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POM-V Prescription Required Companion Animal

Virbagen L

Active ingredients: Leptospira canicola, Leptospira icterohaemorrhagiae

Form

Injection

Species

Dogs

Manufacturer

Virbac

VMD MA No.

05653/4047

What it's used for

For active immunisation of dogs against: - L. interrogans serogroup Canicola serovar Canicola to reduce infection and urinary excretion - L. interrogans se...

Full indications, dosage and side effects ↓
View official SPC (PDF)

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  1. 1

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    They must provide one on request. Under the CMA Order the fee is capped at £21 from 2027.

  2. 2

    Fill it at a registered online retailer

    The CMA found online pharmacies 50–60% cheaper than practice dispensing on common medicines — typically £200–£300 a year.

Prescription required

Your vet must provide a written prescription on request. You can then purchase from any licensed online retailer.

Clinical information

Virbagen L — SPC Details

Source: VMD Summary of Product Characteristics (SPC). Last updated 27 Mar 2026.

For active immunisation of dogs against:
- L. interrogans serogroup Canicola serovar Canicola to reduce infection and urinary
excretion
- L. interrogans serogroup Icterohaemorrhagiae serovar Copenhageni to reduce
infection and urinary excretion
- L. interrogans

Amended pages: April 2024
AN: 03116/2022
- L. kirschneri serogroup Grippotyphosa serovar Bananal/Lianguang to reduce
infection and urinary excretion
Onset of immunity: 3 weeks.
Duration of immunity: 1 year.
None.
Dogs:
Very common
(>1 animal / 10 animals
treated):
Injection site swelling
,
Injection site nodule
,
Injection site pain
,
Elevated temperature
,
Decreased activity
,
Decreased appetite
.
Very rare
(<1 animal / 10,000 animals
treated, including isolated
reports):
Hypersensitivity reactions
,
Immune mediated haemolytic anaemia,
Immune mediated thrombocytopenia,
Immune mediated polyarthritis.
≤ 4 cm; subsides within 14 days.
Subsides within 14 days.
≤ 1 °C, up to 3 days.
In pups.

Amended pages: April 2024
AN: 03116/2022
Reactions are transient. This includes anaphylaxis (sometimes fatal). If such reaction
occurs, appropriate treatment should be administered without delay.
Reporting adverse events is important. It allows continuous safety monitoring of a
veterinary medicinal product. Reports should be sent, preferably via a veterinarian, to
either the marketing authorisation holder or the national competent authority via the
national reporting system. See also section 16 of the package leaflet for contact
details.
Vaccinate healthy animals only.

Special precautions for use in animals
Not applicable.
Special precautions to be taken by the person administering the veterinary medicinal
product to animals
Avoid accidental self-injection or contact with the eyes. In case of ocular irritation,
seek medical advice immediately and show the package leaflet or the label to the
physician.
Special precautions for the protection of the environment
Not applicable.
Other precautions
Not applicable.
Safety and efficacy data are available which demonstrate that this vaccine can be
mixed and administered with vaccines in the Canigen range containing canine
distemper virus, canine adenovirus type 2 , canine parvovirus (strain 154) and/or
canine parainfluenza virus components for subcutaneous administration. The product
information of the relevant Canigen vaccines should be consulted before
administration of the mixed product. When mixed with these Canigen vaccines, the
demonstrated safety and efficacy claims for Canigen Lepto 4 are no different from
those described for Canigen Lepto 4 alone. When mixed with Canigen vaccines
containing canine parainfluenza virus at annual revaccination, it has been
established that there is no interference with the anamnestic response induced by
the injectable canine parainfluenza virus component.
Safety and efficacy data are available which demonstrate that this vaccine can be
administered on the same day but not mixed with vaccines in the Canigen range
containing
intranasal administration.
Safety data are available which demonstrate that this vaccine can be administered at
the same time but not mixed with the inactivated vaccine in the Canigen range
against . When this vaccine is administered in association
with the inactivated vaccine in the Canigen range against Bordetella bronchiseptica
the demonstrated antibody response data and other immunity data of this vaccine
are the same as when this vaccine is administered alone.
No information is available on the safety and efficacy of this vaccine when used with
any other veterinary medicinal product except the products mentioned above. A
decision to use this vaccine before or after any other veterinary medicinal product
therefore needs to be made on a case by case basis.
Store in a refrigerator (2 C – 8 C).
Do not freeze.
Protect from light.
Not applicable
5.IMMUNOLOGICAL PROPERTIES
ATC Vet Code: QI07AB01
To stimulate active immunity against Leptospira canicola and Leptospira
ictero-haemorrhagiae.

This information is sourced from the official Summary of Product Characteristics (SPC) published by the Veterinary Medicines Directorate (VMD). It is provided for informational purposes only and does not replace professional veterinary advice. Always consult your vet before administering any medication.

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