Avishield ND B1, Lyophilisate for Oculonasal Suspension/Use in Drinking Water for Chickens

In drinking water use: from 7 days of age.
One dose per chicken.

The method of application depends on the epizootiological situation, age category
and number of animals.
After reconstitution the vaccine appears as a clear to slightly opalescent suspension.
1. Eye/nasal drop
Reconstitute 1 000 doses of the vaccine in 100 ml distilled water.
A dose of reconstituted vaccine is 0.1 ml, i.e. two drops, irrespective of poultry age,
weight and type. Instil one drop into an eye and one drop into at nostril.
For chickens aged from 1 to 14 days of smaller breeds, 4 drops of 25 l should be
used. Administer one drop in each eye (0.05 ml altogether) and then one drop in
each nostril (0.05 ml altogether).
2. In drinking water use
Reconstitute the vaccine in cool and clean water without traces of chlorine, other
disinfectants or impurities in a number of doses corresponding to the number of birds
to be vaccinated. Where the number of birds is between the standard dosages, the
next higher dosage should be used.
The vaccine should be reconstituted immediately before use.
Measure the correct volume of water for the number of birds to be vaccinated. The
volume of water depends on the age of the birds, breed, management practice and
weather conditions. In order to determine the quantity of water in which vaccine will
be reconstituted, measure the volume of water consumed within a two hours period
one day before vaccination.
The vaccine should be reconstituted in the amount of water which will be drunk within
1.5 to 2.0 hours (taking into account the different types of drinking systems for
poultry).
As a guideline for younger chickens (until 3rd week of life), apply the reconstituted
vaccine to cold and fresh water at the rate of 1 000 doses of vaccine to 1 litre of
water per day of age for 1 000 chickens, e.g. 7 litres would be needed for 1 000,
chickens of 7 days old.
In order to make the birds thirsty, withdraw the supply of drinking water up to 2 hours
prior to vaccination (drinking behaviour of the birds varies, depending on the air
temperature, type of birds, breed, management, weather conditions).
The drinking system should work properly and should be clean, without traces of
chlorine, other disinfectants or impurities.
If needed, turn the lights down low when the water supply is turned off. After the
vaccine is added to the drinking water, increase the light. Increased light intensity will
stimulate the birds to look for food and water.
Once the vaccine has been consumed, resume management practices as normal.
This approach to vaccination will ensure a more even vaccination of the flock and will
be less stressful to the birds. Performance should therefore be less adversely
affected.
3. Coarse spray
It is recommended to reconstitue 1 000 doses of the vaccine in 150 - 300 ml of
distilled water. The number of doses reconstituted corresponds to the number of
birds in a flock.
The volume of water for reconstitution should be sufficient to ensure an even
distribution when sprayed onto the birds, and will vary according to the age of the
birds being vaccinated and the management system. The reconstituted vaccine
suspension should be spread evenly over the correct number of chickens, at a
distance of 30 – 40 cm using a coarse spray (targeted average droplet size of 150 -
170 microns), preferably when the chickens are sitting together in dim light.