Fiprotec Combo 402 mg/ 361.8 mg Spot-on Solution for Extra Large Dogs

Bathing/immersion in water within 2 days after application of the veterinary medicinal
product and more frequent bathing than once a week should be avoided, as no study
has been performed to investigate how this affects the efficacy of the veterinary
medicinal product. Emollient shampoos can be used prior to treatment, but reduce
the duration of protection against fleas to approximately 5 weeks when used weekly
after application of the veterinary medicinal product. Weekly bathing with a 2%
chlorhexidine medicated shampoo did not affect efficacy against fleas during a 6
weeks long study.
There may be an attachment of a few ticks. For this reason, a transmission of
infectious diseases cannot be completely excluded if conditions are unfavourable.
When treating infestations of parasites, all in-contact animals should be treated with
an appropriate veterinary medicinal product at the same time. Fleas from pets often
infest the animal's basket, bedding and regular resting areas such as carpets and
soft furnishings which should be treated, in case of massive infestation and at the
beginning of the control measures, with a suitable insecticide and vacuumed
regularly.

Special precautions for safe use in the target species:
Avoid contact with the animal's eyes.
It is important to make sure that the veterinary medicinal product is applied to an area
where the animal cannot lick it off and to make sure that animals do not lick each
other following treatment.
Do not overdose.
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Special precautions to be taken by the person administering the veterinary medicinal
product to animals:
This veterinary medicinal product can cause mucous membrane, skin and eye
irritation. Therefore, contact of the veterinary medicinal product with mouth, skin and
eyes should be avoided.
People with a known hypersensitivity (allergy) to fipronil, S-methoprene, insecticides
or alcohol should avoid contact with the veterinary medicinal product. Avoid contents
coming into contact with the fingers. If this occurs, wash hands with soap and water.
After accidental ocular exposure the eye should be rinsed carefully in clean water.
If the veterinary medicinal product is accidentally swallowed, seek medical advice
immediately and show the package leaflet to the physician.
Wash hands after use.
Do not smoke, drink or eat during application.
Treated animals should not be handled until the application site is dry, and children
should not be allowed to play with treated animals until the application site is dry. It is
therefore recommended that animals are not treated during the day, but should be
treated during the early evening, and that recently treated animals are not allowed to
sleep with owners, especially children.
Keep pipettes in original packaging until ready to use.
Special precautions for the protection of the environment:
Dogs should not be allowed to swim in watercourses for 2 days after application (see
section 5.5).