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AVM-GSL Over the Counter Companion Animal

Bob Martin Clear Plus 50 mg/ 60 mg Spot-on Solution for Cats and Ferrets

Active ingredients: (S)-Methoprene, Fipronil

Form

Spot-on

Species

Cats Ferrets

Manufacturer

Pets Choice Limited

VMD MA No.

52797/5018

What it's used for

In cats: -To be used against infestations with fleas, alone or in association with ticks and/or biting lice. -Elimination of fleas (Ctenocephalides spp.)....

Full indications, dosage and side effects ↓
View official SPC (PDF)

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Paying less for (S)-Methoprene + Fipronil

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Clinical information

Bob Martin Clear Plus 50 mg/ 60 mg Spot-on Solution for Cats and Ferrets — SPC Details

Source: VMD Summary of Product Characteristics (SPC). Last updated 26 Mar 2026.

In cats:
-To be used against infestations with fleas, alone or in association with ticks and/or
biting lice.
-Elimination of fleas (Ctenocephalides spp.). Insecticidal efficacy against new
infestations with adult fleas persists for 4 weeks. Prevention of the multiplication of
fleas by inhibiting the development of eggs (ovicidal activity), larvae and pupae
(larvicidal activity) originating from eggs laid by adult fleas for six weeks after
application.
-Elimination of ticks (Ixodes , ,
Rhipicephalus ) The product has a persistent acaricidal efficacy for up to
2 weeks against ticks (based on experimental data).
-Elimination of biting lice (Felicola subrostratus).
In ferrets:

Revised: October 2025
MA split from NI MA following AN: 02133/2025
-To be used against infestations with fleas, alone or in association with ticks.
- Elimination of fleas (Ctenocephalides spp.). Insecticidal efficacy against new
infestations with adult fleas persists for 4 weeks. Prevention of the multiplication of
fleas by inhibiting the development of eggs (ovicidal activity), larvae and pupae
(larvicidal activity) originating from eggs laid by adult fleas.
- Elimination of ticks (Ixodes ,). The product has a persistent acaricidal efficacy
for 4 weeks against ticks (based on experimental data).
One pipette of 0.5 ml per cat, corresponding to a minimum recommended dose of
5 mg/kg for fipronil and 6 mg/kg for (S)-methoprene, by topical application to the skin.
In the absence of safety studies, the minimum treatment interval is 4 weeks.
One pipette of 0.5 mL per ferret corresponding to a dose of 50 mg for fipronil and 60
mg for (S)-methoprene per ferret, by topical application to the skin.
The minimum treatment interval is 4 weeks.
Method of administration:

Thermoformed pipettes:
1. Bob Martin Clear Plus must be applied at 2 points, at the base of the back of
the cat’s head and between the shoulder blades. If the pet is wearing a collar
remove it first so that it does not restrict application.
2. Remove a single pipette from the pack. To open, hold the pipette upright and
snap off the tip.
3. Part your pet’s coat until the skin is visible. Place the tip of the pipette directly
against the skin and squeeze gently. Apply approximately half of the pipette at
one point and half at the second point. Avoid applying onto the fur and do not
rub into the skin as this will reduce the product’s performance.

