POM-V Prescription Required

HydroDoxx 500 mg/g Powder for Use in Drinking Water for Chickens and Pigs

Active ingredient: Doxycycline

Form

Powder

Species

Chickens Pigs

Manufacturer

Huvepharma NV

VMD MA No.

30282/4012

What it's used for

Pig (for fattening): treatment and metaphylaxis of clinical respiratory infection caused by strains of Pasteurella multocida The presence of the disease in...

Full indications, dosage and side effects ↓

View official SPC (PDF)

The prescription itself has a price. See what practices near you charge for a consultation and the written prescription fee.

Paying less for Doxycycline + Doxycycline Hy...

1

Ask your vet for a written prescription

They must provide one on request. Under the CMA Order the fee is capped at £21 from 2027.
2

Fill it at a registered online retailer

The CMA found online pharmacies 50–60% cheaper than practice dispensing on common medicines — typically £200–£300 a year.

Your prescription rights → VMD register of retailers →

Prescription required

Your vet must provide a written prescription on request. You can then purchase from any licensed online retailer.

Clinical information

HydroDoxx 500 mg/g Powder for Use in Drinking Water for Chickens and Pigs — SPC Details

Source: VMD Summary of Product Characteristics (SPC). Last updated 27 Mar 2026.

Pig (for fattening): treatment and metaphylaxis of clinical respiratory infection caused
by strains of Pasteurella multocida
The presence of the disease in the group/flock must be established before the
veterinary medicinal product is used.

Chicken (broiler): 20 mg of doxycycline (equivalent to 40 mg of the veterinary
medicinal product)/ kg body weight/day for 3 - 5 days.
Pig (for fattening): 10 mg of doxycycline (equivalent to 20 mg of the veterinary
medicinal product) /kg body weight/day for 5 days.
For the preparation of the medicated water, the body weight of the animals to be
treated and their actual daily water intake should be taken into due account.
Consumption may vary depending on factors like age, state of health, breed,
husbandry system. To ensure a correct dosage, body weight should be determined
as accurately as possible.
Based on the recommended dose and the number and weight of the animals to be
treated, the exact daily concentration of the veterinary medicinal product should be
calculated according to the following formula:
mg veterinary
medicinal product/kg
body weight/day
x
average body weight
(kg) of the animals to
be treated
average daily water intake (l/per animal)
=
mg veterinary
medicinal product
per liter of drinking
water
The intake of medicated water depends on the clinical condition of the animals. In
order to obtain the correct dosage, the concentration of doxycycline may need to be
adjusted accordingly. Do not use at concentrations lower than 0.23 g of powder/l in
drinking water with pH higher or equal to 7.5 to avoid precipitation.
Sufficient access to the system of water supply should be available for the animals to
be treated to ensure adequate water consumption. No other source of drinking water
should be available during the medication period.
The use of suitably calibrated measuring equipment is recommended.
The daily amount is to be added to the drinking water such that all medication will be
consumed in 24 hours. Medicated drinking water should be freshly prepared every 24
hours. It is recommended to prepare a concentrated pre-solution - approximately 100
grams of veterinary medicinal product per liter drinking water - and to dilute this
further to therapeutic concentrations if required. Alternatively, the concentrated
solution can be used in a proportional water medicator.
AN: 00979/2025 & 00982/2025

Do not use in cases of hypersensitivity to the active substance, to other tetracyclines
or to any of the excipients.
Do not use in animals with hepatic disorders.
Do not use in animals with renal disorders.
AN: 00979/2025 & 00982/2025

Chicken (broiler) and pig (for fattening):
Undetermined frequency (cannot be
estimated from the available data)
Allergic reactions*
Photosensitivity*
*If suspected adverse reactions occur, treatment should be discontinued.
Reporting adverse events is important. It allows continuous safety monitoring of a
veterinary medicinal product. Reports should be sent, preferably via a veterinarian, to
either the marketing authorisation holder representative or the national competent
authority via the national reporting system. See the package leaflet for respective
contact details.

The uptake of medication by animals can be altered as a consequence of illness. In
case of insufficient uptake of drinking water, animals should be treated parenterally.

Special precautions for safe use in the target species:
Use of the veterinary medicinal product should be based on identification and
susceptibility testing of the target pathogen(s). If this is not possible, therapy should
be based on epidemiological information and knowledge of susceptibility of the target
pathogens at farm level, or at local/regional level.
Use of the veterinary medicinal product should be in accordance with official, national
and regional antimicrobial policies.
As eradication of the target pathogens may not be achieved, medication should
therefore be combined with good management practices, e.g. good hygiene, proper
ventilation, no overstocking.
Avoid administration in oxidised drinking equipment
Inappropriate use of the veterinary medicinal product may increase the prevalence of
bacteria resistant to doxycyclin and may decrease the effectiveness of treatment with
other tetracyclines due to the potential for cross-resistance.
Do not use at concentrations lower than 0.23 g of powder/l in drinking water with pH
higher or equal to 7.5 to avoid precipitation.
Do not add acid to the medicated drinking water.
Special precautions to be taken by the person administering the veterinary medicinal
product to animals:
People with known hypersensitivity to tetracyclines should avoid contact with the
veterinary medicinal product.
During preparation and administration of the medicated drinking water, skin contact
with the veterinary medicinal product and inhalation of dust particles should be
avoided.
Take measures to avoid producing dust when incorporating the veterinary medicinal
product into water.
Avoid direct contact with skin and eyes when handling the veterinary medicinal
product to prevent sensitisation and contact dermatitis.
Personal protective equipment consisting of impermeable gloves (e.g. rubber or
latex) and an appropriate dust mask (either a disposable half-mask respirator
conforming to European Standard EN149 or a non-disposable respirator to European
Standard EN 140 with a filter to EN 143) should be worn when handling the
veterinary medicinal product.
AN: 00979/2025 & 00982/2025
In case of accidental eye contact or spillage onto skin, rinse the affected area with
large amounts of clean water and if irritation occurs, seek medical advice
immediately and show the package leaflet or the label to the physician.
Wash hands and contaminated skin immediately after handling the veterinary
medicinal product.
If you develop symptoms following exposure such as skin rash, you should seek
medical advice and show the package leaflet or the label to the physician. Swelling of
the face, lips or eyes, or difficulty with breathing are more serious symptoms and
require urgent medical attention.
Do not smoke, eat or drink while handling the veterinary medicinal product.
Special precautions for the protection of the environment:
Not applicable.

Do not administer together with bactericidal antibiotics (penicillins, aminoglycosides,
etc.).
Absorption of doxycycline can be decreased in the presence of high quantities of
calcium, iron, magnesium or aluminium in the diet. Do not administer together with
antacids, kaolin and iron preparations.
It is advised that the interval between the administration of other products containing
polyvalent cations should be 1-2 hours because they limit the absorption of
tetracyclines.
AN: 00979/2025 & 00982/2025
Doxycycline increases the action of anticoagulants.

This veterinary medicinal product does not require any special storage conditions.
AN: 00979/2025 & 00982/2025

Pig (for fattening):
Meat and offal: 6 days.
Chicken (broiler):
Meat and offal: 6 days.
Not for use in birds producing eggs for human consumption.
Do not use within 4 weeks before the start of the laying period.

This information is sourced from the official Summary of Product Characteristics (SPC) published by the Veterinary Medicines Directorate (VMD). It is provided for informational purposes only and does not replace professional veterinary advice. Always consult your vet before administering any medication.