POM-V Prescription Required

Avishield ND, Lyophilisate for Oculonasal Suspension/Use in Drinking Water for Chickens and Turkeys

Active ingredient: Newcastle disease virus

Form

Lyophilisate

Species

Chickens Turkeys

Manufacturer

IZO S.r.l a socio unico

VMD MA No.

61812/3000

What it's used for

Onset of immunity: 21 days post vaccination. Duration of immunity: 35 days post vaccination. For active immunisation of turkeys to prevent mortality and cl...

Full indications, dosage and side effects ↓

View official SPC (PDF)

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Paying less for Newcastle disease virus

1

Ask your vet for a written prescription

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2

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Prescription required

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Clinical information

Avishield ND, Lyophilisate for Oculonasal Suspension/Use in Drinking Water for Chickens and Turkeys — SPC Details

Source: VMD Summary of Product Characteristics (SPC). Last updated 27 Mar 2026.

Onset of immunity: 21 days post vaccination.
Duration of immunity: 35 days post vaccination.
For active immunisation of turkeys to prevent mortality and clinical signs due to infection
with
Newcastle disease virus.
Onset of immunity: 21 days post vaccination.
Duration of immunity has not been established.

can be administered in drinking water at the time when birds are drinking continuously
from the drinking system.
Turkeys: 1 dose by coarse spray, oculonasal use or in drinking water use from the age
of 14 days.
Method of application depends on the epizootiological situation, age, category and
number of animals. The veterinarian should determine the optimum vaccination
schedule according to the local situation taking into account the information provided in
section 3.4.
It is extremely important that all birds receive the full dose of vaccine. Details presented
below should be strictly followed to achieve this.
After reconstitution the vaccine appears as a clear to slightly opalescent suspension.
If prolonged immunity is required, chickens can be revaccinated after 35 days.
Revaccination in turkeys has not been investigated.
1. Oculonasal use
Reconstitute 1 000 doses of the vaccine in 100 ml distilled water.
A dose of reconstituted vaccine is 0.1 ml, i.e. two drops, irrespective of poultry age,
weight and type. Instil one drop into an eye and one drop into the nostril.
2. In drinking water use
Reconstitute the vaccine in cool and clean water without traces of chlorine, other
disinfectants or impurities in a number of doses corresponding to the number of birds to
be vaccinated.
The vaccine should be reconstituted immediately before use.
The volume of water for reconstitution depends on the age of the birds, the breed, the
management practice and weather conditions.
In order to determine the quantity of water in which vaccine will be reconstituted
for the vaccination of chickens in a younger age category (until the third week of life),
the following guideline applies:
-
thousand chickens in the 7th day of life = 1 x 7 = 7 L)
It is important to reconstitute the vaccine in the amount of water which will be drunk
within 1.5 - 2.5 hours (taking into account the different types of drinking systems for
poultry).
In order to make the birds thirsty, withdraw the supply of drinking water up to 2 hours
prior to vaccination (depending on the air temperature).
Always make sure that there is food available when vaccinating. Birds will not drink if
they have no food to eat. The drinking system should be clean, without traces of
chlorine, other disinfectants or impurities.
3. Coarse spray
It is recommended to reconstitute 1 000 doses of the vaccine in 150 - 300 ml of distilled
water. The number of doses to be used corresponds to the number of birds in the flock.
The volume of water for reconstitution should be sufficient to ensure an even distribution
when sprayed onto the birds, and will vary according to the age of the birds being
vaccinated and the management system.
The reconstituted vaccine suspension should be spread evenly over the correct number
of chickens, at a distance of 30 – 40 cm using a coarse spray, preferably when the
chickens are sitting together in dim light. The spray apparatus should be free from
sediments, corrosion and traces of disinfectants and ideally should be used for
vaccination purposes only. During and after vaccination ventilation should be switched
off in order to avoid turbulences.

None.

Chickens:
Very common
(>1 animal / 10 animals treated):
Respiratory signs
a
a
After oculonasal use. These symptoms could last at least two weeks.
Reporting adverse events is important. It allows continuous safety monitoring of a
veterinary medicinal product. Reports should be sent, preferably via a veterinarian, to
either the marketing authorisation holder or the national competent authority via the
national reporting system. See the package leaflet for respective contact details.

Vaccinate healthy animals only.
Maternally Derived Antibodies (MDA) can interfere with the development of active
immunity.
Where it is likely, for example, that a recent field infection or vaccination of the parent
flock has stimulated a high antibody titre and consequently a high level of MDA the
vaccination programme should be planned accordingly.
It has been shown in laboratory studies that MDA interfere with vaccination by the spray
and oral route and can result in up to 55% unprotected birds 3 - 4 weeks post
vaccination. Better protection in these studies was seen by oculonasal delivery but the
onset of immunity was delayed by a week.
Influence of MDA on vaccination in turkeys has not been investigated.

Special precautions for safe use in the target species:
All birds in the flock should be vaccinated at the same time.
The vaccine strain can spread to susceptible, unvaccinated birds for at least 10 days
following vaccination. The spread does not induce clinical signs.
Vaccine virus can disseminate to the trachea, spleen, kidneys, lung, caecal tonsils,
duodenum and brains of chickens without inducing pathological changes to these
organs.
Special precautions to be taken by the person administering the veterinary medicinal
product to animals:
Care should be taken when handling and administering the vaccine.
Newcastle disease virus can cause a mild transient conjunctivitis in the person
administering the vaccine. Personal protective equipment consisting of a mask and eye
protection should be worn when handling the veterinary medicinal product. Wash and
disinfect hands after administration of the vaccine.
Special precautions for the protection of the environment:
Not applicable.

No information is available on the safety and efficacy of this vaccine when used with
any other veterinary medicinal product. A decision to use this vaccine before or after
any other veterinary medicinal product therefore needs to be made on a case by case
basis.

Store in a refrigerator (2 °C – 8 °C).
Protect from light.

Zero days.

This information is sourced from the official Summary of Product Characteristics (SPC) published by the Veterinary Medicines Directorate (VMD). It is provided for informational purposes only and does not replace professional veterinary advice. Always consult your vet before administering any medication.