POM-V Prescription Required

Hypersol 500 mg/g Powder for Use in Drinking Water

Active ingredient: Oxytetracycline

Form

Powder

Species

Chickens Pigs

Manufacturer

Huvepharma SA

VMD MA No.

41623/3001

What it's used for

The presence of disease in the group should be established before the veterinary medicinal product is used.

Full indications, dosage and side effects ↓

View official SPC (PDF)

The prescription itself has a price. See what practices near you charge for a consultation and the written prescription fee.

Paying less for Oxytetracycline

1

Ask your vet for a written prescription

They must provide one on request. Under the CMA Order the fee is capped at £21 from 2027.
2

Fill it at a registered online retailer

The CMA found online pharmacies 50–60% cheaper than practice dispensing on common medicines — typically £200–£300 a year.

Your prescription rights → VMD register of retailers →

Prescription required

Your vet must provide a written prescription on request. You can then purchase from any licensed online retailer.

Clinical information

Hypersol 500 mg/g Powder for Use in Drinking Water — SPC Details

Source: VMD Summary of Product Characteristics (SPC). Last updated 27 Mar 2026.

The presence of disease in the group should be established before the veterinary
medicinal product is used.

Revised : May 2025
AN : 03580/2024
The uptake of medicated drinking water depends on the clinical and physiological
conditions of the animals. In order to obtain the correct dosage, the concentration of
oxytetracycline must be adjusted by calculating the required mean daily water
consumption.
The duration of treatment is 3 to 5 days, for both chickens and pigs.
Dosing is presented in the following table:
Species
Expressed in
mg of
oxytetracycline
/ kg of
bodyweight /
day
Expressed in mg
of ORAL
POWDER / 10 kg
of bodyweight /
day
Estimated
water
consumption
(L / kg of
bodyweight)
Expressed in
mg of ORAL
POWDER / L
of drinking
water
Pigs20 mg
400 mg of ORAL
POWDER
1 L / 10 kg of
bodyweight
400 mg of
ORAL
POWDER
Chickens20 mg
400 mg of ORAL
POWDER
1 L / 5 kg of
bodyweight
200 mg of
ORAL
POWDER
Based on the recommended dose, and the number and weight of the animals to be
treated, the exact daily amount of oxytetracycline should be calculated according to
the following formula:
mg of veterinary medicinal
product/
kg body weight / day
x
average body
weight (kg) of
animals to be
treated
average daily water consumption (L/animal)
= mg veterinary
medicinal product per
litre of drinking water
To ensure a correct dosage, body weight should be determined as accurately as
possible.
The use of suitability calibrated weighing equipment is recommended if part packs are
used. The daily amount is to be added to the drinking water such that all medication
will be consumed in 24 hours.
Medicated drinking water should be freshly prepared every 24 hours.
For full advantages of solubility qualities, it is recommended to prepare a concentrated
pre-solution – approximately 400 grams veterinary medicinal product per litre drinking
water – and to dilute this further to therapeutic concentrations if required. Alternatively,
the concentrated solution can be used in a proportional water medicator.

Do not use in cases of hypersensitivity to oxytetracycline or any other substance from
tetracyclines group.
Do not use in cases of known tetracycline resistance.

Chickens and pigs:
Very rare
(<1 animal / 10,000 animals
treated, including isolated
reports):
Allergic and photosensitivity reactions
Undetermined frequency
(cannot be estimated from the
available data).
Digestive tract disorder
1
Common effect for all tetracyclines.
Reporting adverse events is important. It allows continuous safety monitoring of a
veterinary medicinal product. Reports should be sent, preferably via a veterinarian, to
either the marketing authorisation holder or its local representative or the national
competent authority via the national reporting system. See the package leaflet for
respective contact details.

None.

Revised : May 2025
AN : 03580/2024

Special precautions for safe use in the target species:
This powder should be dissolved in water, before use.
Use of the veterinary medicinal product should be based on identification and
susceptibility testing of the target pathogen(s). If not possible, therapy should be based
on local epidemiological information and knowledge of susceptibility of the target
pathogens at farm level, or at local/regional level.
Use of the veterinary medicinal product should be in accordance with official, national
and regional antimicrobial policies. Use of the veterinary medicinal product deviating
from the instructions given in the SPC may increase the prevalence of bacteria
resistant to the oxytetracycline and may decrease the effectiveness of treatment with
tetracyclines, due to the potential for cross-resistance.
Prolonged or repeated use should be avoided as these practises can enforce
development and spread of the bacterial resistance. This is particularly likely in
enterobacteria and Salmonella spp.
As eradication of the target pathogens may not be achieved, medication should be
combined with good management practices, e.g. good hygiene, proper ventilation, no
overstocking.
Extensive resistance to oxytetracycline has been recognised in porcine and poultry
isolates of strains form , ., ., and
Enterococcus spp. The veterinary medicinal product should only be used where culture
and sensitivity testing have demonstrated that it is likely to be effective.
Sick animals may have a reduced appetite and an altered drinking pattern and should,
if necessary, be medicated parenterally.
Special precautions to be taken by the person administering the medicinal product to
animals:
People with known hypersensitivity to tetracyclines should avoid contact with the
veterinary medicinal product.
Avoid inhaling dust when handling the veterinary medicinal product until complete
solubilisation in water. Use in a well-ventilated area away from draughts.
Avoid contact with skin and eyes.
Personal protective equipment consisting of latex and nitrile gloves, eye protection dust
mask (either a disposal half-mask respirator conforming to European Standard EN 149
or a non-disposable respirator to European Standard EN 140 with a filter to EN 143)
and suitable protective clothing should be worn when handling the veterinary medicinal
product. In case of accidental eye or skin contact, rinse the affected area with large
amounts of clean water. If irritation occurs, seek medical advice immediately and show
the label to the physician.
Swelling of the face, lips or eyes, or difficulty with breathing are more serious symptoms
and require urgent medical attention.
Wash hands and contaminated skin immediately after handling the veterinary
medicinal product.

Revised : May 2025
AN : 03580/2024
Do not smoke, eat or drink while handling the veterinary medicinal product.
Special precautions for the protection of the environment:
Not applicable.

Divalent or trivalent cations (Mg, Fe, Al, Ca) may chelate with tetracyclines. The
tetracylines should not be administered with antacids, gels containing aluminium,
preparations containing vitamins or minerals as insoluble complexes will be formed,
which decreases the absorption of the antibiotic.

For 10 kg bag: Do not store above 25°C
For 1 kg jar, 5 kg bucket and 5 kg bag: These veterinary medicinal products do not
require any special storage conditions.

Pigs:
Meat and offal: 7 days
Chickens:
Meat and offal: 7 days
Eggs: not for use in laying birds producing eggs intended for human consumption

This information is sourced from the official Summary of Product Characteristics (SPC) published by the Veterinary Medicines Directorate (VMD). It is provided for informational purposes only and does not replace professional veterinary advice. Always consult your vet before administering any medication.