POM-V Prescription Required Companion Animal

Engemycin 10% DD Solution for Injection

Active ingredient: Oxytetracycline

Form

Injection

Species

Cats Cattle Dogs Horses Pigs Sheep

Manufacturer

Intervet International B.V.

VMD MA No.

06376/4136

What it's used for

In vitro, oxytetracycline is active against a range of both Gram-positive and Gram- negative micro-organisms including: Streptococcus spp., spp., , parahae...

Full indications, dosage and side effects ↓

View official SPC (PDF)

The prescription itself has a price. See what practices near you charge for a consultation and the written prescription fee.

Paying less for Oxytetracycline

1

Ask your vet for a written prescription

They must provide one on request. Under the CMA Order the fee is capped at £21 from 2027.
2

Fill it at a registered online retailer

The CMA found online pharmacies 50–60% cheaper than practice dispensing on common medicines — typically £200–£300 a year.

Your prescription rights → VMD register of retailers →

Prescription required

Your vet must provide a written prescription on request. You can then purchase from any licensed online retailer.

Clinical information

Engemycin 10% DD Solution for Injection — SPC Details

Source: VMD Summary of Product Characteristics (SPC). Last updated 27 Mar 2026.

In vitro, oxytetracycline is active against a range of both Gram-positive and Gram-
negative micro-organisms including:
Streptococcus spp., spp., ,
parahaemolyticus and and against Chlamydophila abortus, the
causative organism of enzootic abortion in sheep.

24 hour dosage regime:
Large animals: Intramuscular use or intravenous use.
Small animals: Subcutaneous use or intramuscular use.
The recommended dosage rate is 3-10 mg/kg bodyweight (depending on age and
species - see table) by intramuscular or intravenous injection in large animals and by
subcutaneous or intramuscular injection in small animals.
The treatment may be repeated at 24 hour intervals up to 4 times (5 treatments in
total).
Intravenous injections must be given slowly over a period of at least one minute.
Prolonged action dosage regime:
Intramuscular use.
10 or 20 mg/kg bodyweight depending on age and species (see table) by
intramuscular injection only, repeated once after 48-60 hours if required.

Amended pages: November 2025
This dosage regime is not advised for use in horses, dogs or cats.
24 hour dosageProlonged actionAnimalWeight kgDose
mg/kg
Volume mlDose
mg/kg
Volume mlHorse500525Not recommended
Foal1001010
Not recommended
Cow5003151050Calf100882020Sow/boar15057.51015Pig2582205Sheep50842010Lamb2582205Dog10101
Not recommended
Cat5100.5
Not recommended
Prophylactic treatment of enzootic abortion in sheep:
20 mg/kg administered about day 95-100 of gestation. A further treatment may be
given 2-3 weeks later.
Before administration, clean the area of the injection site and swab with spirit. Repeat
doses should be administered at different sites, and the sites massaged well after
injection.
Maximum recommended dose at any one site: 20 ml for cattle, 10 ml for sheep and
pigs.
To ensure a correct dosage, body weight should be determined as accurately as
possible.

Do not administer to horses during concomitant therapy with corticosteroids.
Do not use in cases of hypersensitivity to oxytetracycline or tetracycline antibiotics.

Amended pages: November 2025

Cattle:
Very rare
(<1 animal / 10,000 animals
treated, including isolated reports):
Hypersensitivity reaction
, Anaphylaxis
;
Photosensitivity
1
A
initiated.
May occur if exposure to intense sunlight occurs after treatment.
Horses:
Rare
(1 to 10 animals / 10,000 animals
treated):
Hypersensitivity reaction
Very rare
(<1 animal / 10,000 animals
treated, including isolated reports):
Anaphylaxis
;
Injection site swelling
;
Photosensitivity
1
A veterinarian should be consulted immediately and appropriate treatment should be
initiated.
Following intramuscular administration, transient.
May occur if exposure to intense sunlight occurs after treatment.

Amended pages: November 2025
Sheep, pigs and cats:
Very rare
(<1 animal / 10,000 animals
treated, including isolated reports):
Photosensitivity
1
May occur if exposure to intense sunlight occurs after treatment.
Dogs:
Very rare
(<1 animal / 10,000 animals
treated, including isolated reports):
Injection site swelling
;
Photosensitivity
1
Following subcutaneous administration, transient.
May occur if exposure to intense sunlight occurs after treatment.
Reporting adverse events is important. It allows continuous safety monitoring of a
veterinary medicinal product. Reports should be sent, preferably via a veterinarian, to
either the marketing authorisation holder or its local representative or the national
competent authority via the national reporting system. See the package leaflet for
respective contact details.

None.

Special precautions for safe use in the target species:
As with other tetracyclines, caution should be exercised in treating horses under
stress.
Exercise caution in animals with hepatic or renal impairment.
Not for intravenous administration in dogs or cats.
Special precautions to be taken by the person administering the veterinary medicinal
product to animals:
People with known hypersensitivity to oxytetracycline or tetracycline antibiotics should
avoid contact with the veterinary medicinal product.
Take care to avoid accidental self-injection. In case of accidental self-injection, seek
medical advice immediately and show the package leaflet or the label to the physician.
In case of contact with eyes or skin, wash immediately with plenty of water as irritation
may occur.
Wash hands after use.
Special precautions for the protection of the environment:
Not applicable.

It is not recommended to administer bacteriostatic and bactericidal antibiotics
concurrently.

Do not store above 25 °C.
Do not freeze.
Protect from light.
Keep the container in the outer carton.

24 hour dose
Milk:
Cattle6 days Meat and offal:
Cattle35 days
Sheep14 daysPigs14 days
Prolonged action dose
Milk:
Cattle6 daysMeat and offal:
Cattle21 days
Sheep14 daysPigs10 days
Not for use in sheep producing milk for human consumption.
Not for use in horses intended for human consumption.
Treated horses may never be slaughtered for human consumption.
The horse must have been declared as not intended for human consumption under
national horse passport legislation.

This information is sourced from the official Summary of Product Characteristics (SPC) published by the Veterinary Medicines Directorate (VMD). It is provided for informational purposes only and does not replace professional veterinary advice. Always consult your vet before administering any medication.