i) Special precautions for use in animals
For external use only.
(ii) Special precautions to be taken by the person administering the veterinary
medicinal products to animals
Avoid contact with skin and eyes. In case of accidental contact, rinse abundantly with
water.
In case of eye irritation, seek medical attention.
Wash hands after use.
(iii) Other precautions
Prevent dogs from swimming in ponds and waterways for up to three days after the
treatment.
From clinical field studies, no interaction was observed between organophosphate or
pyrethroid compounds and pyriproxyfen.

Revised: July 2012
AN. 01671/2011
No special precautions for storage.
Not applicable.
5.

This information is sourced from the official Summary of Product Characteristics (SPC) published by the Veterinary Medicines Directorate (VMD). It is provided for informational purposes only and does not replace professional veterinary advice. Always consult your vet before administering any medication.

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