POM-V Prescription Required

AviPro ND C131 Lyophilisate for Suspension for Chickens and Turkeys

Active ingredient: Newcastle disease virus

Form

Lyophilisate

Species

Chickens Turkeys

Manufacturer

Elanco GmbH

VMD MA No.

52127/3034

What it's used for

Chickens: Onset of immunity: 3 weeks after vaccination (7 days in seronegative chickens when vaccinated at 14 days of age). Duration of immunity: 8 weeks a...

Full indications, dosage and side effects ↓

View official SPC (PDF)

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Paying less for Newcastle disease virus

1

Ask your vet for a written prescription

They must provide one on request. Under the CMA Order the fee is capped at £21 from 2027.
2

Fill it at a registered online retailer

The CMA found online pharmacies 50–60% cheaper than practice dispensing on common medicines — typically £200–£300 a year.

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Prescription required

Your vet must provide a written prescription on request. You can then purchase from any licensed online retailer.

Clinical information

AviPro ND C131 Lyophilisate for Suspension for Chickens and Turkeys — SPC Details

Source: VMD Summary of Product Characteristics (SPC). Last updated 27 Mar 2026.

Chickens:
Onset of immunity: 3 weeks after vaccination (7 days in seronegative chickens
when vaccinated at 14 days of age).
Duration of immunity: 8 weeks after vaccination
Turkeys:
Onset of immunity: 2 weeks after vaccination
Duration of immunity: 8 weeks after vaccination
AN: 00325/2025Page 2 of 7

•
•
•
•
a) Ocular use (chickens)
The equipment used for eye drop application should be clean, free of detergents
and disinfectants and should be used for vaccination purposes only.
For preparation of the vaccine use 34 ml of boiled and cooled drinking water per
1000 doses of vaccine.
Administer 1 droplet (corresponding to approximately 34 µl) into one eye of each
chicken to be vaccinated by use of a pipette or dropper.
b) Nebulisation (chickens)
The amount of drinking water to be used for nebulisation depends on local and
husbandry conditions.
After removing the stopper under water 1000 doses of vaccine are diluted as
follows:
•
th
week of life
•
th
week of life.
The chickens are sprayed uniformly with a distance of 30 – 40 cm.
During and after vaccination ventilation should be switched off in order to avoid
turbulences.
For primary vaccination during the 1
st
weeks of life a coarse spray having a droplet
size of 100 µm and more should be used to avoid penetration into the lower parts of
the respiratory tract and increased vaccination reactions.
c) In drinking water use (chickens and turkeys)
1. all equipment used for vaccination (tubes, drinkers etc.) are carefully cleaned
and are free of detergents and disinfectants.
2. Estimate the amount of water according to the number of birds to be
vaccinated (see 5.) Only cold clean water of drinking water quality should be
used.
The addition of skimmed milk powder (2 – 4 g/l water) or skimmed milk
(20 – 40 ml/l water) may positively influence the stability of the vaccine.
Skimmed milk powder or skimmed milk must be carefully mixed with the
water before dilution of the vaccine.
3. Remove aluminium-cap. Open the stopper of vaccine bottle under water and
dilute the contents completely.
4. For easy handling the vaccine should be prepared in a small container (about
1 litre). Rinse the vial carefully and empty it completely. The vaccine
suspension is then diluted in a larger vessel (5 – 10 l) and mixed well again.
The complete content of the vaccine vials should be used for one flock or
drinking water system only. Splitting of the diluted vaccine may lead to
dosage errors.
AN: 00325/2025Page 5 of 7
5. To the vaccine suspension fresh cold water is added to a final volume that will
be consumed by the birds within 1 – 2 hours. In case of doubt the uptake of
water should be established the day before vaccination.
6. Drinker lines still filled with water must be drained before application of the
vaccine suspension. The vaccine should be consumed within 2 hours. Since
drinking behaviour of birds is varying it may be necessary to withdraw the
drinking water for 2-3 hours before vaccination to ensure that all birds will
drink during the vaccination phase. Every bird should receive an adequate
dose of the vaccine.

None.

Chickens:
Common
(1 to 10 animals / 100 animals
treated):
Respiratory tract disorders* like cough and
sneezing
*3 – 15 days after vaccination. This does not influence the performance of the birds.
AN: 00325/2025Page 3 of 7
Severity and duration of adverse reactions are dependent on the (maternal) immune
status as well as the general health condition of the chickens at the time point of
vaccination.
Turkeys:
None.
Reporting adverse events is important. It allows continuous safety monitoring of a
veterinary medicinal product. Reports should be sent, preferably via a veterinarian,
to either the marketing authorisation holder or the national competent authority via
the national reporting system. See the package leaflet for respective contact details.

Vaccinate healthy animals only.
See also section 3.7
Maternally derived antibodies (MDA) may interfere with the development of a
protective immune response following vaccination.

Special precautions for safe use in the target species:
Chickens:
The vaccine virus is excreted with faeces up to 12 days and may spread to
susceptible animals by contact infection. However, ND negative contact animals do
not show sero-conversion until 15 days after contact.
Turkeys:
The vaccine virus is excreted for less than 14 days after vaccination.
The vaccine virus may spread to susceptible non-vaccinated turkeys without
inducing any clinical symptoms.
Transmission of the vaccine strain to ducks and geese is harmless. In pigeons slight
pathological findings were observed in the respiratory tract, but no clinical
symptoms occurred.
Special precautions to be taken by the person administering the veterinary
medicinal product to animals:
ND-virus can induce conjunctivitis upon contact to eyes. Therefore during spraying
eye- and inhalation protection (face mask/visors) must be worn.
Upon contact of the veterinary medicinal product to eyes seek medical advice.
Wash and disinfect hands and equipment after application.
Special precautions for the protection of the environment:
Not applicable.

No information is available on the safety and efficacy of this vaccine when used with
any other veterinary medicinal product. A decision to use this vaccine before or after
any other veterinary medicinal product therefore needs to be made on a case by
case basis.

Store and transport refrigerated (2 C – 8 C).
Do not freeze.
Protect from light.

Zero days.

This information is sourced from the official Summary of Product Characteristics (SPC) published by the Veterinary Medicines Directorate (VMD). It is provided for informational purposes only and does not replace professional veterinary advice. Always consult your vet before administering any medication.