Revised: October 2025
MA split from NI MA following AN: 02133/2025
Polypropylene pipettes
1. Bob Martin Clear Plus must be applied at 2 points – at the base of the back
of the pet’s head and between the shoulder blades. If the pet is wearing a
collar remove it first so that it does not restrict application.
2. Remove a single pipette from the pack. Hold the pipette upright and snap
off the top section of the cap opening the pipette.
3. Part your pet’s coat until the skin is visible. Place the tip of the pipette
directly against the skin and squeeze gently. Apply approximately half of the
pipette at one point and half at the second point. Avoid applying onto the fur
and do not rub into the skin as this will reduce the product’s performance.
Apply to an area where the animal cannot lick it off and do not allow pets to lick
each other after treatment.
Temporary changes to the coat (clumped/greasy hair) may be noted at the
application site.
In the absence of available data, the product should not be used on kittens less than
8 weeks old and/or weighing less than 1 kg. The product should not be used on
ferrets less than 6 months old.
Do not use on sick (e.g. systemic diseases, fever) or convalescent animals.
Do not use in rabbits, as adverse reactions with even mortality could occur.
absence of studies, the use of the product is not recommended in non-target species.
Do not use in known cases of hypersensitivity to the active substance or to any of the
excipients.
Do not overdose.
Cats:
Among the very rare suspected adverse reactions, transient skin reactions on the
application site (scaling, local hair loss, itching, redness) and general itching or hair
loss have been reported after use. Excessive salivation, reversible nervous signs
(increased sensitivity to stimulation, depression, other nervous signs) or vomiting
have also been observed after use.
The frequency of adverse reactions is defined using the following convention:
- very common (more than 1 in 10 animals treated displaying adverse reaction(s))
- common (more than 1 but less than 10 animals in 100 animals treated)
- uncommon (more than 1 but less than 10 animals in 1,000 animals treated)
- rare (more than 1 but less than 10 animals in 10,000 animals treated)
- very rare (less than 1 animal in 10,000 animals treated, including isolated reports).
If licking occurs, a brief period of excessive salivation may be observed due mainly to
the nature of the carrier .
Avoid the contact with the animal’s eyes.
When treating infestations of parasites, all in-contact animals should be treated with
an appropriate product at the same time.

Special precautions for use in animals
It is important to make sure that the product is applied to an area where the animal
cannot lick it off and to make sure that animals do not lick each other following
treatment.
No data on the effect of bathing/shampooing on the efficacy of the product in cats
and ferrets are available. However, based on information available for dogs
shampooed as from 2 days after application of the product, it is not recommended to
bath animals within 2 days after application of the product.
There may be an attachment of single ticks. For this reason a transmission of
infectious diseases cannot be completely excluded if conditions are unfavourable.
Fleas from pets often infest the animal's basket, bedding and regular resting areas
such as carpets and soft furnishings which should be treated, in case of massive
infestation and at the beginning of the control measures, with a suitable insecticide
and vacuumed regularly.
The potential toxicity of the product for kittens of less than 8 weeks of age in contact
with a treated queen is not documented. Special care should be taken in this case.
Animals should be weighed accurately prior to treatment.

Revised: October 2025
MA split from NI MA following AN: 02133/2025
Special precautions to be taken by the person administering the veterinary medicinal
product to animals
Keep pipettes in original packaging until ready to use.
This product can cause mucous membrane, skin and eye irritation. Avoid contents
coming into contact with your mouth, skin and eyes.
If skin contact does occur, wash it off quickly and thoroughly with soap and water.
In case of accidental eye contact, immediately and thoroughly flush the eyes with
clean water.
If the product is accidentally swallowed, or irritation of the eye persists, seek medical
advice and show the packaging to the physician.
Do not smoke, drink or eat during application.
People with a known hypersensitivity (allergy) to insecticides or alcohol should avoid
contact with the product.
Treated animals should not be handled until the application site is dry; in particular,
children should not be allowed to play with treated animals until the application site is
dry. It is therefore recommended that animals are not treated during the day, but
during the early evening.
Recently treated animals should not be allowed to sleep with owners, especially
children.
Wash hands thoroughly after use with soap and water.
Do not use simultaneously with other flea products which are applied directly on to
the animal.
Do not store above 25C.
Store in the original package.
Store in a dry place.

Revised: October 2025
MA split from NI MA following AN: 02133/2025
Not applicable.
5.

This information is sourced from the official Summary of Product Characteristics (SPC) published by the Veterinary Medicines Directorate (VMD). It is provided for informational purposes only and does not replace professional veterinary advice. Always consult your vet before administering any medication.

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