POM-V Prescription Required

Doxylin, 433 mg/g, Powder for Use in Drinking Water for Chickens and Turkeys

Active ingredient: Doxycycline

Form

Powder

Species

Chickens Turkeys

Manufacturer

Dopharma Research B.V.

VMD MA No.

28365/4006

What it's used for

Treatment of the following conditions caused by bacteria sensitive to doxycycline: Dogs: Rhinitis caused by Bordetella bronchiseptica and Pasteurella spp.;...

Full indications, dosage and side effects ↓

View official SPC (PDF)

The prescription itself has a price. See what practices near you charge for a consultation and the written prescription fee.

Paying less for Doxycycline

1

Ask your vet for a written prescription

They must provide one on request. Under the CMA Order the fee is capped at £21 from 2027.
2

Fill it at a registered online retailer

The CMA found online pharmacies 50–60% cheaper than practice dispensing on common medicines — typically £200–£300 a year.

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Prescription required

Your vet must provide a written prescription on request. You can then purchase from any licensed online retailer.

Clinical information

Doxylin, 433 mg/g, Powder for Use in Drinking Water for Chickens and Turkeys — SPC Details

Source: VMD Summary of Product Characteristics (SPC). Last updated 27 Mar 2026.

Treatment of the following conditions caused by bacteria sensitive to doxycycline:
Dogs:
Rhinitis caused by Bordetella bronchiseptica and Pasteurella spp.;
Bronchopneumonia caused by Bordetella spp. and Pasteurella spp.;
Interstitial nephritis caused by Leptospira spp.;
Cats:
Respiratory infections caused by Bordetella bronchiseptica,
Pasteurella spp.

To ensure a correct dosage, body weight should be determined as accurately as possible.
The intake of medicated water depends on the clinical conditions of the animals. In order
to obtain the correct dosage, the concentration of doxycycline may need to be adjusted
accordingly.
The use of suitably calibrated measuring equipment is recommended if part packs are
used
Dosage:
In chickens
20 mg doxycycline per kg of body weight daily (equivalent to 46 mg veterinary medicinal
product per kg of body weight), administered in the drinking water for 5 consecutive days.
In turkeys
25 mg doxycycline per kg of body weight daily (equivalent to 58 mg veterinary medicinal
product per kg of body weight), administered in the drinking water for 5 consecutive days.
Administration:
Based on the recommended dose, and the number and weight of the animals to be
treated, the exact daily amount of veterinary medicinal product should be calculated
according to the following formula:
..... mg veterinary
medicinal product per kg
body weight per day
X
mean body
weight (kg) of
animals to be
treated
mean daily water consumption (litre per animal)
=.... mg veterinary
medicinal product per
litre of drinking water
The daily amount is to be added to the drinking water such that all medication will be
consumed in 24 hours. Medicated drinking water should be freshly prepared every 24
hours. It is recommended to prepare a concentrated pre-solution - not exceeding 100
grams veterinary medicinal product per litre drinking water - and to dilute this further to
AN: 01456/2024 & 01458/2024
therapeutic concentrations, if required. Alternatively; the concentrated solution can be
used in a proportional water medicator.
It should be ensured that all animals intended for treatment should have free access to the
drinking facilities. At the end of treatment, the watering equipment should be cleaned
adequately to avoid the intake of remaining quantities in sub-therapeutic doses. The
medicated water should be the only source of drinking water, throughout the treatment
period. The medicated water must not be made or stored in a metal container. Solubility of
the veterinary medicinal product is pH dependent and it will precipitate if it is mixed in an
alkaline solution. In order to ensure a complete and permanent dissolution of the
veterinary medicinal product in each water quality, a minimum concentration is required.
The minimum concentration in drinking water is 200 mg veterinary medicinal product per
litre. Animals requiring a lower concentration should not be treated with the veterinary
medicinal product.

Do not use in cases of hypersensitivity to the active substance or to any of the excipients.
Do not use when tetracycline resistance has been detected in the herd/flock due to the
potential for cross resistance.
Do not use in animals with hepatic dysfunction.

Chickens (broilers, broiler breeders) and turkeys (broilers, breeders):
Rare
(1 to 10 animals / 10,000 animals treated):
Allergic reaction
Photosensitivity
If suspected adverse reactions occur, treatment should be discontinued.
Reporting adverse events is important. It allows continuous safety monitoring of a
veterinary medicinal product. Reports should be sent, preferably via a veterinarian, to
either the marketing authorisation holder or the national competent authority via the
national reporting system. See the package leaflet for respective contact details.
AN: 01456/2024 & 01458/2024

The intake of medication by animals can be altered as a consequence of illness. In case of
insufficient intake of drinking water, animals should be treated parenterally.
AN: 01456/2024 & 01458/2024

Special precautions for safe use in the target species:
Due to variability (time, geographical) in susceptibility of bacteria for doxycycline,
bacteriological sampling and susceptibility testing of micro-organisms from diseased
animals on farm are highly recommended.
Use of the veterinary medicinal product deviating from the instructions given in the SPC
may increase the prevalence of bacteria resistant to doxycycline and may decrease
effectiveness of treatment with tetracyclines due to the potential for cross resistance.
Use of the veterinary medicinal product should take into account official and local
antimicrobial policies.
Avoid administration in oxidized drinking equipment.
As eradication of the target pathogens may not be achieved, medication should therefore
be combined with good management practices, e.g. good hygiene, proper ventilation, no
overstocking.
Special precautions to be taken by the person administering the veterinary medicinal
product to animals:
During preparation and administration direct contact of the veterinary medicinal product
with the skin, eyes and mucous membranes and inhalation of dust particles should be
avoided.
People with known hypersensitivity to tetracyclines should avoid contact with the
veterinary medicinal product.
Personal protective equipment consisting of protective gloves (e.g. rubber or latex),
glasses and an appropriate dust mask (e.g. disposable half-mask respirator conforming to
European Standard EN149 or a non-disposable respirator to European Standard EN140
with a filter to EN143) should be worn when handling the veterinary medicinal product.
Wash exposed skin after preparation of medicated drinking water.
In case of accidental eye contact, rinse with plenty of fresh water. Do not smoke, eat or
drink when handling the veterinary medicinal product.
In case of accidental ingestion, seek medical advice immediately and show the package
leaflet or the label to the physician. Inflammation of the face, lips or eyes or respiratory
difficulties are the most serious signs which require urgent medical attention.
Special precautions for the protection of the environment:
Not applicable.

Do not administer concurrently with feed overloaded with polyvalent cations such as Ca
2+
,
Mg
2+
, Zn
2+
and Fe
3+
because the formation of doxycycline complexes with these cations is
possible. Do not administer together with antacids, kaolin and iron preparations as
tetracyclines are bacteriostatic antimicrobials, do not administer in conjunction with
bactericidal antibiotics like beta-lactams. It is advised that the interval between
administration of other veterinary medicinal products containing polyvalent cations should
be 1-2 hours because they limit the absorption of tetracycline.
Doxycycline increases the action of anticoagulants.

Store below 25 C
Keep the container tightly closed in order to protect from light.
Medicated drinking water should be protected from light.

Meat and offal:
Chickens: 5 days.
Turkeys: 12 days.
Not for use in birds producing eggs for human consumption.
4.

This information is sourced from the official Summary of Product Characteristics (SPC) published by the Veterinary Medicines Directorate (VMD). It is provided for informational purposes only and does not replace professional veterinary advice. Always consult your vet before administering any medication.