Cydectin 0.5% w/v Pour-on for Cattle

None.

Special precautions for safe use in the target species:
For topical application only.
To avoid secondary reactions due to the death of Hypoderma larvae in the oesophagus
or the spine, it is recommended to administer the veterinary medicinal product at the end
of the period of fly activity and before the larvae reach their resting sites: consult the
veterinarian to know the correct treatment period.
Special precautions to be taken by the person administering the veterinary medicinal
product to animals
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medicinal product.
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immediately.
Special precautions for the protection of the environment:
Moxidectin fulfils the criteria for a (very) persistent, bioaccumulative and toxic (PBT)
substance; therefore, exposure of the environment to moxidectin must be limited to the
extent possible. Treatments should be administered only when necessary and should be
based on faecal egg counts or evaluation of the risk of infestation at the animal and/or
herd level.
Like other macrocyclic lactones, moxidectin has the potential to adversely affect non-
target organisms:
•
temporarily reduce the abundance of dung feeding organisms. Following treatment of
cattle with the veterinary medicinal product, levels of moxidectin that are potentially
toxic to dung fly species may be excreted over a period more than 2 weeks and may
decrease dung fly abundance during that period. It has been established in laboratory
tests that moxidectin may temporarily affect dung beetle reproduction; however, field
studies indicate no-long term effects. Nevertheless, in case of repeated treatments
with moxidectin (as with veterinary medicinal products of the same anthelmintic class)
it is advisable not to treat animals every time on the same pasture to allow dung fauna
populations to recover.
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medicinal product should be used only according to the label instructions. Based on
the excretion profile of moxidectin when administered as the pour-on formulation,
treated animals should not have access to watercourses during the first week after
treatment.