POM-V Prescription Required

Cyclosol LA, 200 mg/ml Solution for Injection

Active ingredient: Oxytetracycline

Form

Injection

Species

Cattle Pigs

Manufacturer

Eurovet Animal Health B.V.

VMD MA No.

16849/3009

What it's used for

Pigs: For the treatment of respiratory infections caused by oxytetracycline susceptible organisms such as Pasteurella Multocida.

Full indications, dosage and side effects ↓

View official SPC (PDF)

The prescription itself has a price. See what practices near you charge for a consultation and the written prescription fee.

Paying less for Oxytetracycline

1

Ask your vet for a written prescription

They must provide one on request. Under the CMA Order the fee is capped at £21 from 2027.
2

Fill it at a registered online retailer

The CMA found online pharmacies 50–60% cheaper than practice dispensing on common medicines — typically £200–£300 a year.

Your prescription rights → VMD register of retailers →

Prescription required

Your vet must provide a written prescription on request. You can then purchase from any licensed online retailer.

Clinical information

Cyclosol LA, 200 mg/ml Solution for Injection — SPC Details

Source: VMD Summary of Product Characteristics (SPC). Last updated 27 Mar 2026.

Pigs: For the treatment of respiratory infections caused by oxytetracycline susceptible
organisms such as Pasteurella Multocida.

It is strongly recommended to divide the intramuscular dosages over two or more
injection sites - maximum 15 ml per injection site in cattle over 150 kg body weight and
7 ml in pigs and calves. Injection sites should be alternated.
•
20 mg oxytetracycline per kg bodyweight, if necessary repeat after 72 hours
•not producing milk for human consumption
20 mg oxytetracycline per kg bodyweight, if necessary repeat after 72 hours
•
20 mg oxytetracycline per kg bodyweight as a single injection only
To ensure a correct dosage, body weight should be determined as accurately as
possible.

Do not use in cases of hypersensitivity to the active substance, or to any of the
excipients.
Do not use in animals with an impaired liver and/or kidney function.

Cattle:
Rare
(1 to 10 animals / 10,000
animals treated):
Hypersensitivity reaction including anaphylaxis
a
,
Hepatic toxicosis, Haematologic effects
Very rare
(<1 animal / 10,000 animals
treated, including isolated
reports):
Injection site swelling, injection site reaction (yellow
discolouration), injection site necrosis
b

Undetermined frequency
(cannot be estimated from the
available data)
Photosensitivity
c
,
Decreased milk production
d
Pigs:
Rare
(1 to 10 animals / 10,000
animals treated):
Hepatic toxicosis, Haematologic effects Undetermined frequency
(cannot be estimated from the
available data)
Injection site swelling, injection site reaction (yellow
discolouration), injection site necrosis
b
,
Photosensitivity
c
,
Decreased milk production
d
a
Which may be fatal. In case of a serious anaphylactic reaction in cattle the
administration of
epinephrine, antihistamines and corticosteroids should be considered.

b
Swelling will be visible for several days after injection.
c
When exposed to intensive sunlight, particularly treated animals with poor skin
pigmentation.

d
Small drop in lactating animals for up to 3 days following injection.

Reporting adverse events is important. It allows continuous safety monitoring of a
veterinary medicinal product. Reports should be sent, preferably via a veterinarian, to
either the marketing authorisation holder or its local representative or the national
competent authority via the national reporting system. See the package leaflet for
respective contact details.

None.

Special precautions for safe use in the target species:
For the 250 mL pack, the use of a multidose syringe is recommended. To refill the
syringe, the use of a draw off needle is recommended to avoid excessive broaching of
the stopper.
It is recommended to use the veterinary medicinal product in the early stages of
disease and to evaluate the response to treatment within 72 hours.
Resistance against oxytetracycline may vary. Use of the veterinary medicinal product
should be based on susceptibility testing and taking into account official and local
antimicrobial policies.
Inappropriate use of the veterinary medicinal product may increase the prevalence of
bacteria resistant to oxytetracycline and may decrease the effectiveness of treatment
with tetracyclines due to the potential for cross resistance.
Because oxytetracycline can retard foetal skeletal development and may cause
discoloration and enamel hypoplasia of foetal teeth, the veterinary medicinal product
should be used cautiously in the last half of pregnancy.
Special precautions to be taken by the person administering the veterinary medicinal
product to animals:
People with known hypersensitivity to tetracyclines should avoid contact with the
veterinary medicinal product.
The direct or indirect contact of the user via skin or mucosa should be avoided
because of the risk of sensitisation. Wash hands after use. In case of contact with
eyes or skin, wash immediately with water as irritation may occur.
Laboratory studies in rabbits and rats conducted with the excipient N-methyl
pyrrolidone have shown evidence of foetotoxic effects. Women of childbearing age,
pregnant women or women suspected of being pregnant should use the veterinary
medicinal product with serious caution to avoid accidental self-injection.
Special precautions for the protection of the environment:
Not applicable.
Other precautions:
Not applicable.

Oxytetracycline should not be administered simultaneously with penicillins or
cephalosporins.

Do not freeze. Keep the container in the outer carton.

Cattle : meat and offal : 35 days
milk : 8 days
Pigs : meat and offal : 28 days

This information is sourced from the official Summary of Product Characteristics (SPC) published by the Veterinary Medicines Directorate (VMD). It is provided for informational purposes only and does not replace professional veterinary advice. Always consult your vet before administering any medication.