Apitraz 500 mg Bee-hive Strips for Honey Bees

All colonies in the same apiary should be treated simultaneously to avoid reinfestation
by robbery.
Do not re-use the strips.
It is recommended not to use the product before the end of the honey producing
season of the year. See also section 3.9 for Precautions of use and application
timetable and section 3.12.
Bee colonies should be monitored routinely for the level of varroa mite infestation
during treatment and also for a period thereafter.
The product should be used as part of an integrated varroa control program.
Inappropriate use of the product could result in an increased risk of resistance
development and could ultimately result in ineffective therapy.
Amitraz resistance has been reported in some populations of Varroa mites.
In countries with recognized amitraz resistance or in case of suspicion of amitraz
resistance, the use of the product should ideally be based on results of susceptibility
testing (e.g. Beltsville test). Please speak to your veterinarian or local bee inspector
for further information.
The safety and efficacy of the veterinary medicinal product has only been
investigated in hives with a single brood chamber (dose of 2 strips per hive/brood
chamber). No information is available on the safety and efficacy in hives with more
than one brood chamber.
In the presence of brood and depending upon the initial infestation level, an adequate
mite reduction above 95% is expected to occur at the end of the 10-weeks of
treatment.

Special precautions for safe use in the target species:
The safety profile for the product has not been established in weak colonies, i.e.
those colonies containing a number of bees that is lower than expected for the time
of year.
Do not exceed or reduce the recommended dose and recommended duration of use.
Remove the strips at the end of treatment.
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Special precautions to be taken by the person administering the veterinary medicinal
product to animals:
This veterinary medicinal product contains amitraz, which can lead to neurological
side-effects in humans.
Amitraz is a monoamine oxidase inhibitor (MAOI); therefore, people taking MAOI-
containing medication should take particular care.
Handle and open container with care to minimise the potential for inhalation.
This veterinary medicinal product may cause skin sensitisation, allergic reactions and
eye irritation.
Personal protective equipment consisting of impervious gloves and the usual
beekeeping protective clothing should be worn when handling the veterinary
medicinal product.
Avoid contact with skin. In case of contact, wash thoroughly with soap and water.
Avoid contact with eyes. In case of contact, rinse with plenty of water immediately.
If irritation occurs, seek immediate medical advice and show the package leaflet or
label to the physician.
Do not eat, drink or smoke during its use.
Wash your hands thoroughly after use.
In case of accidental ingestion or inhalation, seek medical advice immediately and
show the the package leaflet or label to the physician.
Special precautions for the protection of the environment:
Do not throw strips or empty sachets in ponds or streams, as the product could be
dangerous for fish and aquatic organisms.