POM-V Prescription Required

Cyclix Porcine 87.5 Microgram/ml Solution for Injection

Active ingredient: Cloprostenol

Form

Injection

Species

Pigs

Manufacturer

Virbac

VMD MA No.

05653/5039

What it's used for

Induction or synchronisation of farrowing (within 16 to 34 hours) pregnancy onwards (day 1 of pregnancy is the last day of natural or artificial inseminati...

Full indications, dosage and side effects ↓

View official SPC (PDF)

The prescription itself has a price. See what practices near you charge for a consultation and the written prescription fee.

Paying less for Cloprostenol

1

Ask your vet for a written prescription

They must provide one on request. Under the CMA Order the fee is capped at £21 from 2027.
2

Fill it at a registered online retailer

The CMA found online pharmacies 50–60% cheaper than practice dispensing on common medicines — typically £200–£300 a year.

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Prescription required

Your vet must provide a written prescription on request. You can then purchase from any licensed online retailer.

Clinical information

Cyclix Porcine 87.5 Microgram/ml Solution for Injection — SPC Details

Source: VMD Summary of Product Characteristics (SPC). Last updated 26 Mar 2026.

Induction or synchronisation of farrowing (within 16 to 34 hours)
pregnancy onwards (day 1 of pregnancy is the last day of natural or artificial insemination).

2 ml corresponding to 0.175 mg cloprostenol/animal.
For intramuscular injection.
Single administration.
Deep intramuscular injection with a needle at least 4 cm long is recommended.

Do not use in pregnant animals, for which induction of abortion or parturition is not
intended. Do not use in the case of distocic parturition due to abnormal position of the
foetus, mechanical obstruction, etc….
Do not use in animals with spastic diseases of the respiratory or gastrointestinal tract.

Revised : July 2023
Divergence from NI MA following AN : 00722/2022

Behavioural changes seen after treatment for induction of farrowing are similar to those
changes associated with natural farrowing and usually cease within one hour.
Anaerobic infection may occur if anaerobic bacteria penetrate the tissue at injection site, in
particular following intramuscular injection.

None

Special precautions for use in animals
The product should only be used on farms where accurate insemination records are kept.
Do not use before day 113 of pregnancy, as this may lead to increased mortality and
reduced vitality of new-born piglets. Induction of labour before the 111
th
day of gestation
may cause mortality in piglets and an increase in the number of sows that require manual
assistance.
As with parenteral administration of any substance, basic aseptic rules should be
observed. The injection site must be thoroughly cleaned and disinfected in order to reduce
the risk of infection with anaerobic bacteria.
Special precautions to be taken by the person administering the veterinary
medicinal product to animals
People with known hypersensitivity to benzyl alcohol should avoid contact with the
product.
Do not eat, drink or smoke while handling the product. Direct contact with skin or mucous
membranes of the user should be avoided. Prostaglandins of the F2α type may be
absorbed through the skin and may cause bronchospasm or miscarriage. The product
must be handled carefully to avoid ACCIDENTAL SELF-INJECTION OR SKIN CONTACT.
Pregnant women, women in childbearing age, asthmatics and persons with other
respiratory tract diseases should exercise caution when handling cloprostenol. Those
persons should wear rubber (or plastic) gloves during administration of the product.
Accidental spillage on the skin should be washed immediately with soap and water.
In case of accidental self-injection, seek medical advice immediately and show the
package insert or the label to the physician.

The activity of other oxytocic agents can be increased after the administration of
cloprostenol.
Do not use in animals being treated with non-steroidal anti-inflammatories, as the
synthesis of endogenous prostaglandins is inhibited.

Keep the vial in the outer carton
Protect from light.

Pig: Meat & offal: 2 days
5.

This information is sourced from the official Summary of Product Characteristics (SPC) published by the Veterinary Medicines Directorate (VMD). It is provided for informational purposes only and does not replace professional veterinary advice. Always consult your vet before administering any medication.